Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              17    3301
XP_005269721                                                           17    3301
NP_003226                                                              17    4312
XP_005251100                                                           17    4312
XP_006716686                                                           17    4312
XP_005251099                                                           17    4312
XP_005251097                                                           17    4312
XP_005251095                                                           17    4312
XP_006716685                                                           17    4312
NP_001277155                                                           16    5631
NP_001277156                                                           16    5631
NP_055998                                                              16    5631
NP_001018065                                                           16    5631
NP_077308                                                              16    5631
NP_001229569                                                           16    5631
NP_001158136                                                           16    5631
XP_005274808                                                           16    5631
XP_005274807                                                           16    5631
XP_005274806                                                           16    5631
XP_006724909                                                           16    5631
XP_006714675                                                           16    5631
XP_006714673                                                           16    5631
XP_006714672                                                           16    5631
XP_006714670                                                           16    5631
XP_006714669                                                           16    5631
XP_006714668                                                           16    5631
XP_006714667                                                           16    5631
XP_006714666                                                           16    5631
XP_005248555                                                           16    5631
XP_006714665                                                           16    5631
NP_001098015                                                           16    7355
NP_060408                                                              16    7355
NP_001098014                                                           16    7355
NP_055690                                                              16    7355

>NP_036462
          Length = 2073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS SSQKSS
Sbjct: 503 QSPSSQKSS 511



>XP_005269721
          Length = 2073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS SSQKSS
Sbjct: 503 QSPSSQKSS 511



>NP_003226
          Length = 2768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>XP_005251100
          Length = 2103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>XP_006716686
          Length = 2111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>XP_005251099
          Length = 2121

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>XP_005251097
          Length = 2178

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>XP_005251095
          Length = 2704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1806 QSLSSQK 1812



>XP_006716685
          Length = 2747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    QSLSSQK 7
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876



>NP_001277155
          Length = 2417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2004 RSLSSQKPS 2012



>NP_001277156
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 1949 RSLSSQKPS 1957



>NP_055998
          Length = 2434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2021 RSLSSQKPS 2029



>NP_001018065
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 174 QSIQAQKSS 182



>NP_077308
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 174 QSIQAQKSS 182



>NP_001229569
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 175 QSIQAQKSS 183



>NP_001158136
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2210 RSLSSQKPS 2218



>XP_005274808
          Length = 317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 175 QSIQAQKSS 183



>XP_005274807
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QSLSSQKSS 9
          QS+ +QKSS
Sbjct: 60 QSIQAQKSS 68



>XP_005274806
          Length = 247

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 174 QSIQAQKSS 182



>XP_006724909
          Length = 248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           QS+ +QKSS
Sbjct: 175 QSIQAQKSS 183



>XP_006714675
          Length = 2275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 1862 RSLSSQKPS 1870



>XP_006714673
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 1949 RSLSSQKPS 1957



>XP_006714672
          Length = 2414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2001 RSLSSQKPS 2009



>XP_006714670
          Length = 2425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2012 RSLSSQKPS 2020



>XP_006714669
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2016 RSLSSQKPS 2024



>XP_006714668
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2016 RSLSSQKPS 2024



>XP_006714667
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2019 RSLSSQKPS 2027



>XP_006714666
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2019 RSLSSQKPS 2027



>XP_005248555
          Length = 2626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2213 RSLSSQKPS 2221



>XP_006714665
          Length = 2651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    QSLSSQKSS 9
            +SLSSQK S
Sbjct: 2238 RSLSSQKPS 2246



>NP_001098015
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QSLSSQKSS 9
          QSL+ Q+SS
Sbjct: 3  QSLTQQRSS 11



>NP_060408
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QSLSSQKSS 9
          QSL+ Q+SS
Sbjct: 3  QSLTQQRSS 11



>NP_001098014
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QSLSSQKSS 9
          QSL+ Q+SS
Sbjct: 3  QSLTQQRSS 11



>NP_055690
          Length = 1648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLSSQKSS 9
           Q LSSQK++
Sbjct: 967 QELSSQKAA 975



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.262   0.0786    0.149 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 255,636
Number of extensions: 289
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 19 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.2 bits)
S2: 28 (15.4 bits)