Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           19     665
NP_001020014                                                           19     665
NP_055903                                                              19     665
NP_001269407                                                           17    3301
NP_001269408                                                           17    3301
XP_006725124                                                           17    3301
XP_005272459                                                           17    3301
XP_005266104                                                           17    3301
NP_001123572                                                           17    4312
NP_001123571                                                           17    4312
NP_005541                                                              17    4312
XP_006721253                                                           17    4312
XP_005256003                                                           17    4312
XP_005256002                                                           17    4312
XP_005256001                                                           17    4312
XP_006721252                                                           17    4312
XP_005256000                                                           17    4312
XP_005255994                                                           17    4312
XP_006721251                                                           17    4312
NP_002145                                                              16    5631
NP_055811                                                              16    5631
NP_001116307                                                           16    5631
NP_078801                                                              16    5631
XP_005247296                                                           16    5631
XP_006713604                                                           16    5631
XP_005247295                                                           16    5631
XP_005273319                                                           16    5631
XP_005273318                                                           16    5631
XP_005273317                                                           16    5631
NP_001124432                                                           16    5631
NP_001124433                                                           16    5631
NP_054733                                                              16    7355
NP_065955                                                              16    7355
NP_001154826                                                           16    7355
NP_055426                                                              16    7355
NP_061927                                                              16    7355
XP_006723364                                                           16    7355
XP_005259166                                                           16    7355
XP_005259165                                                           16    7355
XP_005259164                                                           16    7355
XP_006717969                                                           16    7355
XP_005269977                                                           16    7355
XP_006717968                                                           16    7355
XP_006717967                                                           16    7355
XP_006717966                                                           16    7355
XP_006717965                                                           16    7355
XP_005248757                                                           16    7355
XP_006715468                                                           16    7355
XP_005248756                                                           16    7355
XP_006715467                                                           16    7355
NP_065805                                                              15    9605
NP_001273135                                                           15    9605
NP_055710                                                              15    9605
NP_775656                                                              15    9605
NP_002596                                                              15    9605
NP_001230066                                                           15    9605
NP_060907                                                              15    9605
NP_932095                                                              15    9605
XP_006724601                                                           15    9605
XP_006720630                                                           15    9605
XP_005254990                                                           15    9605
XP_005252145                                                           15    9605
XP_006717237                                                           15    9605
XP_005252143                                                           15    9605
XP_006715443                                                           15    9605
XP_005248732                                                           15    9605
XP_005248731                                                           15    9605
XP_005247728                                                           15    9605
XP_006713777                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            QSLET QNQ
Sbjct: 1747 QSLETGQNQ 1755
>NP_001020014
          Length = 1029

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLET QNQ
Sbjct: 943 QSLETGQNQ 951
>NP_055903
          Length = 1723

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            QSLET QNQ
Sbjct: 1637 QSLETGQNQ 1645
>NP_001269407
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QSLETDQNQ 9
          QSLE  QNQ
Sbjct: 63 QSLELPQNQ 71
>NP_001269408
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QSLETDQNQ 9
          QSLE  QNQ
Sbjct: 63 QSLELPQNQ 71
>XP_006725124
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QSLETDQNQ 9
          QSLE  QNQ
Sbjct: 63 QSLELPQNQ 71
>XP_005272459
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QSLETDQNQ 9
          QSLE  QNQ
Sbjct: 63 QSLELPQNQ 71
>XP_005266104
          Length = 279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QSLETDQNQ 9
          QSLE  QNQ
Sbjct: 63 QSLELPQNQ 71
>NP_001123572
          Length = 826

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 333 QSLEEDKNR 341
>NP_001123571
          Length = 687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 194 QSLEEDKNR 202
>NP_005541
          Length = 833

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 333 QSLEEDKNR 341
>XP_006721253
          Length = 828

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 328 QSLEEDKNR 336
>XP_005256003
          Length = 768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 275 QSLEEDKNR 283
>XP_005256002
          Length = 769

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 276 QSLEEDKNR 284
>XP_005256001
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 275 QSLEEDKNR 283
>XP_006721252
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 275 QSLEEDKNR 283
>XP_005256000
          Length = 776

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 276 QSLEEDKNR 284
>XP_005255994
          Length = 996

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 496 QSLEEDKNR 504
>XP_006721251
          Length = 1022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE D+N+
Sbjct: 522 QSLEEDKNR 530
>NP_002145
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSLETDQN 8
           + +ETDQN
Sbjct: 508 EPMETDQN 515
>NP_055811
          Length = 1655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 170 QEADTDENQ 178
>NP_001116307
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE ++NQ
Sbjct: 221 QSLELNKNQ 229
>NP_078801
          Length = 860

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE ++NQ
Sbjct: 274 QSLELNKNQ 282
>XP_005247296
          Length = 1673

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 188 QEADTDENQ 196
>XP_006713604
          Length = 1685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 200 QEADTDENQ 208
>XP_005247295
          Length = 1705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 200 QEADTDENQ 208
>XP_005273319
          Length = 807

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE ++NQ
Sbjct: 221 QSLELNKNQ 229
>XP_005273318
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE ++NQ
Sbjct: 243 QSLELNKNQ 251
>XP_005273317
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLETDQNQ 9
           QSLE ++NQ
Sbjct: 274 QSLELNKNQ 282
>NP_001124432
          Length = 1693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 188 QEADTDENQ 196
>NP_001124433
          Length = 1002

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSLETDQNQ 9
           Q  +TD+NQ
Sbjct: 188 QEADTDENQ 196
>NP_054733
          Length = 2136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SLETDQN 8
           +LETD+N
Sbjct: 492 ALETDEN 498
>NP_065955
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 360 QSLETD 365
>NP_001154826
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 335 QSLETD 340
>NP_055426
          Length = 5596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ETDQNQ 9
            ETDQN+
Sbjct: 4929 ETDQNE 4934
>NP_061927
          Length = 835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 706 LETDENR 712
>XP_006723364
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 335 QSLETD 340
>XP_005259166
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 360 QSLETD 365
>XP_005259165
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 360 QSLETD 365
>XP_005259164
          Length = 754

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSLETD 6
           QSLETD
Sbjct: 335 QSLETD 340
>XP_006717969
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 310 LETDENR 316
>XP_005269977
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 426 LETDENR 432
>XP_006717968
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 823 LETDENR 829
>XP_006717967
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 823 LETDENR 829
>XP_006717966
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 823 LETDENR 829
>XP_006717965
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETDQNQ 9
           LETD+N+
Sbjct: 829 LETDENR 835
>XP_005248757
          Length = 3591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ETDQNQ 9
            ETDQN+
Sbjct: 2924 ETDQNE 2929
>XP_006715468
          Length = 3744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ETDQNQ 9
            ETDQN+
Sbjct: 3077 ETDQNE 3082
>XP_005248756
          Length = 3905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ETDQNQ 9
            ETDQN+
Sbjct: 3238 ETDQNE 3243
>XP_006715467
          Length = 5550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ETDQNQ 9
            ETDQN+
Sbjct: 4929 ETDQNE 4934
>NP_065805
          Length = 1444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETDQNQ 9
           SLE D+N+
Sbjct: 223 SLENDENR 230
>NP_001273135
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            Q +ET+QN+
Sbjct: 1266 QVVETEQNK 1274
>NP_055710
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            Q +ET+QN+
Sbjct: 1342 QVVETEQNK 1350
>NP_775656
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETDQNQ 9
           ETD+NQ
Sbjct: 650 ETDKNQ 655
>NP_002596
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETDQNQ 9
           ETD+NQ
Sbjct: 696 ETDKNQ 701
>NP_001230066
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETDQNQ 9
           ETD+NQ
Sbjct: 624 ETDKNQ 629
>NP_060907
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           L+TDQN
Sbjct: 272 LDTDQN 277
>NP_932095
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           L+TDQN
Sbjct: 272 LDTDQN 277
>XP_006724601
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           +ETDQN
Sbjct: 749 VETDQN 754
>XP_006720630
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETDQNQ 9
           ETD+NQ
Sbjct: 449 ETDKNQ 454
>XP_005254990
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETDQNQ 9
           ETD+NQ
Sbjct: 506 ETDKNQ 511
>XP_005252145
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           L+TDQN
Sbjct: 97  LDTDQN 102
>XP_006717237
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           L+TDQN
Sbjct: 272 LDTDQN 277
>XP_005252143
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LETDQN 8
           L+TDQN
Sbjct: 272 LDTDQN 277
>XP_006715443
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            Q +ET+QN+
Sbjct: 1266 QVVETEQNK 1274
>XP_005248732
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            Q +ET+QN+
Sbjct: 1269 QVVETEQNK 1277
>XP_005248731
          Length = 1365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QSLETDQNQ 9
            Q +ET+QN+
Sbjct: 1304 QVVETEQNK 1312
>XP_005247728
          Length = 1413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETDQNQ 9
           SLE D+N+
Sbjct: 192 SLENDENR 199
>XP_006713777
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETDQNQ 9
           SLE D+N+
Sbjct: 223 SLENDENR 230
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285    0.104    0.242 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 518,174
Number of extensions: 932
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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