Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185763                                                           21     229
NP_055459                                                              21     229
XP_006711718                                                           21     229
XP_006711716                                                           21     229
XP_006711715                                                           21     229
XP_006711714                                                           21     229
XP_006711713                                                           21     229
XP_006711712                                                           21     229
XP_006711710                                                           21     229
XP_006711709                                                           21     229
XP_005277503                                                           21     229
XP_005273038                                                           21     229
XP_006711708                                                           21     229
XP_005277500                                                           21     229
XP_006711707                                                           21     229
XP_005277499                                                           21     229
XP_006711706                                                           21     229
XP_006711705                                                           21     229
XP_006710142                                                           21     229
XP_006710141                                                           21     229
NP_853654                                                              17    3301
NP_004100                                                              16    5631
NP_005036                                                              16    7355
NP_774959                                                              16    7355
NP_003493                                                              16    7355
NP_851393                                                              16    7355
NP_005016                                                              16    7355
NP_001116224                                                           16    7355
XP_005255667                                                           16    7355
XP_005255666                                                           16    7355
XP_005255665                                                           16    7355
XP_005255664                                                           16    7355
XP_006713720                                                           16    7355
NP_000525                                                              15    9605
NP_001121615                                                           15    9605
NP_001121616                                                           15    9605
NP_000526                                                              15    9605
NP_057533                                                              15    9605
NP_001180360                                                           15    9605
NP_001554                                                              15    9605
NP_057051                                                              15    9605
NP_036543                                                              15    9605
NP_001269297                                                           15    9605
NP_000048                                                              15    9605
NP_001274177                                                           15    9605
NP_001274176                                                           15    9605
NP_001274175                                                           15    9605
NP_056075                                                              15    9605
NP_071937                                                              15    9605
XP_006726899                                                           15    9605
XP_006724472                                                           15    9605
XP_005261681                                                           15    9605
XP_006724322                                                           15    9605
XP_006722767                                                           15    9605
XP_005259889                                                           15    9605
XP_006720695                                                           15    9605
XP_005250670                                                           15    9605
XP_006716205                                                           15    9605
XP_006715806                                                           15    9605
XP_006715805                                                           15    9605
XP_005246706                                                           15    9605
XP_005246704                                                           15    9605
XP_006712140                                                           15    9605
XP_005264554                                                           15    9605
XP_005264553                                                           15    9605
XP_005264550                                                           15    9605
XP_005264549                                                           15    9605
XP_005264548                                                           15    9605
XP_005270795                                                           15    9605
XP_006710183                                                           15    9605
>NP_001185763
          Length = 2362

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1177 QSLDLGATF 1185
>NP_055459
          Length = 2346

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1177 QSLDLGATF 1185
>XP_006711718
          Length = 1436

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QSLDIGATF 9
           QSLD+GATF
Sbjct: 184 QSLDLGATF 192
>XP_006711716
          Length = 2411

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1243 QSLDLGATF 1251
>XP_006711715
          Length = 2428

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1177 QSLDLGATF 1185
>XP_006711714
          Length = 2429

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1177 QSLDLGATF 1185
>XP_006711713
          Length = 2432

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1180 QSLDLGATF 1188
>XP_006711712
          Length = 2473

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006711710
          Length = 2494

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1243 QSLDLGATF 1251
>XP_006711709
          Length = 2495

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1243 QSLDLGATF 1251
>XP_005277503
          Length = 2498

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_005273038
          Length = 2509

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006711708
          Length = 2512

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_005277500
          Length = 2525

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006711707
          Length = 2553

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_005277499
          Length = 2561

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006711706
          Length = 2591

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006711705
          Length = 2592

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSLDIGATF 9
            QSLD+GATF
Sbjct: 1340 QSLDLGATF 1348
>XP_006710142
          Length = 671

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QSLDIGATF 9
           QSLD+GATF
Sbjct: 129 QSLDLGATF 137
>XP_006710141
          Length = 672

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QSLDIGATF 9
           QSLD+GATF
Sbjct: 129 QSLDLGATF 137
>NP_853654
          Length = 137

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSLDIGATF 9
           QSLD G++F
Sbjct: 113 QSLDCGSSF 121
>NP_004100
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSLDIGAT 8
           QS+D+G T
Sbjct: 176 QSIDVGKT 183
>NP_005036
          Length = 3460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSLDIGATF 9
           QS+ IGA++
Sbjct: 918 QSMQIGASY 926
>NP_774959
          Length = 3458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSLDIGATF 9
           QS+ IGA++
Sbjct: 918 QSMQIGASY 926
>NP_003493
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 10 LDLGASF 16
>NP_851393
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 10 LDLGASF 16
>NP_005016
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QSLDIGATF 9
          QS+  GATF
Sbjct: 13 QSMATGATF 21
>NP_001116224
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QSLDIGATF 9
          QS+  GATF
Sbjct: 13 QSMATGATF 21
>XP_005255667
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 59 LDLGASF 65
>XP_005255666
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 10 LDLGASF 16
>XP_005255665
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 59 LDLGASF 65
>XP_005255664
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LDIGATF 9
          LD+GA+F
Sbjct: 59 LDLGASF 65
>XP_006713720
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QSLDIGATF 9
          QS+  GATF
Sbjct: 13 QSMATGATF 21
>NP_000525
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 32 SLDAGAT 38
>NP_001121615
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 32 SLDAGAT 38
>NP_001121616
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 32 SLDAGAT 38
>NP_000526
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 46 SLDAGAT 52
>NP_057533
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LDIGAT 8
          LD+GAT
Sbjct: 49 LDVGAT 54
>NP_001180360
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QSLDIGA 7
           QSLD+G+
Sbjct: 413 QSLDLGS 419
>NP_001554
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QSLDIG 6
           QSLD+G
Sbjct: 367 QSLDVG 372
>NP_057051
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QSLDIGA 7
           QSLD+G+
Sbjct: 413 QSLDLGS 419
>NP_036543
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QSLDIGA 7
           QSLD+G+
Sbjct: 358 QSLDLGS 364
>NP_001269297
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QSLDIG 6
           QSLD+G
Sbjct: 289 QSLDVG 294
>NP_000048
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLDI AT+
Sbjct: 729 SLDIPATY 736
>NP_001274177
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLDI AT+
Sbjct: 354 SLDIPATY 361
>NP_001274176
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLDI AT+
Sbjct: 729 SLDIPATY 736
>NP_001274175
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLDI AT+
Sbjct: 729 SLDIPATY 736
>NP_056075
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSLDIGAT 8
           Q LD+GA+
Sbjct: 702 QQLDLGAS 709
>NP_071937
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_006726899
          Length = 197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDIGAT 8
           LD+GAT
Sbjct: 95  LDVGAT 100
>XP_006724472
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDIGAT 8
           LD+GAT
Sbjct: 98  LDVGAT 103
>XP_005261681
          Length = 145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LDIGAT 8
          LD+GAT
Sbjct: 49 LDVGAT 54
>XP_006724322
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LDIGAT 8
          LD+GAT
Sbjct: 49 LDVGAT 54
>XP_006722767
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSLDIGAT 8
           Q LD+GA+
Sbjct: 185 QQLDLGAS 192
>XP_005259889
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSLDIGAT 8
           Q LD+GA+
Sbjct: 670 QQLDLGAS 677
>XP_006720695
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLDIGATF 9
          SLDI AT+
Sbjct: 75 SLDIPATY 82
>XP_005250670
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLDIGAT 8
           SLD GAT
Sbjct: 192 SLDAGAT 198
>XP_006716205
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLDIGAT 8
           SLD GAT
Sbjct: 192 SLDAGAT 198
>XP_006715806
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 46 SLDAGAT 52
>XP_006715805
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 44 SLDAGAT 50
>XP_005246706
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 32 SLDAGAT 38
>XP_005246704
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SLDIGAT 8
          SLD GAT
Sbjct: 32 SLDAGAT 38
>XP_006712140
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SLDIGATF 9
          SLD+ +TF
Sbjct: 86 SLDLSSTF 93
>XP_005264554
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_005264553
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_005264550
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_005264549
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_005264548
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLDIGATF 9
           SLD+ +TF
Sbjct: 230 SLDLSSTF 237
>XP_005270795
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QSLDIGA 7
           QSLD+G+
Sbjct: 389 QSLDLGS 395
>XP_006710183
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDIGAT 8
           LD+GAT
Sbjct: 98  LDVGAT 103
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.137    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 423,451
Number of extensions: 469
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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