Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     299
NP_001120965                                                           16    5631
NP_066187                                                              16    5631
NP_001139                                                              16    5631
XP_006714256                                                           16    5631
XP_006714255                                                           16    5631
XP_005263005                                                           16    5631
XP_006714254                                                           16    5631
XP_006714253                                                           16    5631
XP_005263002                                                           16    5631
XP_005262999                                                           16    5631
XP_006714252                                                           16    5631
XP_006714251                                                           16    5631
NP_006083                                                              16    7355
XP_006715700                                                           16    7355
XP_006715699                                                           16    7355
XP_005249632                                                           16    7355
XP_005249631                                                           16    7355
XP_005249630                                                           16    7355
XP_006715698                                                           16    7355
XP_006715697                                                           16    7355
XP_005249629                                                           16    7355
XP_006715696                                                           16    7355
XP_005249625                                                           16    7355
NP_001273886                                                           15    9605
NP_149115                                                              15    9605
NP_001207423                                                           15    9605
NP_001207425                                                           15    9605
NP_542392                                                              15    9605
XP_006719734                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSKVMVNYM 9
           QSKVM NYM
Sbjct: 506 QSKVMANYM 514
>NP_001120965
          Length = 1863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 200 QSKMMVN 206
>NP_066187
          Length = 1872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>NP_001139
          Length = 3957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>XP_006714256
          Length = 1901

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714255
          Length = 1970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_005263005
          Length = 2019

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714254
          Length = 2049

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714253
          Length = 2069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_005263002
          Length = 4072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>XP_005262999
          Length = 4147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714252
          Length = 4153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714251
          Length = 4165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>NP_006083
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715700
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715699
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249632
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249631
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249630
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715698
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715697
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249629
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715696
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249625
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QSKVMVN 7
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>NP_001273886
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKVMVNYM 9
           +KVMV+Y+
Sbjct: 249 TKVMVDYI 256
>NP_149115
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKVMVNYM 9
           +KVMV+Y+
Sbjct: 392 TKVMVDYI 399
>NP_001207423
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SKVMVNYM 9
           ++VMV YM
Sbjct: 245 ARVMVRYM 252
>NP_001207425
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SKVMVNYM 9
           ++VMV YM
Sbjct: 245 ARVMVRYM 252
>NP_542392
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SKVMVNYM 9
           ++VMV YM
Sbjct: 276 ARVMVRYM 283
>XP_006719734
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKVMVNYM 9
           +KVMV+Y+
Sbjct: 319 TKVMVDYI 326
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.121    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 307,144
Number of extensions: 297
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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