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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           20     509
NP_000170                                                              20     509
NP_001268422                                                           20     509
NP_001268423                                                           20     509
XP_005264328                                                           20     509
NP_001177738                                                           17    2528
NP_068750                                                              17    2528
NP_001360                                                              16    7355
NP_001258875                                                           16    7355
NP_003053                                                              16    7355
NP_067019                                                              16    7355
NP_077006                                                              16    7355
NP_055299                                                              16    7355
XP_005248319                                                           16    7355
XP_006712802                                                           16    7355
XP_006712801                                                           16    7355
XP_006712800                                                           16    7355
NP_597812                                                              16    7355
NP_001177766                                                           15    9605
NP_001128512                                                           15    9605
NP_004073                                                              15    9605
NP_075408                                                              15    9605
NP_001128513                                                           15    9605
NP_001177765                                                           15    9605
NP_065970                                                              15    9605
NP_061485                                                              15    9605
NP_008839                                                              15    9605
NP_000035                                                              15    9605
NP_002863                                                              15    9605
NP_775924                                                              15    9605
XP_006724349                                                           15    9605
XP_005256447                                                           15    9605
XP_006712718                                                           15    9605
XP_005246766                                                           15    9605
XP_006712717                                                           15    9605
NP_005043                                                              15    9605

>NP_001268421
          Length = 1230

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSAVECI V
Sbjct: 918 QSAVECIAV 926



>NP_000170
          Length = 1360

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSAVECIVV 9
            QSAVECI V
Sbjct: 1048 QSAVECIAV 1056



>NP_001268422
          Length = 1058

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSAVECI V
Sbjct: 746 QSAVECIAV 754



>NP_001268423
          Length = 1058

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSAVECI V
Sbjct: 746 QSAVECIAV 754



>XP_005264328
          Length = 1261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSAVECI V
Sbjct: 949 QSAVECIAV 957



>NP_001177738
          Length = 672

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSAVECIVV 9
           ++A+EC+VV
Sbjct: 340 RTAIECLVV 348



>NP_068750
          Length = 703

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSAVECIVV 9
           ++A+EC+VV
Sbjct: 371 RTAIECLVV 379



>NP_001360
          Length = 4624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AVECIV 8
            AVECI+
Sbjct: 1037 AVECII 1042



>NP_001258875
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QSAVECIVV 9
            Q+  +CIVV
Sbjct: 1136 QNGAQCIVV 1144



>NP_003053
          Length = 1523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QSAVECIVV 9
            Q+  +CIVV
Sbjct: 1129 QNGAQCIVV 1137



>NP_067019
          Length = 1137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SAVECIVV 9
           SAV+C+++
Sbjct: 613 SAVQCLIL 620



>NP_077006
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SAVECIV 8
           SAVEC++
Sbjct: 349 SAVECLL 355



>NP_055299
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAVECI 7
           SAVEC+
Sbjct: 150 SAVECV 155



>XP_005248319
          Length = 4609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    AVECIV 8
            AVECI+
Sbjct: 1022 AVECII 1027



>XP_006712802
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SAVECIV 8
           SAVEC++
Sbjct: 349 SAVECLL 355



>XP_006712801
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SAVECIV 8
           SAVEC++
Sbjct: 349 SAVECLL 355



>XP_006712800
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SAVECIV 8
           SAVEC++
Sbjct: 309 SAVECLL 315



>NP_597812
          Length = 1121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   SAVECIVV 9
           SAV+C+++
Sbjct: 613 SAVQCLIL 620



>NP_001177766
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 747 QSALDCMSV 755



>NP_001128512
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 734 QSALDCMSV 742



>NP_004073
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 754 QSALDCMSV 762



>NP_075408
          Length = 1144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 620 QSALDCMSV 628



>NP_001128513
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 620 QSALDCMSV 628



>NP_001177765
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSAVECIVV 9
           QSA++C+ V
Sbjct: 717 QSALDCMSV 725



>NP_065970
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    SAVECI 7
            SAVEC+
Sbjct: 1554 SAVECL 1559



>NP_061485
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



>NP_008839
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



>NP_000035
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QSAVEC 6
           QSA+EC
Sbjct: 120 QSALEC 125



>NP_002863
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



>NP_775924
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SAVECIVV 9
           +A+ CIV+
Sbjct: 170 TAISCIVI 177



>XP_006724349
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



>XP_005256447
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



>XP_006712718
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAVECI 7
           SAVEC+
Sbjct: 866 SAVECL 871



>XP_005246766
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    SAVECI 7
            SAVEC+
Sbjct: 1553 SAVECL 1558



>XP_006712717
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    SAVECI 7
            SAVEC+
Sbjct: 1554 SAVECL 1559



>NP_005043
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3 AVECIVV 9
         A++C+VV
Sbjct: 3 AIKCVVV 9



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.129    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,189
Number of extensions: 422
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)