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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              20     299
NP_003794                                                              18    1135
NP_062830                                                              18    1135
NP_001167535                                                           16    7355
NP_001167534                                                           16    7355
NP_001167536                                                           16    7355
NP_056934                                                              16    7355
NP_075598                                                              16    7355
NP_001167538                                                           16    7355
NP_001035915                                                           16    7355
NP_689564                                                              16    7355
NP_001257578                                                           16    7355
NP_001257577                                                           16    7355
NP_066568                                                              16    7355
NP_001139470                                                           16    7355
NP_006819                                                              16    7355
XP_006721514                                                           16    7355
XP_006721513                                                           16    7355
XP_005256514                                                           16    7355
XP_006716372                                                           16    7355
XP_006716371                                                           16    7355
XP_006716370                                                           16    7355
XP_006716369                                                           16    7355
XP_006716368                                                           16    7355
XP_006716367                                                           16    7355
XP_006716366                                                           16    7355
XP_006715385                                                           16    7355
XP_006713799                                                           16    7355
XP_005247779                                                           16    7355
NP_078858                                                              15    9605
NP_001278232                                                           15    9605
NP_001278214                                                           15    9605
NP_001271169                                                           15    9605
NP_001271170                                                           15    9605
NP_061872                                                              15    9605
XP_005269963                                                           15    9605
XP_005269962                                                           15    9605

>NP_004351
          Length = 882

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QRTAYFSLN 9
          QRTAYFSL+
Sbjct: 64 QRTAYFSLD 72



>NP_003794
          Length = 1685

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RTAYFSLN 9
            RTAYF++N
Sbjct: 1627 RTAYFTIN 1634



>NP_062830
          Length = 1589

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RTAYFSLN 9
            RTAYF++N
Sbjct: 1531 RTAYFTIN 1538



>NP_001167535
          Length = 812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 103 TTYFSVN 109



>NP_001167534
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>NP_001167536
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>NP_056934
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>NP_075598
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>NP_001167538
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 144 TTYFSVN 150



>NP_001035915
          Length = 596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>NP_689564
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>NP_001257578
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>NP_001257577
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>NP_066568
          Length = 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRTAYFSL 8
           +RT YFS+
Sbjct: 179 ERTRYFSV 186



>NP_001139470
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRTAYFSL 8
           +RT YFS+
Sbjct: 148 ERTRYFSV 155



>NP_006819
          Length = 2202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QRTAYFS 7
           +RT YFS
Sbjct: 971 ERTGYFS 977



>XP_006721514
          Length = 596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>XP_006721513
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>XP_005256514
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TAYFSLN 9
          T YF+LN
Sbjct: 25 TVYFALN 31



>XP_006716372
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 103 TTYFSVN 109



>XP_006716371
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006716370
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006716369
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006716368
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006716367
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006716366
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TAYFSLN 9
           T YFS+N
Sbjct: 111 TTYFSVN 117



>XP_006715385
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QRTAYFS 7
           +RT YFS
Sbjct: 635 ERTGYFS 641



>XP_006713799
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRTAYFSL 8
           +RT YFS+
Sbjct: 179 ERTRYFSV 186



>XP_005247779
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRTAYFSL 8
           +RT YFS+
Sbjct: 179 ERTRYFSV 186



>NP_078858
          Length = 4981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TAYFSLN 9
            T+YFSL+
Sbjct: 3555 TSYFSLS 3561



>NP_001278232
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TAYFSLN 9
            T+YFSL+
Sbjct: 3557 TSYFSLS 3563



>NP_001278214
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TAYFSLN 9
            T+YFSL+
Sbjct: 3557 TSYFSLS 3563



>NP_001271169
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTAYFSLN 9
           RT+Y S+N
Sbjct: 160 RTSYSSIN 167



>NP_001271170
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTAYFSLN 9
           RT+Y S+N
Sbjct: 160 RTSYSSIN 167



>NP_061872
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTAYFSLN 9
           RT+Y S+N
Sbjct: 160 RTSYSSIN 167



>XP_005269963
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTAYFSLN 9
           RT+Y S+N
Sbjct: 160 RTSYSSIN 167



>XP_005269962
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTAYFSLN 9
           RT+Y S+N
Sbjct: 160 RTSYSSIN 167



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.128    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 438,533
Number of extensions: 544
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)