Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     509
NP_001263689                                                           20     509
NP_001119584                                                           20     509
NP_001119586                                                           20     509
NP_001263625                                                           20     509
NP_001119590                                                           20     509
NP_001263690                                                           20     509
NP_001119585                                                           20     509
NP_001263624                                                           20     509
NP_001119588                                                           20     509
NP_001119587                                                           20     509
NP_001119589                                                           20     509
NP_001263627                                                           20     509
NP_001263628                                                           20     509
NP_001263626                                                           20     509
NP_001191121                                                           17    2528
NP_001119713                                                           17    2528
NP_001191117                                                           17    2528
NP_001119712                                                           17    2528
NP_001119714                                                           17    2528
NP_005418                                                              17    2528
NP_001191116                                                           17    2528
NP_001191115                                                           17    2528
NP_001191119                                                           17    2528
NP_001191113                                                           17    2528
NP_001191118                                                           17    2528
NP_001191120                                                           17    2528
NP_001191114                                                           17    2528
NP_001108451                                                           17    3301
NP_001108454                                                           17    3301
NP_003713                                                              17    3301
NP_001108450                                                           17    3301
NP_001108452                                                           17    3301
NP_001108453                                                           17    3301
XP_005247903                                                           17    3301
XP_005247901                                                           17    3301
XP_005247900                                                           17    3301
NP_038475                                                              17    4312
NP_001258949                                                           17    4312
NP_115960                                                              17    4312
NP_001257981                                                           17    4312
NP_001276087                                                           17    4312
XP_005259943                                                           17    4312
XP_005259942                                                           17    4312
XP_005259941                                                           17    4312
XP_006720385                                                           17    4312
XP_005268275                                                           17    4312
NP_001276088                                                           17    4312
NP_999875                                                              16    5631
NP_060050                                                              16    7355
XP_005269983                                                           16    7355
XP_005269982                                                           16    7355
XP_006717970                                                           16    7355
XP_006711598                                                           16    7355
XP_006711597                                                           16    7355
XP_006711595                                                           16    7355
XP_006711594                                                           16    7355
NP_110391                                                              16    7355
NP_001013597                                                           15    9605
NP_055463                                                              15    9605
NP_115677                                                              15    9605
XP_005260153                                                           15    9605
XP_005247976                                                           15    9605
XP_005247975                                                           15    9605
XP_005247974                                                           15    9605
XP_005247973                                                           15    9605
XP_005247972                                                           15    9605
XP_005247971                                                           15    9605
>NP_000537
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 248 RRPILTIIT 256
>NP_001263689
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 209 RRPILTIIT 217
>NP_001119584
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 248 RRPILTIIT 256
>NP_001119586
          Length = 341

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 248 RRPILTIIT 256
>NP_001263625
          Length = 302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 209 RRPILTIIT 217
>NP_001119590
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 209 RRPILTIIT 217
>NP_001263690
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 209 RRPILTIIT 217
>NP_001119585
          Length = 346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 248 RRPILTIIT 256
>NP_001263624
          Length = 307

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 209 RRPILTIIT 217
>NP_001119588
          Length = 209

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 116 RRPILTIIT 124
>NP_001119587
          Length = 261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 116 RRPILTIIT 124
>NP_001119589
          Length = 214

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QRPILTIIT 9
           +RPILTIIT
Sbjct: 116 RRPILTIIT 124
>NP_001263627
          Length = 182

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QRPILTIIT 9
          +RPILTIIT
Sbjct: 89 RRPILTIIT 97
>NP_001263628
          Length = 187

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QRPILTIIT 9
          +RPILTIIT
Sbjct: 89 RRPILTIIT 97
>NP_001263626
          Length = 234

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QRPILTIIT 9
          +RPILTIIT
Sbjct: 89 RRPILTIIT 97
>NP_001191121
          Length = 565

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 197 RRPILIIIT 205
>NP_001119713
          Length = 450

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_001191117
          Length = 540

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001119712
          Length = 587

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_001119714
          Length = 426

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_005418
          Length = 636

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001191116
          Length = 555

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001191115
          Length = 403

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001191119
          Length = 506

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_001191113
          Length = 499

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001191118
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_001191120
          Length = 491

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 219 RRPILIIIT 227
>NP_001191114
          Length = 475

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL IIT
Sbjct: 268 RRPILIIIT 276
>NP_001108451
          Length = 487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 318 RRPILIIVT 326
>NP_001108454
          Length = 393

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 224 RRPILIIVT 232
>NP_003713
          Length = 680

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 318 RRPILIIVT 326
>NP_001108450
          Length = 555

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 318 RRPILIIVT 326
>NP_001108452
          Length = 586

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 224 RRPILIIVT 232
>NP_001108453
          Length = 461

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 224 RRPILIIVT 232
>XP_005247903
          Length = 483

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 318 RRPILIIVT 326
>XP_005247901
          Length = 663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 301 RRPILIIVT 309
>XP_005247900
          Length = 676

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRPILTIIT 9
           +RPIL I+T
Sbjct: 318 RRPILIIVT 326
>NP_038475
          Length = 823

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 534 PVLTVIT 540
>NP_001258949
          Length = 637

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RPILTII 8
           RP+LTII
Sbjct: 362 RPLLTII 368
>NP_115960
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 354 PVLTVIT 360
>NP_001257981
          Length = 765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 476 PVLTVIT 482
>NP_001276087
          Length = 600

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 302 PVLTVIT 308
>XP_005259943
          Length = 551

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 262 PVLTVIT 268
>XP_005259942
          Length = 834

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 545 PVLTVIT 551
>XP_005259941
          Length = 892

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 603 PVLTVIT 609
>XP_006720385
          Length = 1683

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RPILTII 8
            RP+LTII
Sbjct: 1408 RPLLTII 1414
>XP_005268275
          Length = 1684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RPILTII 8
            RP+LTII
Sbjct: 1409 RPLLTII 1415
>NP_001276088
          Length = 526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PILTIIT 9
           P+LT+IT
Sbjct: 228 PVLTVIT 234
>NP_999875
          Length = 283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RPILTIIT 9
          RP+LT+ T
Sbjct: 10 RPLLTVAT 17
>NP_060050
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QRPILTIIT 9
          QRP  TIIT
Sbjct: 30 QRPSGTIIT 38
>XP_005269983
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QRPILTIIT 9
          QRP  TIIT
Sbjct: 30 QRPSGTIIT 38
>XP_005269982
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QRPILTIIT 9
          QRP  TIIT
Sbjct: 56 QRPSGTIIT 64
>XP_006717970
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QRPILTIIT 9
          QRP  TIIT
Sbjct: 56 QRPSGTIIT 64
>XP_006711598
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QRPILT 6
           QRP+LT
Sbjct: 107 QRPVLT 112
>XP_006711597
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QRPILT 6
           QRP+LT
Sbjct: 107 QRPVLT 112
>XP_006711595
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QRPILT 6
           QRP+LT
Sbjct: 107 QRPVLT 112
>XP_006711594
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QRPILT 6
           QRP+LT
Sbjct: 107 QRPVLT 112
>NP_110391
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QRPILT 6
           QRP+LT
Sbjct: 107 QRPVLT 112
>NP_001013597
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   RPILTII 8
           RPI+T++
Sbjct: 272 RPIVTVV 278
>NP_055463
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>NP_115677
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   RPILTII 8
           RP+LT++
Sbjct: 308 RPVLTLL 314
>XP_005260153
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   RPILTII 8
           RP+LT++
Sbjct: 145 RPVLTLL 151
>XP_005247976
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 771 RPILTV 776
>XP_005247975
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247974
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247973
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247972
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247971
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.148    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 631,308
Number of extensions: 1117
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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