Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_036367                                                              16    7355
XP_005265029                                                           16    7355
XP_005265028                                                           16    7355
XP_005265027                                                           16    7355
XP_005265026                                                           16    7355
XP_005265025                                                           16    7355
XP_005265024                                                           16    7355
XP_006713097                                                           16    7355
NP_054760                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLVMSGFA 9
            QRLV SGFA
Sbjct: 1823 QRLVRSGFA 1831
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLVMSGFA 9
            QRLV SGFA
Sbjct: 1823 QRLVRSGFA 1831
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLVMSGFA 9
            QRLV SGFA
Sbjct: 1776 QRLVRSGFA 1784
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLVMSGFA 9
            QRLV SGFA
Sbjct: 1855 QRLVRSGFA 1863
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLVMSGFA 9
            QRLV SGFA
Sbjct: 1855 QRLVRSGFA 1863
>NP_036367
          Length = 1279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 517 QRLIMAG 523
>XP_005265029
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 125 QRLIMAG 131
>XP_005265028
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 125 QRLIMAG 131
>XP_005265027
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 125 QRLIMAG 131
>XP_005265026
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 262 QRLIMAG 268
>XP_005265025
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 262 QRLIMAG 268
>XP_005265024
          Length = 1278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 517 QRLIMAG 523
>XP_006713097
          Length = 1279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QRLVMSG 7
           QRL+M+G
Sbjct: 517 QRLIMAG 523
>NP_054760
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVMSGFA 9
           +VM+GFA
Sbjct: 118 IVMAGFA 124
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.140    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 381,022
Number of extensions: 561
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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