Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     665
NP_036462                                                              19     665
NP_001243397                                                           19     665
XP_005269721                                                           19     665
NP_997205                                                              18    1482
NP_056045                                                              17    2528
NP_001036040                                                           17    2528
NP_006050                                                              17    2528
XP_005259266                                                           17    2528
XP_005259265                                                           17    2528
XP_006716984                                                           17    2528
XP_005262700                                                           17    2528
XP_005262697                                                           17    2528
XP_006714054                                                           17    2528
XP_005262695                                                           17    2528
XP_006713677                                                           17    2528
NP_001123468                                                           17    2528
NP_037492                                                              17    2528
NP_001138296                                                           17    3301
NP_037530                                                              17    3301
NP_006621                                                              17    3301
NP_037491                                                              17    3301
XP_005259278                                                           17    3301
XP_005259263                                                           17    3301
XP_006723038                                                           17    3301
XP_006723037                                                           17    3301
XP_006723036                                                           17    3301
NP_940927                                                              17    4312
NP_002861                                                              17    4312
NP_001258967                                                           17    4312
NP_002966                                                              17    4312
XP_006720560                                                           17    4312
XP_005254961                                                           17    4312
XP_005254960                                                           17    4312
XP_005254959                                                           17    4312
NP_543139                                                              17    4312
NP_945339                                                              16    5631
NP_005262                                                              16    7355
NP_110394                                                              16    7355
NP_056997                                                              16    7355
NP_055713                                                              16    7355
NP_065704                                                              16    7355
NP_036216                                                              16    7355
XP_005258722                                                           16    7355
XP_006723152                                                           16    7355
XP_006723151                                                           16    7355
XP_006723150                                                           16    7355
XP_005256800                                                           16    7355
XP_006721624                                                           16    7355
XP_006717358                                                           16    7355
XP_005252305                                                           16    7355
XP_005252303                                                           16    7355
XP_006717357                                                           16    7355
XP_005252304                                                           16    7355
XP_005252302                                                           16    7355
XP_005252301                                                           16    7355
XP_005252300                                                           16    7355
NP_072088                                                              16    7355
NP_004360                                                              15    9605
NP_877963                                                              15    9605
NP_476508                                                              15    9605
NP_002651                                                              15    9605
NP_476507                                                              15    9605
NP_002652                                                              15    9605
NP_997320                                                              15    9605
NP_612490                                                              15    9605
XP_005261428                                                           15    9605
XP_005261427                                                           15    9605
XP_005260495                                                           15    9605
XP_005253612                                                           15    9605
XP_005246123                                                           15    9605
XP_005246122                                                           15    9605
XP_006712316                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QRLRLGAK 8
           QRLRLGAK
Sbjct: 150 QRLRLGAK 157
>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QRLRLGAK 8
           QRLRLGAK
Sbjct: 150 QRLRLGAK 157
>NP_001243397
          Length = 1890

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QRLRLGAK 8
           QRLRLGAK
Sbjct: 150 QRLRLGAK 157
>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QRLRLGAK 8
           QRLRLGAK
Sbjct: 150 QRLRLGAK 157
>NP_997205
          Length = 369

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QRLRLGAKC 9
          +RLRLG +C
Sbjct: 5  ERLRLGPEC 13
>NP_056045
          Length = 1704

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +RLRL  KC
Sbjct: 1588 ERLRLSEKC 1596
>NP_001036040
          Length = 717

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+R G KC
Sbjct: 596 QRVRSGEKC 604
>NP_006050
          Length = 1575

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QRL  GA+C
Sbjct: 1095 QRLNKGARC 1103
>XP_005259266
          Length = 460

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 173 QRVHMGVKC 181
>XP_005259265
          Length = 482

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGVKC 203
>XP_006716984
          Length = 1259

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QRL  GA+C
Sbjct: 1095 QRLNKGARC 1103
>XP_005262700
          Length = 907

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           +RLRL  KC
Sbjct: 791 ERLRLSEKC 799
>XP_005262697
          Length = 1681

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +RLRL  KC
Sbjct: 1565 ERLRLSEKC 1573
>XP_006714054
          Length = 1693

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +RLRL  KC
Sbjct: 1577 ERLRLSEKC 1585
>XP_005262695
          Length = 1704

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +RLRL  KC
Sbjct: 1588 ERLRLSEKC 1596
>XP_006713677
          Length = 717

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+R G KC
Sbjct: 596 QRVRSGEKC 604
>NP_001123468
          Length = 491

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 204 QRVHMGVKC 212
>NP_037492
          Length = 451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 164 QRVHMGVKC 172
>NP_001138296
          Length = 700

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>NP_037530
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>NP_006621
          Length = 700

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>NP_037491
          Length = 617

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 217 QRVHMGEKC 225
>XP_005259278
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>XP_005259263
          Length = 617

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 217 QRVHMGEKC 225
>XP_006723038
          Length = 688

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 183 QRVHMGEKC 191
>XP_006723037
          Length = 700

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>XP_006723036
          Length = 700

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           QR+ +G KC
Sbjct: 195 QRVHMGEKC 203
>NP_940927
          Length = 1343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRLGAKC 9
           +RLGA+C
Sbjct: 403 MRLGAEC 409
>NP_002861
          Length = 203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           +RL LG KC
Sbjct: 115 ERLLLGNKC 123
>NP_001258967
          Length = 122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QRLRLGAKC 9
          +RL LG KC
Sbjct: 34 ERLLLGNKC 42
>NP_002966
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LRLG KC
Sbjct: 181 LRLGHKC 187
>XP_006720560
          Length = 1313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRLGAKC 9
           +RLGA+C
Sbjct: 403 MRLGAEC 409
>XP_005254961
          Length = 1342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRLGAKC 9
           +RLGA+C
Sbjct: 403 MRLGAEC 409
>XP_005254960
          Length = 1342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRLGAKC 9
           +RLGA+C
Sbjct: 403 MRLGAEC 409
>XP_005254959
          Length = 1343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRLGAKC 9
           +RLGA+C
Sbjct: 403 MRLGAEC 409
>NP_543139
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RLRLGAKC 9
           R RLG++C
Sbjct: 420 RARLGSRC 427
>NP_945339
          Length = 501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  RLRLGAKC 9
          R R GA+C
Sbjct: 53 RCRFGARC 60
>NP_005262
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   RLGAKC 9
           R GAKC
Sbjct: 322 RFGAKC 327
>NP_110394
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>NP_056997
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RLRLGAKC 9
          R RLGA C
Sbjct: 4  RPRLGATC 11
>NP_055713
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QRL +  KC
Sbjct: 289 QRLNIAEKC 297
>NP_065704
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QR+  G KC
Sbjct: 555 QRIHSGEKC 563
>NP_036216
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   RLGAKC 9
           R GAKC
Sbjct: 322 RFGAKC 327
>XP_005258722
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QRL +  KC
Sbjct: 288 QRLNIAEKC 296
>XP_006723152
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QRL +  KC
Sbjct: 289 QRLNIAEKC 297
>XP_006723151
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QRL +  KC
Sbjct: 291 QRLNIAEKC 299
>XP_006723150
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QRL +  KC
Sbjct: 292 QRLNIAEKC 300
>XP_005256800
          Length = 592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QR+  G KC
Sbjct: 386 QRIHSGEKC 394
>XP_006721624
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QRLRLGAKC 9
           QR+  G KC
Sbjct: 555 QRIHSGEKC 563
>XP_006717358
          Length = 831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252305
          Length = 1407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252303
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_006717357
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252304
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252302
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252301
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>XP_005252300
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLRLGAK 8
           +LRLGAK
Sbjct: 466 QLRLGAK 472
>NP_072088
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QRLRLGAKC 9
           ++ +LG KC
Sbjct: 212 EQFKLGVKC 220
>NP_004360
          Length = 3177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2756 QRVILQAKC 2764
>NP_877963
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+G +C
Sbjct: 357 LRMGCRC 363
>NP_476508
          Length = 2971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2550 QRVILQAKC 2558
>NP_002651
          Length = 1291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+G +C
Sbjct: 357 LRMGCRC 363
>NP_476507
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2149 QRVILQAKC 2157
>NP_002652
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+G +C
Sbjct: 349 LRMGCRC 355
>NP_997320
          Length = 4471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +R+RL A C
Sbjct: 2217 ERIRLQAHC 2225
>NP_612490
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+GA C
Sbjct: 695 LRVGATC 701
>XP_005261428
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+GA C
Sbjct: 695 LRVGATC 701
>XP_005261427
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+GA C
Sbjct: 695 LRVGATC 701
>XP_005260495
          Length = 1330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   LRLGAKC 9
           LR+G +C
Sbjct: 357 LRMGCRC 363
>XP_005253612
          Length = 4589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            +R+RL A C
Sbjct: 2335 ERIRLQAHC 2343
>XP_005246123
          Length = 2770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2349 QRVILQAKC 2357
>XP_005246122
          Length = 2977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2556 QRVILQAKC 2564
>XP_006712316
          Length = 3010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QRLRLGAKC 9
            QR+ L AKC
Sbjct: 2589 QRVILQAKC 2597
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.144    0.465 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 525,699
Number of extensions: 955
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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