Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_055921                                                              17    3301
XP_006713125                                                           17    3301
XP_006713124                                                           17    3301
NP_057308                                                              16    5631
NP_001034230                                                           16    5631
NP_653184                                                              16    5631
NP_001034451                                                           16    5631
XP_005267072                                                           16    5631
NP_060236                                                              16    7355
NP_001073312                                                           16    7355
NP_005157                                                              16    7355
NP_001019978                                                           16    7355
XP_005259656                                                           16    7355
XP_006710775                                                           16    7355
XP_005263536                                                           16    7355
NP_277052                                                              15    9605
NP_733936                                                              15    9605
NP_001071                                                              15    9605
NP_056099                                                              15    9605
NP_001272369                                                           15    9605
NP_689969                                                              15    9605
NP_001272368                                                           15    9605
NP_060481                                                              15    9605
NP_055951                                                              15    9605
NP_001172003                                                           15    9605
NP_001171988                                                           15    9605
NP_078893                                                              15    9605
NP_848613                                                              15    9605
NP_001264262                                                           15    9605
NP_001325                                                              15    9605
XP_003959998                                                           15    9605
XP_005256671                                                           15    9605
XP_005252265                                                           15    9605
XP_005252264                                                           15    9605
XP_006717348                                                           15    9605
XP_006717347                                                           15    9605
XP_006717346                                                           15    9605
XP_005248335                                                           15    9605
XP_006714526                                                           15    9605
XP_005265032                                                           15    9605
XP_005265031                                                           15    9605
XP_005265030                                                           15    9605
XP_006710565                                                           15    9605
XP_006710564                                                           15    9605
XP_005270743                                                           15    9605
NP_776246                                                              15    9605
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1235 QWDELARVL 1243
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1235 QWDELARVL 1243
>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1235 QWDELARVL 1243
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1232 QWDELARVL 1240
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1235 QWDELARVL 1243
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRDELARVL 9
            Q DELARVL
Sbjct: 1245 QWDELARVL 1253
>NP_055921
          Length = 1467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QRDELARVL 9
           QRD L RVL
Sbjct: 241 QRDALGRVL 249
>XP_006713125
          Length = 1467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QRDELARVL 9
           QRD L RVL
Sbjct: 241 QRDALGRVL 249
>XP_006713124
          Length = 1467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QRDELARVL 9
           QRD L RVL
Sbjct: 241 QRDALGRVL 249
>NP_057308
          Length = 595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRDELARVL 9
           +RDELA V+
Sbjct: 370 ERDELAGVM 378
>NP_001034230
          Length = 2365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RDELARVL 9
            RD+LAR L
Sbjct: 1602 RDDLARAL 1609
>NP_653184
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QRDELARVL 9
           +R+E+AR+L
Sbjct: 260 EREEMARLL 268
>NP_001034451
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QRDELARVL 9
           +R+E+AR+L
Sbjct: 260 EREEMARLL 268
>XP_005267072
          Length = 588

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRDELARVL 9
           +RDELA V+
Sbjct: 363 ERDELAGVM 371
>NP_060236
          Length = 1166

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RDELAR 7
           RDELAR
Sbjct: 197 RDELAR 202
>NP_001073312
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RDELAR 7
           RDELAR
Sbjct: 197 RDELAR 202
>NP_005157
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QRDELA 6
           QRDELA
Sbjct: 566 QRDELA 571
>NP_001019978
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QRDELA 6
           QRDELA
Sbjct: 567 QRDELA 572
>XP_005259656
          Length = 1373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QRDELA 6
            QRDELA
Sbjct: 1286 QRDELA 1291
>XP_006710775
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RDELAR 7
           RDELAR
Sbjct: 197 RDELAR 202
>XP_005263536
          Length = 1783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RDELAR 7
           RDELAR
Sbjct: 221 RDELAR 226
>NP_277052
          Length = 1731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RDELARV 8
            R+ELAR+
Sbjct: 1298 REELARI 1304
>NP_733936
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RDELARVL 9
           +D+LAR++
Sbjct: 135 KDDLARII 142
>NP_001071
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RDELARVL 9
           +D+LAR++
Sbjct: 135 KDDLARII 142
>NP_056099
          Length = 3375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    DELARVL 9
            DEL RVL
Sbjct: 2118 DELVRVL 2124
>NP_001272369
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RDELARVL 9
           RD LARV+
Sbjct: 424 RDGLARVI 431
>NP_689969
          Length = 1708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RDELARVL 9
           RD LARV+
Sbjct: 709 RDGLARVI 716
>NP_001272368
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RDELARVL 9
           RD LARV+
Sbjct: 709 RDGLARVI 716
>NP_060481
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRDELARVL 9
           +R+EL R+L
Sbjct: 197 KREELERIL 205
>NP_055951
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RDELARV 8
            +DELAR+
Sbjct: 1629 QDELARI 1635
>NP_001172003
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DELARVL 9
           +ELARVL
Sbjct: 845 EELARVL 851
>NP_001171988
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>NP_078893
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>NP_848613
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DELARVL 9
           DEL RVL
Sbjct: 439 DELGRVL 445
>NP_001264262
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDELARV 8
           RDE+AR+
Sbjct: 565 RDEIARL 571
>NP_001325
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QRDELARVL 9
           Q DE+A+ L
Sbjct: 227 QEDEMAKAL 235
>XP_003959998
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RDELARV 8
           RDE+AR+
Sbjct: 287 RDEIARL 293
>XP_005256671
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DELARVL 9
           DEL RVL
Sbjct: 439 DELGRVL 445
>XP_005252265
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>XP_005252264
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>XP_006717348
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>XP_006717347
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>XP_006717346
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DELARVL 9
            +ELARVL
Sbjct: 1081 EELARVL 1087
>XP_005248335
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RDELARVL 9
           RD LARV+
Sbjct: 424 RDGLARVI 431
>XP_006714526
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RDELARVL 9
           RD LARV+
Sbjct: 709 RDGLARVI 716
>XP_005265032
          Length = 2545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RDELARV 8
            +DELAR+
Sbjct: 1629 QDELARI 1635
>XP_005265031
          Length = 2569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RDELARV 8
            +DELAR+
Sbjct: 1629 QDELARI 1635
>XP_005265030
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RDELARV 8
            +DELAR+
Sbjct: 1629 QDELARI 1635
>XP_006710565
          Length = 3140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    DELARVL 9
            DEL RVL
Sbjct: 1883 DELVRVL 1889
>XP_006710564
          Length = 3432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    DELARVL 9
            DEL RVL
Sbjct: 2175 DELVRVL 2181
>XP_005270743
          Length = 3453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    DELARVL 9
            DEL RVL
Sbjct: 2196 DELVRVL 2202
>NP_776246
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  RDELARVL 9
          R ELARVL
Sbjct: 92 RCELARVL 99
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.140    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 438,058
Number of extensions: 702
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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