Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004201                                                              16    7355
XP_005270327                                                           16    7355
XP_005270326                                                           16    7355
NP_689846                                                              15    9605
NP_001018123                                                           15    9605
NP_001159921                                                           15    9605
NP_001258152                                                           15    9605
NP_055571                                                              15    9605
NP_001008938                                                           15    9605
NP_002209                                                              15    9605
NP_001092093                                                           15    9605
NP_005615                                                              15    9605
NP_001188288                                                           15    9605
XP_006711891                                                           15    9605
XP_006711888                                                           15    9605
XP_006711887                                                           15    9605
XP_005273364                                                           15    9605
XP_005273362                                                           15    9605
XP_005273361                                                           15    9605
XP_006711886                                                           15    9605
XP_006711885                                                           15    9605
XP_005273359                                                           15    9605
XP_006711884                                                           15    9605
XP_005273357                                                           15    9605
XP_005273356                                                           15    9605
XP_005273358                                                           15    9605
XP_005273355                                                           15    9605
XP_005273353                                                           15    9605
XP_005273352                                                           15    9605
XP_005273354                                                           15    9605
XP_005273349                                                           15    9605
XP_006711883                                                           15    9605
XP_005273350                                                           15    9605
XP_005273351                                                           15    9605
XP_006711882                                                           15    9605
XP_005273348                                                           15    9605
XP_005273346                                                           15    9605
XP_005273347                                                           15    9605
XP_005273345                                                           15    9605
XP_005273344                                                           15    9605
>NP_004201
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RAVQLVDS 9
           R VQL+DS
Sbjct: 211 RGVQLLDS 218
>XP_005270327
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RAVQLVDS 9
           R VQL+DS
Sbjct: 136 RGVQLLDS 143
>XP_005270326
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RAVQLVDS 9
           R VQL+DS
Sbjct: 194 RGVQLLDS 201
>NP_689846
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVQLVDS 9
           AVQL+DS
Sbjct: 286 AVQLMDS 292
>NP_001018123
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVQLVDS 9
           AVQL+DS
Sbjct: 286 AVQLMDS 292
>NP_001159921
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVQLVDS 9
           AVQL+DS
Sbjct: 359 AVQLLDS 365
>NP_001258152
          Length = 8923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7351 SVQLVDS 7357
>NP_055571
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRAVQLVD 8
           Q+AV+L+D
Sbjct: 624 QKAVELMD 631
>NP_001008938
          Length = 2032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRAVQLVD 8
           Q+AV+L+D
Sbjct: 624 QKAVELMD 631
>NP_002209
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AVQLVDS 9
           AVQL+DS
Sbjct: 359 AVQLLDS 365
>NP_001092093
          Length = 7968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 6394 SVQLVDS 6400
>NP_005615
          Length = 150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  QRAVQLVDS 9
          QRA++L+D+
Sbjct: 84 QRAMKLLDA 92
>NP_001188288
          Length = 149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  QRAVQLVDS 9
          QRA++L+D+
Sbjct: 84 QRAMKLLDA 92
>XP_006711891
          Length = 8925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7351 SVQLVDS 7357
>XP_006711888
          Length = 8059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 6485 SVQLVDS 6491
>XP_006711887
          Length = 8499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 6925 SVQLVDS 6931
>XP_005273364
          Length = 8653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7079 SVQLVDS 7085
>XP_005273362
          Length = 8675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7101 SVQLVDS 7107
>XP_005273361
          Length = 8763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7189 SVQLVDS 7195
>XP_006711886
          Length = 8833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7259 SVQLVDS 7265
>XP_006711885
          Length = 8835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7261 SVQLVDS 7267
>XP_005273359
          Length = 8843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7269 SVQLVDS 7275
>XP_006711884
          Length = 8847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7273 SVQLVDS 7279
>XP_005273357
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7277 SVQLVDS 7283
>XP_005273356
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7277 SVQLVDS 7283
>XP_005273358
          Length = 8851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7277 SVQLVDS 7283
>XP_005273355
          Length = 8924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7350 SVQLVDS 7356
>XP_005273353
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7361 SVQLVDS 7367
>XP_005273352
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7361 SVQLVDS 7367
>XP_005273354
          Length = 8935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7361 SVQLVDS 7367
>XP_005273349
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7365 SVQLVDS 7371
>XP_006711883
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7365 SVQLVDS 7371
>XP_005273350
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7365 SVQLVDS 7371
>XP_005273351
          Length = 8939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7365 SVQLVDS 7371
>XP_006711882
          Length = 8977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7403 SVQLVDS 7409
>XP_005273348
          Length = 9015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7441 SVQLVDS 7447
>XP_005273346
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7452 SVQLVDS 7458
>XP_005273347
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7452 SVQLVDS 7458
>XP_005273345
          Length = 9026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7452 SVQLVDS 7458
>XP_005273344
          Length = 9027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AVQLVDS 9
            +VQLVDS
Sbjct: 7453 SVQLVDS 7459
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.125    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 268,001
Number of extensions: 255
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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