Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     869
NP_848561                                                              17    4312
XP_005260809                                                           17    4312
XP_005260808                                                           17    4312
XP_005260807                                                           17    4312
NP_000146                                                              16    5631
NP_008958                                                              16    5631
NP_056131                                                              16    5631
NP_002421                                                              16    5631
XP_005267542                                                           16    5631
XP_005267541                                                           16    5631
XP_005267544                                                           16    5631
XP_005247133                                                           16    5631
NP_065190                                                              16    5631
NP_001254772                                                           16    7355
NP_004889                                                              16    7355
XP_006714117                                                           16    7355
XP_005265844                                                           16    7355
NP_078820                                                              15    9605
NP_001131022                                                           15    9605
NP_689975                                                              15    9605
XP_006712913                                                           15    9605
XP_005246195                                                           15    9605
XP_005246194                                                           15    9605
XP_006712912                                                           15    9605
XP_005246192                                                           15    9605
XP_005246191                                                           15    9605
XP_005246190                                                           15    9605
XP_006712911                                                           15    9605
XP_005246189                                                           15    9605
XP_006712910                                                           15    9605
XP_006712909                                                           15    9605
XP_005246187                                                           15    9605
XP_005246186                                                           15    9605
XP_006712908                                                           15    9605
XP_005246185                                                           15    9605
XP_006712907                                                           15    9605
XP_005246183                                                           15    9605
XP_005246182                                                           15    9605
XP_006712906                                                           15    9605
XP_005246181                                                           15    9605
XP_005246179                                                           15    9605
XP_005246178                                                           15    9605
XP_005246177                                                           15    9605
XP_005246176                                                           15    9605
XP_005246175                                                           15    9605
XP_006712905                                                           15    9605
XP_006712904                                                           15    9605
XP_005246174                                                           15    9605
XP_006712903                                                           15    9605
XP_005246173                                                           15    9605
XP_005246172                                                           15    9605
XP_005246171                                                           15    9605
XP_005246170                                                           15    9605
XP_005246169                                                           15    9605
>NP_115803
          Length = 1156

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QQRQQSSIS 9
           QQ+QQSSIS
Sbjct: 617 QQQQQSSIS 625

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QQRQQSSIS 9
           QQ+QQSSIS
Sbjct: 629 QQQQQSSIS 637
>NP_848561
          Length = 254

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  QQRQQSSIS 9
          QQ+Q+SSI+
Sbjct: 87 QQQQESSIN 95
>XP_005260809
          Length = 1832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQRQQSSI 8
            QQR QSS+
Sbjct: 1188 QQRDQSSV 1195
>XP_005260808
          Length = 1872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQRQQSSI 8
            QQR QSS+
Sbjct: 1228 QQRDQSSV 1235
>XP_005260807
          Length = 1883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQRQQSSI 8
            QQR QSS+
Sbjct: 1239 QQRDQSSV 1246
>NP_000146
          Length = 379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QQRQQSS 7
          QQRQQ+S
Sbjct: 9  QQRQQAS 15
>NP_008958
          Length = 1522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQRQQSSI 8
            QQRQ+S I
Sbjct: 1382 QQRQESGI 1389
>NP_056131
          Length = 1090

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQRQQSSIS 9
           ++RQQ SIS
Sbjct: 163 ERRQQQSIS 171
>NP_002421
          Length = 1320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    QRQQSSIS 9
            QRQQ SIS
Sbjct: 1163 QRQQFSIS 1170
>XP_005267542
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQRQQSSIS 9
           ++RQQ SIS
Sbjct: 160 ERRQQQSIS 168
>XP_005267541
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQRQQSSIS 9
           ++RQQ SIS
Sbjct: 160 ERRQQQSIS 168
>XP_005267544
          Length = 1158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQRQQSSIS 9
           ++RQQ SIS
Sbjct: 231 ERRQQQSIS 239
>XP_005247133
          Length = 1517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQRQQSSI 8
            QQRQ+S I
Sbjct: 1377 QQRQESGI 1384
>NP_065190
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QQRQQSSIS 9
           QQ+QQSS S
Sbjct: 128 QQQQQSSPS 136
>NP_001254772
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQRQQSS 7
           QQ+QQSS
Sbjct: 756 QQQQQSS 762
>NP_004889
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQRQQSS 7
           QQ+QQSS
Sbjct: 756 QQQQQSS 762
>XP_006714117
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQRQQSS 7
           QQ+QQSS
Sbjct: 756 QQQQQSS 762
>XP_005265844
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQRQQSS 7
           QQ+QQSS
Sbjct: 756 QQQQQSS 762
>NP_078820
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QRQQSSI 8
           QRQ+SS+
Sbjct: 231 QRQESSV 237
>NP_001131022
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 383 QQKQASSI 390
>NP_689975
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QQRQQSS 7
          QQR QSS
Sbjct: 64 QQRSQSS 70
>XP_006712913
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 391 QQKQASSI 398
>XP_005246195
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 404 QQKQASSI 411
>XP_005246194
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 404 QQKQASSI 411
>XP_006712912
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 194 QQKQASSI 201
>XP_005246192
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 199 QQKQASSI 206
>XP_005246191
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 209 QQKQASSI 216
>XP_005246190
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 223 QQKQASSI 230
>XP_006712911
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 231 QQKQASSI 238
>XP_005246189
          Length = 848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 233 QQKQASSI 240
>XP_006712910
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 255 QQKQASSI 262
>XP_006712909
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 275 QQKQASSI 282
>XP_005246187
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 287 QQKQASSI 294
>XP_005246186
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 296 QQKQASSI 303
>XP_006712908
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 307 QQKQASSI 314
>XP_005246185
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 309 QQKQASSI 316
>XP_006712907
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 313 QQKQASSI 320
>XP_005246183
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 320 QQKQASSI 327
>XP_005246182
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 333 QQKQASSI 340
>XP_006712906
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 335 QQKQASSI 342
>XP_005246181
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 340 QQKQASSI 347
>XP_005246179
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 346 QQKQASSI 353
>XP_005246178
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 350 QQKQASSI 357
>XP_005246177
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 355 QQKQASSI 362
>XP_005246176
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 367 QQKQASSI 374
>XP_005246175
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 368 QQKQASSI 375
>XP_006712905
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 370 QQKQASSI 377
>XP_006712904
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 372 QQKQASSI 379
>XP_005246174
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 380 QQKQASSI 387
>XP_006712903
          Length = 997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 382 QQKQASSI 389
>XP_005246173
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 383 QQKQASSI 390
>XP_005246172
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 389 QQKQASSI 396
>XP_005246171
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 391 QQKQASSI 398
>XP_005246170
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 394 QQKQASSI 401
>XP_005246169
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQRQQSSI 8
           QQ+Q SSI
Sbjct: 404 QQKQASSI 411
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293   0.0984    0.207 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,563
Number of extensions: 672
Number of successful extensions: 56
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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