Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     869
NP_001091680                                                           19     869
NP_001091679                                                           19     869
XP_006713048                                                           19     869
XP_006713047                                                           19     869
XP_006713046                                                           19     869
XP_005264943                                                           19     869
NP_001277114                                                           17    3301
NP_068375                                                              17    3301
NP_004870                                                              17    4312
NP_001277064                                                           17    4312
NP_619639                                                              16    5631
NP_733842                                                              16    5631
NP_060768                                                              16    5631
NP_001240622                                                           16    5631
XP_006710815                                                           16    5631
XP_006710814                                                           16    5631
XP_005271060                                                           16    5631
XP_006710813                                                           16    5631
NP_064529                                                              16    5631
NP_660187                                                              16    7355
NP_149163                                                              16    7355
NP_115972                                                              16    7355
NP_001274433                                                           16    7355
NP_002262                                                              16    7355
NP_848639                                                              16    7355
NP_001138492                                                           16    7355
NP_001229488                                                           16    7355
XP_005258911                                                           16    7355
XP_005258910                                                           16    7355
XP_005254110                                                           16    7355
XP_005254109                                                           16    7355
XP_005254106                                                           16    7355
XP_006715151                                                           16    7355
XP_006712932                                                           16    7355
XP_005264128                                                           16    7355
XP_005264121                                                           16    7355
XP_005264120                                                           16    7355
XP_005264119                                                           16    7355
XP_005264115                                                           16    7355
XP_005264114                                                           16    7355
XP_005264113                                                           16    7355
XP_005264112                                                           16    7355
XP_005264111                                                           16    7355
XP_005264110                                                           16    7355
XP_005264109                                                           16    7355
XP_005264107                                                           16    7355
XP_006712927                                                           16    7355
XP_005264105                                                           16    7355
XP_005264104                                                           16    7355
XP_005264103                                                           16    7355
XP_005264102                                                           16    7355
XP_005264101                                                           16    7355
XP_005246870                                                           16    7355
XP_005246869                                                           16    7355
NP_001123917                                                           16    7355
NP_001274432                                                           16    7355
NP_006742                                                              16    7355
NP_001726                                                              15    9605
NP_002378                                                              15    9605
NP_001078846                                                           15    9605
NP_056100                                                              15    9605
NP_443066                                                              15    9605
NP_997289                                                              15    9605
XP_006722494                                                           15    9605
XP_005250956                                                           15    9605
XP_005272048                                                           15    9605
XP_006714680                                                           15    9605
XP_006714302                                                           15    9605
XP_005263127                                                           15    9605
NP_001153019                                                           15    9605
NP_000828                                                              15    9605
NP_001009184                                                           15    9605
NP_061908                                                              15    9605
>NP_001895
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 26 QQQSYLDSG 34
>NP_001091680
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 26 QQQSYLDSG 34
>NP_001091679
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 26 QQQSYLDSG 34
>XP_006713048
          Length = 720

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 26 QQQSYLDSG 34
>XP_006713047
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 19 QQQSYLDSG 27
>XP_006713046
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 19 QQQSYLDSG 27
>XP_005264943
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQQSYLVSG 9
          QQQSYL SG
Sbjct: 26 QQQSYLDSG 34
>NP_001277114
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QSYLVSG 9
           QSY+VSG
Sbjct: 202 QSYIVSG 208
>NP_068375
          Length = 941

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QSYLVSG 9
           QSY+VSG
Sbjct: 212 QSYIVSG 218
>NP_004870
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QQSYLVSG 9
           Q SY++SG
Sbjct: 256 QSSYIISG 263
>NP_001277064
          Length = 326

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QQSYLVSG 9
           Q SY++SG
Sbjct: 242 QSSYIISG 249
>NP_619639
          Length = 4074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QQQSYLVSG 9
            +Q +YLVSG
Sbjct: 2697 RQLTYLVSG 2705
>NP_733842
          Length = 3396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QQQSYLVSG 9
            +Q +YLVSG
Sbjct: 2697 RQLTYLVSG 2705
>NP_060768
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 468 QQKSYLV 474
>NP_001240622
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 412 QQKSYLV 418
>XP_006710815
          Length = 386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 301 QQKSYLV 307
>XP_006710814
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 468 QQKSYLV 474
>XP_005271060
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 468 QQKSYLV 474
>XP_006710813
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQ+SYLV
Sbjct: 468 QQKSYLV 474
>NP_064529
          Length = 637

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           QQQ+YL+
Sbjct: 630 QQQTYLI 636
>NP_660187
          Length = 1344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQSYLVSG 9
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_149163
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQSYLVSG 9
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_115972
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQSYLVSG 9
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_001274433
          Length = 1084

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQQSYLVS 8
           Q+QSYL S
Sbjct: 901 QEQSYLKS 908
>NP_002262
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          QQQ YL+ G
Sbjct: 26 QQQFYLLLG 34
>NP_848639
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSYL+
Sbjct: 227 RQQSYLI 233
>NP_001138492
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          Q  SYL+SG
Sbjct: 50 QHGSYLLSG 58
>NP_001229488
          Length = 1239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005258911
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSYL+
Sbjct: 189 RQQSYLI 195
>XP_005258910
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSYL+
Sbjct: 201 RQQSYLI 207
>XP_005254110
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          QQQ YL+ G
Sbjct: 26 QQQFYLLLG 34
>XP_005254109
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          QQQ YL+ G
Sbjct: 26 QQQFYLLLG 34
>XP_005254106
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          QQQ YL+ G
Sbjct: 26 QQQFYLLLG 34
>XP_006715151
          Length = 182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QQQSYLVSG 9
          Q  SYL+SG
Sbjct: 50 QHGSYLLSG 58
>XP_006712932
          Length = 1189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264128
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264121
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264120
          Length = 1260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264119
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264115
          Length = 1312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264114
          Length = 1315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264113
          Length = 1317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264112
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264111
          Length = 1325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264110
          Length = 1328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264109
          Length = 1337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264107
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_006712927
          Length = 1372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 496 QEQAYLLS 503
>XP_005264105
          Length = 1384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264104
          Length = 1389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264103
          Length = 1390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264102
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005264101
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQQSYLVS 8
           Q+Q+YL+S
Sbjct: 516 QEQAYLLS 523
>XP_005246870
          Length = 1252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQQSYLVS 8
            Q+QSYL S
Sbjct: 1072 QEQSYLKS 1079
>XP_005246869
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQQSYLVS 8
            Q+QSYL S
Sbjct: 1072 QEQSYLKS 1079
>NP_001123917
          Length = 1259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQQSYLVS 8
            Q+QSYL S
Sbjct: 1076 QEQSYLKS 1083
>NP_001274432
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQQSYLVS 8
            Q+QSYL S
Sbjct: 1054 QEQSYLKS 1061
>NP_006742
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQQSYLVS 8
            Q+QSYL S
Sbjct: 1076 QEQSYLKS 1083
>NP_001726
          Length = 1676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QQQSYLVS 8
          Q+Q+Y++S
Sbjct: 19 QEQTYVIS 26
>NP_002378
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           Q+Q+YLV
Sbjct: 656 QEQAYLV 662
>NP_001078846
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           Q+Q+YLV
Sbjct: 846 QEQAYLV 852
>NP_056100
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QSYLVSG 9
           Q YL+SG
Sbjct: 482 QRYLISG 488
>NP_443066
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QSYLVSG 9
           Q YL+SG
Sbjct: 482 QRYLISG 488
>NP_997289
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QSYLVSG 9
           Q+YL+SG
Sbjct: 254 QNYLLSG 260
>XP_006722494
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QSYLVSG 9
           Q YL+SG
Sbjct: 482 QRYLISG 488
>XP_005250956
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QQSYLVSG 9
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>XP_005272048
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           Q+Q+YLV
Sbjct: 656 QEQAYLV 662
>XP_006714680
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           Q+Q+YLV
Sbjct: 807 QEQAYLV 813
>XP_006714302
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSY++
Sbjct: 247 EQQSYII 253
>XP_005263127
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSY++
Sbjct: 247 EQQSYII 253
>NP_001153019
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QSYLVSG 9
           Q+YL+SG
Sbjct: 254 QNYLLSG 260
>NP_000828
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QQSYLVSG 9
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>NP_001009184
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QQSYLVSG 9
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>NP_061908
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QQQSYLV 7
           +QQSY++
Sbjct: 247 EQQSYII 253
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.119    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 528,576
Number of extensions: 890
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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