Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_775919                                                              17    2528
XP_006712503                                                           17    2528
NP_001364                                                              17    4312
NP_071330                                                              17    4312
XP_005252886                                                           17    4312
XP_006711798                                                           17    4312
NP_055870                                                              17    4312
NP_001191762                                                           16    5631
NP_001191763                                                           16    5631
NP_060545                                                              16    5631
NP_001191761                                                           16    5631
NP_705618                                                              16    5631
NP_004289                                                              16    5631
NP_001073970                                                           16    5631
NP_003280                                                              16    7355
NP_001158187                                                           16    7355
NP_694558                                                              16    7355
NP_001274270                                                           16    7355
NP_001078880                                                           16    7355
NP_001274269                                                           16    7355
NP_060988                                                              16    7355
NP_877428                                                              16    7355
NP_899061                                                              16    7355
NP_003413                                                              16    7355
NP_932172                                                              16    7355
XP_006723423                                                           16    7355
XP_006723422                                                           16    7355
XP_006723421                                                           16    7355
XP_005259261                                                           16    7355
XP_005259260                                                           16    7355
XP_005251627                                                           16    7355
XP_005251625                                                           16    7355
XP_005248298                                                           16    7355
NP_699195                                                              15    9605
NP_001264220                                                           15    9605
NP_036552                                                              15    9605
NP_775835                                                              15    9605
NP_689997                                                              15    9605
NP_056073                                                              15    9605
NP_001157945                                                           15    9605
NP_064569                                                              15    9605
NP_057107                                                              15    9605
NP_061743                                                              15    9605
NP_919278                                                              15    9605
NP_114476                                                              15    9605
NP_060207                                                              15    9605
NP_001020119                                                           15    9605
XP_006719797                                                           15    9605
XP_006717082                                                           15    9605
XP_006717081                                                           15    9605
XP_005250285                                                           15    9605
XP_006715971                                                           15    9605
XP_006715970                                                           15    9605
XP_005263972                                                           15    9605
XP_005263971                                                           15    9605
XP_006712459                                                           15    9605
XP_006710770                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            QQLKITT N
Sbjct: 2306 QQLKITTDN 2314
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            QQLKITT N
Sbjct: 2298 QQLKITTDN 2306
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            QQLKITT N
Sbjct: 2259 QQLKITTDN 2267
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            QQLKITT N
Sbjct: 2338 QQLKITTDN 2346
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            QQLKITT N
Sbjct: 2351 QQLKITTDN 2359
>NP_775919
          Length = 1530

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQLKITTHN 9
           +QLK T+HN
Sbjct: 689 EQLKKTSHN 697
>XP_006712503
          Length = 1470

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QQLKITTHN 9
           +QLK T+HN
Sbjct: 629 EQLKKTSHN 637
>NP_001364
          Length = 4515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            Q+LK TTH+
Sbjct: 3845 QELKGTTHH 3853
>NP_071330
          Length = 631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QLKITTHN 9
          QLK+ +HN
Sbjct: 30 QLKVLSHN 37
>XP_005252886
          Length = 527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QLKITTHN 9
          QLK+ +HN
Sbjct: 31 QLKVLSHN 38
>XP_006711798
          Length = 4586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QQLKITTHN 9
            Q+LK TTH+
Sbjct: 3907 QELKGTTHH 3915
>NP_055870
          Length = 585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QLKITTHN 9
          QLK+ +HN
Sbjct: 31 QLKVLSHN 38
>NP_001191762
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           QQ+K+ T N
Sbjct: 527 QQMKLVTEN 535
>NP_001191763
          Length = 470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           QQ+K+ T N
Sbjct: 448 QQMKLVTEN 456
>NP_060545
          Length = 660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           QQ+K+ T N
Sbjct: 638 QQMKLVTEN 646
>NP_001191761
          Length = 594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           QQ+K+ T N
Sbjct: 572 QQMKLVTEN 580
>NP_705618
          Length = 1391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQLKITT 7
           +QLKITT
Sbjct: 816 EQLKITT 822
>NP_004289
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QQLKITT 7
           +QLKITT
Sbjct: 757 EQLKITT 763
>NP_001073970
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           QQ+ +TTH
Sbjct: 131 QQVTLTTH 138
>NP_003280
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQLKITTHN 9
           ++LKI T+N
Sbjct: 195 EELKIVTNN 203
>NP_001158187
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+ TH
Sbjct: 323 QKLKLITH 330
>NP_694558
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  QQLKITTHN 9
          QQL +  HN
Sbjct: 78 QQLSLNQHN 86
>NP_001274270
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  QQLKITTHN 9
          QQL +  HN
Sbjct: 78 QQLSLNQHN 86
>NP_001078880
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QQLKITTHN 9
           QQL +  HN
Sbjct: 241 QQLSLNQHN 249
>NP_001274269
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  QQLKITTHN 9
          QQL +  HN
Sbjct: 78 QQLSLNQHN 86
>NP_060988
          Length = 874

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQLKITT 7
           +QLK+TT
Sbjct: 131 EQLKVTT 137
>NP_877428
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQLKITT 7
           +QLK+TT
Sbjct: 131 EQLKVTT 137
>NP_899061
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+ TH
Sbjct: 292 QKLKLITH 299
>NP_003413
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 608 QRLKLTRH 615
>NP_932172
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 608 QRLKLTRH 615
>XP_006723423
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 608 QRLKLTRH 615
>XP_006723422
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 608 QRLKLTRH 615
>XP_006723421
          Length = 719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 593 QRLKLTRH 600
>XP_005259261
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 649 QRLKLTRH 656
>XP_005259260
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQLKITTH 8
           Q+LK+T H
Sbjct: 649 QRLKLTRH 656
>XP_005251627
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQLKITTHN 9
           ++LKI T+N
Sbjct: 195 EELKIVTNN 203
>XP_005251625
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQLKITTHN 9
           ++LKI T+N
Sbjct: 195 EELKIVTNN 203
>XP_005248298
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QQLKITTHN 9
           QQL +  HN
Sbjct: 241 QQLSLNQHN 249
>NP_699195
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LKITTHN 9
           +KIT HN
Sbjct: 126 VKITIHN 132
>NP_001264220
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           + +K+T HN
Sbjct: 139 KMIKLTMHN 147
>NP_036552
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QLKITTHN 9
           Q+K  THN
Sbjct: 299 QIKKATHN 306
>NP_775835
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LKITTHN 9
           +K+TTH+
Sbjct: 467 VKVTTHS 473
>NP_689997
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QLKITTHN 9
           + KIT HN
Sbjct: 291 EAKITIHN 298
>NP_056073
          Length = 1219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLKITTH 8
           QLK+T H
Sbjct: 656 QLKMTAH 662
>NP_001157945
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QQLKITTH 8
           QQL + TH
Sbjct: 173 QQLNLRTH 180
>NP_064569
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QQLKITTHN 9
           Q+LK   HN
Sbjct: 586 QELKFDEHN 594
>NP_057107
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QQLKITT 7
           +QLK+TT
Sbjct: 98  EQLKLTT 104
>NP_061743
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QLKITTHN 9
           QL++T H+
Sbjct: 529 QLRVTAHD 536
>NP_919278
          Length = 1925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLKITTH 8
           QLK+ TH
Sbjct: 877 QLKLDTH 883
>NP_114476
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QLKITTHN 9
           QL++T H+
Sbjct: 529 QLRVTAHD 536
>NP_060207
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QQLKITTH 8
           QQL + TH
Sbjct: 173 QQLNLRTH 180
>NP_001020119
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QQLKITTH 8
           QQL + TH
Sbjct: 173 QQLNLRTH 180
>XP_006719797
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   QQLKITTHN 9
           + +K+T HN
Sbjct: 139 KMIKLTMHN 147
>XP_006717082
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLKITTH 8
           QLK+T H
Sbjct: 588 QLKMTAH 594
>XP_006717081
          Length = 1209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLKITTH 8
           QLK+T H
Sbjct: 646 QLKMTAH 652
>XP_005250285
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LKITTHN 9
           +K+TTH+
Sbjct: 467 VKVTTHS 473
>XP_006715971
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LKITTHN 9
           +K+TTH+
Sbjct: 467 VKVTTHS 473
>XP_006715970
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LKITTHN 9
           +K+TTH+
Sbjct: 467 VKVTTHS 473
>XP_005263972
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QQLKITTHN 9
           Q+LK   HN
Sbjct: 586 QELKFDEHN 594
>XP_005263971
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QQLKITTHN 9
           Q+LK   HN
Sbjct: 586 QELKFDEHN 594
>XP_006712459
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QLKITTH 8
           QLK+ TH
Sbjct: 866 QLKLDTH 872
>XP_006710770
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   QQLKITTH 8
           QQL + TH
Sbjct: 155 QQLNLRTH 162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.119    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 500,803
Number of extensions: 850
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package