Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     299
NP_653080                                                              20     299
XP_005267292                                                           20     299
XP_005267291                                                           20     299
XP_005267290                                                           20     299
XP_005265921                                                           17    3301
XP_006714900                                                           17    3301
XP_005265917                                                           17    3301
NP_005520                                                              17    4312
XP_006710661                                                           17    4312
XP_005245920                                                           17    4312
XP_006710660                                                           17    4312
XP_006710659                                                           17    4312
XP_006710658                                                           17    4312
XP_006710657                                                           17    4312
NP_775819                                                              16    5631
NP_065134                                                              16    5631
NP_060077                                                              16    5631
XP_006726681                                                           16    5631
XP_006726680                                                           16    5631
XP_005258688                                                           16    5631
XP_005258687                                                           16    5631
XP_005258685                                                           16    5631
XP_005269094                                                           16    5631
NP_000419                                                              16    7355
NP_005198                                                              16    7355
NP_001120936                                                           16    7355
NP_001123230                                                           16    7355
NP_115797                                                              16    7355
NP_003379                                                              16    7355
NP_071752                                                              16    7355
NP_001278327                                                           15    9605
NP_001005751                                                           15    9605
NP_001104777                                                           15    9605
NP_031371                                                              15    9605
NP_542780                                                              15    9605
NP_473366                                                              15    9605
NP_006101                                                              15    9605
NP_115635                                                              15    9605
NP_079527                                                              15    9605
NP_001162578                                                           15    9605
NP_061114                                                              15    9605
NP_001230575                                                           15    9605
NP_001032238                                                           15    9605
NP_006812                                                              15    9605
XP_005266819                                                           15    9605
XP_006722604                                                           15    9605
XP_006720070                                                           15    9605
XP_005271567                                                           15    9605
XP_005271566                                                           15    9605
XP_005271565                                                           15    9605
XP_005271564                                                           15    9605
XP_005271563                                                           15    9605
XP_005271892                                                           15    9605
XP_006718078                                                           15    9605
XP_005271890                                                           15    9605
XP_006718077                                                           15    9605
XP_006718076                                                           15    9605
XP_006717895                                                           15    9605
XP_005269865                                                           15    9605
XP_006717894                                                           15    9605
XP_005269864                                                           15    9605
XP_005269863                                                           15    9605
XP_006716724                                                           15    9605
XP_005272401                                                           15    9605
XP_006715409                                                           15    9605
NP_114412                                                              15    9605
NP_001162577                                                           15    9605
NP_056077                                                              15    9605
>NP_005091
          Length = 1782

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QPVQRAEAQ 9
            QPVQRAEA+
Sbjct: 1067 QPVQRAEAE 1075
>NP_653080
          Length = 1684

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QPVQRAEAQ 9
           QPVQRAEA+
Sbjct: 969 QPVQRAEAE 977
>XP_005267292
          Length = 1677

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QPVQRAEAQ 9
           QPVQRAEA+
Sbjct: 962 QPVQRAEAE 970
>XP_005267291
          Length = 1684

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QPVQRAEAQ 9
           QPVQRAEA+
Sbjct: 969 QPVQRAEAE 977
>XP_005267290
          Length = 1782

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QPVQRAEAQ 9
            QPVQRAEA+
Sbjct: 1067 QPVQRAEAE 1075
>XP_005265921
          Length = 257

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QPVQRAEAQ 9
          QPV R EAQ
Sbjct: 52 QPVGREEAQ 60
>XP_006714900
          Length = 319

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QPVQRAEAQ 9
          QPV R EAQ
Sbjct: 52 QPVGREEAQ 60
>XP_005265917
          Length = 335

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QPVQRAEAQ 9
          QPV R EAQ
Sbjct: 52 QPVGREEAQ 60
>NP_005520
          Length = 4391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 675 RPVQRAE 681
>XP_006710661
          Length = 4057

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 693 RPVQRAE 699
>XP_005245920
          Length = 4392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 676 RPVQRAE 682
>XP_006710660
          Length = 4397

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 675 RPVQRAE 681
>XP_006710659
          Length = 4556

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 693 RPVQRAE 699
>XP_006710658
          Length = 4563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 676 RPVQRAE 682
>XP_006710657
          Length = 4579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQRAE
Sbjct: 692 RPVQRAE 698
>NP_775819
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PVQRAEAQ 9
          PV RAEA+
Sbjct: 85 PVSRAEAR 92
>NP_065134
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PVQRAEA 8
           P QRAEA
Sbjct: 682 PAQRAEA 688
>NP_060077
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PVQRAEA 8
           P QRAEA
Sbjct: 605 PAQRAEA 611
>XP_006726681
          Length = 336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  PVQRAEAQ 9
          P++RA+AQ
Sbjct: 52 PLERADAQ 59
>XP_006726680
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  PVQRAEAQ 9
          P++RA+AQ
Sbjct: 52 PLERADAQ 59
>XP_005258688
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PVQRAEAQ 9
          PV RAEA+
Sbjct: 77 PVSRAEAR 84
>XP_005258687
          Length = 153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PVQRAEAQ 9
          PV RAEA+
Sbjct: 85 PVSRAEAR 92
>XP_005258685
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PVQRAEAQ 9
          PV RAEA+
Sbjct: 77 PVSRAEAR 84
>XP_005269094
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PVQRAEA 8
           P QRAEA
Sbjct: 662 PAQRAEA 668
>NP_000419
          Length = 1821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QPVQRAE 7
          QPV+RA+
Sbjct: 83 QPVERAQ 89
>NP_005198
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  PVQRAEAQ 9
          PV R EAQ
Sbjct: 18 PVSRQEAQ 25
>NP_001120936
          Length = 3925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QPVQRAEA 8
            QPVQ+A A
Sbjct: 1667 QPVQKAGA 1674
>NP_001123230
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QPVQRAE 7
          QPV RAE
Sbjct: 56 QPVTRAE 62
>NP_115797
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VQRAEAQ 9
           +QRAEAQ
Sbjct: 734 LQRAEAQ 740
>NP_003379
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VQRAEAQ 9
           +QRAEAQ
Sbjct: 769 LQRAEAQ 775
>NP_071752
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QPVQRAE 7
          QPV RAE
Sbjct: 56 QPVTRAE 62
>NP_001278327
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 106 EPVLKAEAE 114
>NP_001005751
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 106 EPVLKAEAE 114
>NP_001104777
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QPVQRAEA 8
          +P++RA+A
Sbjct: 63 RPIERADA 70
>NP_031371
          Length = 1845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           P+Q+ EAQ
Sbjct: 334 PLQQTEAQ 341
>NP_542780
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QPVQRAE 7
          +PVQ+AE
Sbjct: 91 RPVQKAE 97
>NP_473366
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 95  RPVQKAE 101
>NP_006101
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PVQRAEAQ 9
           P QR EA+
Sbjct: 265 PTQRGEAE 272
>NP_115635
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QPVQRAEAQ 9
           QPV+RA  +
Sbjct: 333 QPVERANPE 341
>NP_079527
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           PV+RAE +
Sbjct: 535 PVKRAEGE 542
>NP_001162578
          Length = 1245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 106 EPVLKAEAE 114
>NP_061114
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 95  RPVQKAE 101
>NP_001230575
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PVQRAEAQ 9
           P QR EA+
Sbjct: 265 PTQRGEAE 272
>NP_001032238
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PVQRAEA 8
           PV+RAE+
Sbjct: 310 PVERAES 316
>NP_006812
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PVQRAEA 8
           PV+RAE+
Sbjct: 372 PVERAES 378
>XP_005266819
          Length = 1790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           P+Q+ EAQ
Sbjct: 279 PLQQTEAQ 286
>XP_006722604
          Length = 1847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           P+Q+ EAQ
Sbjct: 336 PLQQTEAQ 343
>XP_006720070
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   PVQRAEA 8
           PV+RAE+
Sbjct: 175 PVERAES 181
>XP_005271567
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 108 RPVQKAE 114
>XP_005271566
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 108 RPVQKAE 114
>XP_005271565
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 108 RPVQKAE 114
>XP_005271564
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 108 RPVQKAE 114
>XP_005271563
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QPVQRAE 7
           +PVQ+AE
Sbjct: 108 RPVQKAE 114
>XP_005271892
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QPVQRAEA 8
          QPV +AE+
Sbjct: 50 QPVHKAES 57
>XP_006718078
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QPVQRAEA 8
           QPV +AE+
Sbjct: 154 QPVHKAES 161
>XP_005271890
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QPVQRAEA 8
           QPV +AE+
Sbjct: 139 QPVHKAES 146
>XP_006718077
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QPVQRAEA 8
           QPV +AE+
Sbjct: 143 QPVHKAES 150
>XP_006718076
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QPVQRAEA 8
           QPV +AE+
Sbjct: 154 QPVHKAES 161
>XP_006717895
          Length = 1297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 158 EPVLKAEAE 166
>XP_005269865
          Length = 1331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 158 EPVLKAEAE 166
>XP_006717894
          Length = 1342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 158 EPVLKAEAE 166
>XP_005269864
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 158 EPVLKAEAE 166
>XP_005269863
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 158 EPVLKAEAE 166
>XP_006716724
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           PV+RAE +
Sbjct: 391 PVKRAEGE 398
>XP_005272401
          Length = 1083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PVQRAEAQ 9
           PV+RAE +
Sbjct: 535 PVKRAEGE 542
>XP_006715409
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QPVQRAE 7
          +PVQ+AE
Sbjct: 91 RPVQKAE 97
>NP_114412
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QPVQRAEA 8
           QPV +AE+
Sbjct: 112 QPVHKAES 119
>NP_001162577
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 106 EPVLKAEAE 114
>NP_056077
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QPVQRAEAQ 9
           +PV +AEA+
Sbjct: 106 EPVLKAEAE 114
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.113    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,535
Number of extensions: 939
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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