Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     869
NP_001185763                                                           19     869
NP_055459                                                              19     869
NP_001002811                                                           19     869
NP_001002812                                                           19     869
XP_006726410                                                           19     869
XP_006711719                                                           19     869
XP_006711717                                                           19     869
XP_006711716                                                           19     869
XP_006711715                                                           19     869
XP_006711714                                                           19     869
XP_006711713                                                           19     869
XP_006711712                                                           19     869
XP_006711711                                                           19     869
XP_006711710                                                           19     869
XP_006711709                                                           19     869
XP_005277503                                                           19     869
XP_005273038                                                           19     869
XP_006711708                                                           19     869
XP_005277500                                                           19     869
XP_006711707                                                           19     869
XP_005277499                                                           19     869
XP_006711706                                                           19     869
XP_006711705                                                           19     869
XP_006711164                                                           19     869
NP_775321                                                              17    2528
NP_001106649                                                           17    2528
NP_619728                                                              17    2528
NP_006590                                                              17    2528
NP_619727                                                              17    2528
NP_775322                                                              17    2528
XP_005255834                                                           17    2528
XP_006721188                                                           17    2528
NP_006176                                                              17    4312
NP_001273490                                                           17    4312
XP_006718633                                                           17    4312
XP_006718632                                                           17    4312
XP_006718631                                                           17    4312
XP_006718630                                                           17    4312
XP_006718629                                                           17    4312
XP_006718628                                                           17    4312
XP_006718627                                                           17    4312
XP_006718626                                                           17    4312
XP_006718625                                                           17    4312
NP_057302                                                              16    5631
XP_005248593                                                           16    5631
XP_006714713                                                           16    5631
XP_005248591                                                           16    5631
XP_006726692                                                           16    7355
XP_006721060                                                           16    7355
XP_006710063                                                           16    7355
NP_079197                                                              15    9605
NP_057595                                                              15    9605
NP_066288                                                              15    9605
NP_055108                                                              15    9605
XP_005262260                                                           15    9605
XP_005262259                                                           15    9605
XP_006723242                                                           15    9605
XP_005258889                                                           15    9605
XP_005253440                                                           15    9605
NP_976219                                                              15    9605
NP_037500                                                              15    9605
NP_689759                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>NP_001185763
          Length = 2362

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 412 QNKSQQLRA 420
>NP_055459
          Length = 2346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 412 QNKSQQLRA 420
>NP_001002811
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>NP_001002812
          Length = 969

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 412 QNKSQQLRA 420
>XP_006726410
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 487 QNKSQQLRA 495
>XP_006711719
          Length = 2302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>XP_006711717
          Length = 2385

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>XP_006711716
          Length = 2411

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>XP_006711715
          Length = 2428

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 412 QNKSQQLRA 420
>XP_006711714
          Length = 2429

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 412 QNKSQQLRA 420
>XP_006711713
          Length = 2432

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 415 QNKSQQLRA 423
>XP_006711712
          Length = 2473

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711711
          Length = 2482

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711710
          Length = 2494

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>XP_006711709
          Length = 2495

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 478 QNKSQQLRA 486
>XP_005277503
          Length = 2498

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_005273038
          Length = 2509

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711708
          Length = 2512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_005277500
          Length = 2525

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711707
          Length = 2553

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_005277499
          Length = 2561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711706
          Length = 2591

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711705
          Length = 2592

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 575 QNKSQQLRA 583
>XP_006711164
          Length = 2087

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QN SQQLRA
Sbjct: 487 QNKSQQLRA 495
>NP_775321
          Length = 1455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 696 QNTIQQLQA 704
>NP_001106649
          Length = 1548

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 789 QNTIQQLQA 797
>NP_619728
          Length = 1455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 696 QNTIQQLQA 704
>NP_006590
          Length = 1531

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 772 QNTIQQLQA 780
>NP_619727
          Length = 1549

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 790 QNTIQQLQA 798
>NP_775322
          Length = 1455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 696 QNTIQQLQA 704
>XP_005255834
          Length = 1264

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 505 QNTIQQLQA 513
>XP_006721188
          Length = 1484

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNTSQQLRA 9
           QNT QQL+A
Sbjct: 725 QNTIQQLQA 733
>NP_006176
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>NP_001273490
          Length = 2101

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718633
          Length = 2101

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718632
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718631
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718630
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718629
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718628
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718627
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718626
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>XP_006718625
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QNTSQQLRA 9
            + T+QQLRA
Sbjct: 1420 ERTAQQLRA 1428
>NP_057302
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QNTSQQLR 8
          Q TSQQLR
Sbjct: 73 QITSQQLR 80
>XP_005248593
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QNTSQQLR 8
          Q TSQQLR
Sbjct: 73 QITSQQLR 80
>XP_006714713
          Length = 884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QNTSQQLR 8
          Q TSQQLR
Sbjct: 73 QITSQQLR 80
>XP_005248591
          Length = 884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QNTSQQLR 8
          Q TSQQLR
Sbjct: 73 QITSQQLR 80
>XP_006726692
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NTSQQLRA 9
           +TSQ+LRA
Sbjct: 126 STSQKLRA 133
>XP_006721060
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NTSQQLRA 9
           +TSQ+LRA
Sbjct: 157 STSQKLRA 164
>XP_006710063
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NTSQQLRA 9
           +TSQ+LRA
Sbjct: 157 STSQKLRA 164
>NP_079197
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNTSQQLRA 9
           QNT Q+L +
Sbjct: 115 QNTEQELHS 123
>NP_057595
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSQQLRA 9
           NTSQ+L++
Sbjct: 95  NTSQELQS 102
>NP_066288
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSQQLR 8
           NT+QQL+
Sbjct: 465 NTAQQLK 471
>NP_055108
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QNTSQQLR 8
           Q+T++QLR
Sbjct: 127 QSTAEQLR 134
>XP_005262260
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNTSQQLRA 9
           QNT Q+L +
Sbjct: 115 QNTEQELHS 123
>XP_005262259
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNTSQQLRA 9
           QNT Q+L +
Sbjct: 115 QNTEQELHS 123
>XP_006723242
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NTSQQLRA 9
          NT QQL+A
Sbjct: 60 NTLQQLQA 67
>XP_005258889
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NTSQQLRA 9
          NT QQL+A
Sbjct: 60 NTLQQLQA 67
>XP_005253440
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  NTSQQLRA 9
          NTSQ+L++
Sbjct: 62 NTSQELQS 69
>NP_976219
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NTSQQLRA 9
          NT QQL+A
Sbjct: 60 NTLQQLQA 67
>NP_037500
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NTSQQLRA 9
          NT QQL+A
Sbjct: 60 NTLQQLQA 67
>NP_689759
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QNTSQQLR 8
           +NT QQL+
Sbjct: 390 ENTKQQLQ 397
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.104    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 405,922
Number of extensions: 579
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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