Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     390
NP_653080                                                              20     390
XP_005267292                                                           20     390
XP_005267291                                                           20     390
XP_005267290                                                           20     390
NP_001116151                                                           17    3301
XP_006714960                                                           17    3301
XP_005266007                                                           17    3301
NP_001185885                                                           16    5631
NP_001185886                                                           16    5631
NP_060912                                                              16    5631
NP_001017977                                                           16    5631
NP_060896                                                              16    5631
XP_006715232                                                           16    5631
XP_005249381                                                           16    5631
XP_005249380                                                           16    5631
XP_005249379                                                           16    5631
XP_005249377                                                           16    5631
XP_005249376                                                           16    5631
XP_005249375                                                           16    5631
XP_005249374                                                           16    5631
XP_005249373                                                           16    5631
XP_005249372                                                           16    5631
XP_005249371                                                           16    5631
XP_005249370                                                           16    5631
XP_005249369                                                           16    5631
XP_005249368                                                           16    5631
XP_005249367                                                           16    5631
XP_005249274                                                           16    5631
XP_005249273                                                           16    5631
XP_005249272                                                           16    5631
XP_005249271                                                           16    5631
XP_006715198                                                           16    5631
XP_005249269                                                           16    5631
XP_005249270                                                           16    5631
XP_005249268                                                           16    5631
XP_005245390                                                           16    5631
XP_005245389                                                           16    5631
XP_005245388                                                           16    5631
NP_775762                                                              16    5631
NP_055880                                                              16    7355
NP_064627                                                              16    7355
NP_001158238                                                           16    7355
NP_001026883                                                           16    7355
NP_003238                                                              16    7355
NP_008816                                                              16    7355
NP_060910                                                              16    7355
XP_005256014                                                           16    7355
XP_005271520                                                           16    7355
XP_005271519                                                           16    7355
XP_005271518                                                           16    7355
XP_006716525                                                           16    7355
XP_006716524                                                           16    7355
XP_006713328                                                           16    7355
XP_006713327                                                           16    7355
XP_006713326                                                           16    7355
XP_006713325                                                           16    7355
XP_006713324                                                           16    7355
XP_005265385                                                           16    7355
NP_001156863                                                           15    9605
NP_612152                                                              15    9605
NP_003239                                                              15    9605
XP_006715346                                                           15    9605
XP_006715345                                                           15    9605
>NP_005091
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QNSALTDTD 9
            QNSAL DTD
Sbjct: 1710 QNSALADTD 1718
>NP_653080
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QNSALTDTD 9
            QNSAL DTD
Sbjct: 1612 QNSALADTD 1620
>XP_005267292
          Length = 1677

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QNSALTDTD 9
            QNSAL DTD
Sbjct: 1605 QNSALADTD 1613
>XP_005267291
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QNSALTDTD 9
            QNSAL DTD
Sbjct: 1612 QNSALADTD 1620
>XP_005267290
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QNSALTDTD 9
            QNSAL DTD
Sbjct: 1710 QNSALADTD 1718
>NP_001116151
          Length = 2765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           +NSALT TD
Sbjct: 148 ENSALTLTD 156
>XP_006714960
          Length = 2758

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           +NSALT TD
Sbjct: 148 ENSALTLTD 156
>XP_005266007
          Length = 2765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           +NSALT TD
Sbjct: 148 ENSALTLTD 156
>NP_001185885
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 724 RDSALQDTD 732
>NP_001185886
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 693 RDSALQDTD 701
>NP_060912
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 667 RDSALQDTD 675
>NP_001017977
          Length = 860

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 647 RDSALQDTD 655
>NP_060896
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_006715232
          Length = 7498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2388 QNNTGTDTD 2396
>XP_005249381
          Length = 7281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2062 QNNTGTDTD 2070
>XP_005249380
          Length = 7607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2388 QNNTGTDTD 2396
>XP_005249379
          Length = 7633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2414 QNNTGTDTD 2422
>XP_005249377
          Length = 7640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2421 QNNTGTDTD 2429
>XP_005249376
          Length = 7647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2428 QNNTGTDTD 2436
>XP_005249375
          Length = 7680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2461 QNNTGTDTD 2469
>XP_005249374
          Length = 7709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2599 QNNTGTDTD 2607
>XP_005249373
          Length = 7723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2504 QNNTGTDTD 2512
>XP_005249372
          Length = 7785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2566 QNNTGTDTD 2574
>XP_005249371
          Length = 7788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2599 QNNTGTDTD 2607
>XP_005249370
          Length = 7794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2599 QNNTGTDTD 2607
>XP_005249369
          Length = 7797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2578 QNNTGTDTD 2586
>XP_005249368
          Length = 7812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2599 QNNTGTDTD 2607
>XP_005249367
          Length = 7818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QNSALTDTD 9
            QN+  TDTD
Sbjct: 2599 QNNTGTDTD 2607
>XP_005249274
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249273
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 794 ALTDTD 799
>XP_005249272
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 799 ALTDTD 804
>XP_005249271
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 808 ALTDTD 813
>XP_006715198
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249269
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249270
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 812 ALTDTD 817
>XP_005249268
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ALTDTD 9
           ALTDTD
Sbjct: 821 ALTDTD 826
>XP_005245390
          Length = 874

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 647 RDSALQDTD 655
>XP_005245389
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 667 RDSALQDTD 675
>XP_005245388
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QNSALTDTD 9
           ++SAL DTD
Sbjct: 724 RDSALQDTD 732
>NP_775762
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NSALTDTD 9
           N ALTD D
Sbjct: 195 NMALTDVD 202
>NP_055880
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSALTDT 8
           +SALTDT
Sbjct: 850 SSALTDT 856
>NP_064627
          Length = 1388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 689 QNSSILDND 697
>NP_001158238
          Length = 2789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NSALTDT 8
            N+A+TDT
Sbjct: 1925 NTAITDT 1931
>NP_001026883
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           Q+ ALT TD
Sbjct: 307 QDRALTQTD 315
>NP_003238
          Length = 1172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QNSALTDTD 9
           +N+A+++TD
Sbjct: 950 ENNAISETD 958
>NP_008816
          Length = 3703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NSALTDT 8
            N+A+TDT
Sbjct: 2839 NTAITDT 2845
>NP_060910
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QNSALTDTD 9
          QN ALT+ D
Sbjct: 83 QNGALTNGD 91
>XP_005256014
          Length = 3702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NSALTDT 8
            N+A+TDT
Sbjct: 2838 NTAITDT 2844
>XP_005271520
          Length = 1801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSALTDT 8
           +SALTDT
Sbjct: 662 SSALTDT 668
>XP_005271519
          Length = 1833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSALTDT 8
           +SALTDT
Sbjct: 694 SSALTDT 700
>XP_005271518
          Length = 1982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSALTDT 8
           +SALTDT
Sbjct: 843 SSALTDT 849
>XP_006716525
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QNSALTDTD 9
          QN ALT+ D
Sbjct: 83 QNGALTNGD 91
>XP_006716524
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QNSALTDTD 9
          QN ALT+ D
Sbjct: 83 QNGALTNGD 91
>XP_006713328
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 689 QNSSILDND 697
>XP_006713327
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 324 QNSSILDND 332
>XP_006713326
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 689 QNSSILDND 697
>XP_006713325
          Length = 1195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 689 QNSSILDND 697
>XP_006713324
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 689 QNSSILDND 697
>XP_005265385
          Length = 1291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           QNS++ D D
Sbjct: 592 QNSSILDND 600
>NP_001156863
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QNSALT 6
           QNSALT
Sbjct: 592 QNSALT 597
>NP_612152
          Length = 2849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QNSALTDTD 9
           +NS L D+D
Sbjct: 387 ENSCLEDSD 395
>NP_003239
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NSALTDTD 9
           NSA  DTD
Sbjct: 648 NSAQLDTD 655
>XP_006715346
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QNSALT 6
           QNSALT
Sbjct: 592 QNSALT 597
>XP_006715345
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QNSALT 6
           QNSALT
Sbjct: 592 QNSALT 597
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.107    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 492,402
Number of extensions: 1069
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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