Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              18    1135
NP_001186623                                                           17    2528
NP_001186622                                                           17    2528
NP_001186621                                                           17    2528
NP_003031                                                              17    2528
NP_001278253                                                           17    4312
NP_001275997                                                           17    4312
NP_060533                                                              17    4312
NP_001276001                                                           17    4312
NP_001275999                                                           17    4312
NP_001275998                                                           17    4312
NP_001275996                                                           17    4312
XP_006722053                                                           17    4312
XP_006722052                                                           17    4312
XP_006717874                                                           17    4312
NP_036558                                                              16    5631
NP_001193900                                                           16    5631
NP_001244286                                                           16    5631
NP_002828                                                              16    5631
NP_001103224                                                           16    5631
NP_001193901                                                           16    5631
XP_006719593                                                           16    5631
XP_006719592                                                           16    5631
XP_006719591                                                           16    5631
NP_001186346                                                           16    7355
NP_001413                                                              16    7355
NP_055651                                                              16    7355
NP_653310                                                              16    7355
NP_938195                                                              16    7355
NP_001229288                                                           16    7355
XP_006725396                                                           16    7355
XP_006725395                                                           16    7355
XP_006725394                                                           16    7355
XP_006725393                                                           16    7355
XP_006722057                                                           16    7355
XP_006722056                                                           16    7355
XP_006722055                                                           16    7355
XP_006722054                                                           16    7355
XP_006718152                                                           16    7355
XP_006718151                                                           16    7355
XP_006718150                                                           16    7355
XP_006718149                                                           16    7355
XP_006718148                                                           16    7355
XP_006718147                                                           16    7355
XP_006712015                                                           16    7355
NP_057056                                                              15    9605
NP_000074                                                              15    9605
NP_001596                                                              15    9605
NP_056153                                                              15    9605
NP_001158075                                                           15    9605
NP_079031                                                              15    9605
NP_001013865                                                           15    9605
XP_006723795                                                           15    9605
XP_006723794                                                           15    9605
XP_006723793                                                           15    9605
XP_006723792                                                           15    9605
XP_006723791                                                           15    9605
XP_006723790                                                           15    9605
XP_006721216                                                           15    9605
XP_005254726                                                           15    9605
XP_006720752                                                           15    9605
XP_006720748                                                           15    9605
XP_005266469                                                           15    9605
>NP_055365
          Length = 1032

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           Q VEAAGLE
Sbjct: 650 QRVEAAGLE 658
>NP_001186623
          Length = 1227

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QMVEAAG 7
           QMVEAAG
Sbjct: 648 QMVEAAG 654
>NP_001186622
          Length = 1232

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QMVEAAG 7
           QMVEAAG
Sbjct: 653 QMVEAAG 659
>NP_001186621
          Length = 1241

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QMVEAAG 7
           QMVEAAG
Sbjct: 662 QMVEAAG 668
>NP_003031
          Length = 1241

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QMVEAAG 7
           QMVEAAG
Sbjct: 662 QMVEAAG 668
>NP_001278253
          Length = 2639

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    MVEAAGLE 9
            +VEAAGL+
Sbjct: 1379 LVEAAGLD 1386
>NP_001275997
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 19 EQLEAAGLE 27
>NP_060533
          Length = 838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>NP_001276001
          Length = 708

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>NP_001275999
          Length = 740

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>NP_001275998
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>NP_001275996
          Length = 884

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>XP_006722053
          Length = 2608

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    MVEAAGLE 9
            +VEAAGL+
Sbjct: 1348 LVEAAGLD 1355
>XP_006722052
          Length = 2631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    MVEAAGLE 9
            +VEAAGL+
Sbjct: 1379 LVEAAGLD 1386
>XP_006717874
          Length = 813

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          + +EAAGLE
Sbjct: 35 EQLEAAGLE 43
>NP_036558
          Length = 1217

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QMVEAAG 7
           +MVEAAG
Sbjct: 822 EMVEAAG 828
>NP_001193900
          Length = 1907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 271 MTEAAGLQ 278
>NP_001244286
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QMVEAAGLE 9
           Q VEA GLE
Sbjct: 696 QSVEAHGLE 704
>NP_002828
          Length = 1997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 271 MTEAAGLQ 278
>NP_001103224
          Length = 2215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 489 MTEAAGLQ 496
>NP_001193901
          Length = 1907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 271 MTEAAGLQ 278
>XP_006719593
          Length = 1304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 489 MTEAAGLQ 496
>XP_006719592
          Length = 2012

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 271 MTEAAGLQ 278
>XP_006719591
          Length = 2230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           M EAAGL+
Sbjct: 489 MTEAAGLQ 496
>NP_001186346
          Length = 1491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 928 RIVEARGLE 936
>NP_001413
          Length = 255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMVEAAGL 8
           + VEAAGL
Sbjct: 96  EFVEAAGL 103
>NP_055651
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>NP_653310
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMVEAAGLE 9
           Q VEA+G E
Sbjct: 130 QKVEASGFE 138
>NP_938195
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMVEAAGL 8
           + VEAAGL
Sbjct: 106 EFVEAAGL 113
>NP_001229288
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006725396
          Length = 1144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 928 RIVEARGLE 936
>XP_006725395
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 928 RIVEARGLE 936
>XP_006725394
          Length = 1408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 845 RIVEARGLE 853
>XP_006725393
          Length = 1473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 910 RIVEARGLE 918
>XP_006722057
          Length = 1144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 928 RIVEARGLE 936
>XP_006722056
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 928 RIVEARGLE 936
>XP_006722055
          Length = 1408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 845 RIVEARGLE 853
>XP_006722054
          Length = 1473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VEA GLE
Sbjct: 910 RIVEARGLE 918
>XP_006718152
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006718151
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006718150
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006718149
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006718148
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006718147
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MVEAAGLE 9
           +VEA GLE
Sbjct: 353 LVEALGLE 360
>XP_006712015
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMVEAAGLE 9
           Q VEA+G E
Sbjct: 130 QKVEASGFE 138
>NP_057056
          Length = 133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          +MV+AAG +
Sbjct: 28 EMVQAAGTD 36
>NP_000074
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           ++VE+ GLE
Sbjct: 955 ELVESPGLE 963
>NP_001596
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EAAGLE 9
           EAAGLE
Sbjct: 142 EAAGLE 147
>NP_056153
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 36 QVIEAEGLK 44
>NP_001158075
          Length = 85

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 36 QVIEAEGLK 44
>NP_079031
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           +++EA G+E
Sbjct: 153 ELIEAEGIE 161
>NP_001013865
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           +++EA G+E
Sbjct: 153 ELIEAEGIE 161
>XP_006723795
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 26 QVIEAEGLK 34
>XP_006723794
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 36 QVIEAEGLK 44
>XP_006723793
          Length = 1513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 8  QVIEAEGLK 16
>XP_006723792
          Length = 1513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 8  QVIEAEGLK 16
>XP_006723791
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 26 QVIEAEGLK 34
>XP_006723790
          Length = 1540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          Q++EA GL+
Sbjct: 36 QVIEAEGLK 44
>XP_006721216
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EAAGLE 9
           EAAGLE
Sbjct: 142 EAAGLE 147
>XP_005254726
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           +++EA G+E
Sbjct: 288 ELIEAEGIE 296
>XP_006720752
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           +++EA G+E
Sbjct: 100 ELIEAEGIE 108
>XP_006720748
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QMVEAAGLE 9
           +++EA G+E
Sbjct: 288 ELIEAEGIE 296
>XP_005266469
          Length = 133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QMVEAAGLE 9
          +MV+AAG +
Sbjct: 28 EMVQAAGTD 36
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.122    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 316,259
Number of extensions: 502
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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