Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              22     103
NP_001029031                                                           17    2528
NP_001257377                                                           17    2528
NP_000009                                                              17    2528
NP_002778                                                              17    2528
NP_001257376                                                           17    2528
XP_006721579                                                           17    2528
NP_005195                                                              17    3301
NP_001231063                                                           17    3301
XP_006717440                                                           17    3301
XP_005252421                                                           17    3301
XP_005252423                                                           17    3301
NP_620689                                                              16    5631
NP_001618                                                              16    7355
NP_997196                                                              16    7355
NP_079483                                                              16    7355
NP_085130                                                              16    7355
NP_443161                                                              16    7355
NP_002301                                                              16    7355
NP_001121143                                                           16    7355
NP_004527                                                              16    7355
NP_001230212                                                           16    7355
NP_001230210                                                           16    7355
NP_001230209                                                           16    7355
NP_075043                                                              16    7355
NP_076994                                                              16    7355
XP_006725522                                                           16    7355
XP_006725520                                                           16    7355
XP_006725519                                                           16    7355
XP_006725518                                                           16    7355
XP_006725517                                                           16    7355
XP_006725516                                                           16    7355
XP_005276859                                                           16    7355
XP_005276857                                                           16    7355
XP_006726285                                                           16    7355
XP_006726284                                                           16    7355
XP_006726283                                                           16    7355
XP_006726282                                                           16    7355
XP_006721755                                                           16    7355
XP_005254133                                                           16    7355
XP_005254131                                                           16    7355
XP_005266053                                                           16    7355
XP_005266052                                                           16    7355
XP_005266051                                                           16    7355
XP_005248581                                                           16    7355
XP_005248580                                                           16    7355
XP_006714692                                                           16    7355
XP_006714691                                                           16    7355
XP_006714690                                                           16    7355
XP_006714689                                                           16    7355
XP_006710380                                                           16    7355
XP_005245788                                                           16    7355
XP_006710379                                                           16    7355
XP_006710378                                                           16    7355
NP_543146                                                              16    7355
NP_001609                                                              15    9605
NP_001243390                                                           15    9605
NP_001231800                                                           15    9605
NP_001334                                                              15    9605
NP_001037                                                              15    9605
NP_078880                                                              15    9605
NP_001139547                                                           15    9605
NP_077013                                                              15    9605
NP_001188408                                                           15    9605
NP_001188401                                                           15    9605
NP_001139548                                                           15    9605
NP_001188402                                                           15    9605
NP_078811                                                              15    9605
NP_006505                                                              15    9605
NP_001257820                                                           15    9605
XP_005265428                                                           15    9605
>NP_115803
          Length = 1156

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QMTQDNIFP 9
           QMTQ+NIFP
Sbjct: 282 QMTQENIFP 290
>NP_001029031
          Length = 633

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMTQDNIFP 9
          Q+T D +FP
Sbjct: 59 QLTTDQVFP 67
>NP_001257377
          Length = 579

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMTQDNIFP 9
          Q+T D +FP
Sbjct: 5  QLTTDQVFP 13
>NP_000009
          Length = 655

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMTQDNIFP 9
          Q+T D +FP
Sbjct: 81 QLTTDQVFP 89
>NP_002778
          Length = 234

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           QMT+DNI
Sbjct: 202 QMTEDNI 208
>NP_001257376
          Length = 678

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           Q+T D +FP
Sbjct: 104 QLTTDQVFP 112
>XP_006721579
          Length = 708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           Q+T D +FP
Sbjct: 127 QLTTDQVFP 135
>NP_005195
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           QMT+D  FP
Sbjct: 276 QMTEDVYFP 284
>NP_001231063
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           QMT+D  FP
Sbjct: 276 QMTEDVYFP 284
>XP_006717440
          Length = 397

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           QMT+D  FP
Sbjct: 276 QMTEDVYFP 284
>XP_005252421
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           QMT+D  FP
Sbjct: 276 QMTEDVYFP 284
>XP_005252423
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           QMT+D  FP
Sbjct: 276 QMTEDVYFP 284
>NP_620689
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMTQDNIFP 9
           Q+TQ NI P
Sbjct: 545 QLTQLNILP 553
>NP_001618
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   MTQDNIF 8
           +T+DN+F
Sbjct: 116 VTEDNVF 122
>NP_997196
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   MTQDNIFP 9
           +TQD  FP
Sbjct: 673 VTQDRAFP 680
>NP_079483
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TQDNIFP 9
          TQD +FP
Sbjct: 53 TQDPLFP 59
>NP_085130
          Length = 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   DNIFP 9
           DNIFP
Sbjct: 369 DNIFP 373
>NP_443161
          Length = 1412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           Q+T+DNI
Sbjct: 526 QVTEDNI 532
>NP_002301
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TQDNIF 8
           T+DNIF
Sbjct: 318 TEDNIF 323
>NP_001121143
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TQDNIF 8
           T+DNIF
Sbjct: 318 TEDNIF 323
>NP_004527
          Length = 1403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>NP_001230212
          Length = 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   MTQDNIF 8
           +T+DN+F
Sbjct: 116 VTEDNVF 122
>NP_001230210
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   MTQDNIF 8
           +T+DN+F
Sbjct: 116 VTEDNVF 122
>NP_001230209
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   MTQDNIF 8
           +T+DN+F
Sbjct: 116 VTEDNVF 122
>NP_075043
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 928 SQDQIFP 934
>NP_076994
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           T+D++FP
Sbjct: 484 TEDDLFP 490
>XP_006725522
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 452 SQDQIFP 458
>XP_006725520
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 702 SQDQIFP 708
>XP_006725519
          Length = 1139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 826 SQDQIFP 832
>XP_006725518
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 906 SQDQIFP 912
>XP_006725517
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_006725516
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_005276859
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 452 SQDQIFP 458
>XP_005276857
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 702 SQDQIFP 708
>XP_006726285
          Length = 1139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 826 SQDQIFP 832
>XP_006726284
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 906 SQDQIFP 912
>XP_006726283
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_006726282
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_006721755
          Length = 978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   MTQDNIFP 9
           +TQD  FP
Sbjct: 667 VTQDRAFP 674
>XP_005254133
          Length = 283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           T+D++FP
Sbjct: 265 TEDDLFP 271
>XP_005254131
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           T+D++FP
Sbjct: 458 TEDDLFP 464
>XP_005266053
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   DNIFP 9
           DNIFP
Sbjct: 369 DNIFP 373
>XP_005266052
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   DNIFP 9
           DNIFP
Sbjct: 369 DNIFP 373
>XP_005266051
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   DNIFP 9
           DNIFP
Sbjct: 369 DNIFP 373
>XP_005248581
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 452 SQDQIFP 458
>XP_005248580
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 702 SQDQIFP 708
>XP_006714692
          Length = 1139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 826 SQDQIFP 832
>XP_006714691
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TQDNIFP 9
           +QD IFP
Sbjct: 906 SQDQIFP 912
>XP_006714690
          Length = 1348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_006714689
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TQDNIFP 9
            +QD IFP
Sbjct: 1090 SQDQIFP 1096
>XP_006710380
          Length = 1398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           Q+T+DNI
Sbjct: 526 QVTEDNI 532
>XP_005245788
          Length = 1434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           Q+T+DNI
Sbjct: 526 QVTEDNI 532
>XP_006710379
          Length = 1452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           Q+T+DNI
Sbjct: 526 QVTEDNI 532
>XP_006710378
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QMTQDNI 7
           Q+T+DNI
Sbjct: 526 QVTEDNI 532
>NP_543146
          Length = 1393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TQDNIFP 9
          T D+IFP
Sbjct: 43 TSDHIFP 49
>NP_001609
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   QDNIFP 9
           QD IFP
Sbjct: 353 QDRIFP 358
>NP_001243390
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   MTQDNIFP 9
           + +DNI+P
Sbjct: 629 LCKDNIYP 636
>NP_001231800
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   QDNIFP 9
           Q NIFP
Sbjct: 574 QSNIFP 579
>NP_001334
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   QDNIFP 9
           Q NIFP
Sbjct: 595 QSNIFP 600
>NP_001037
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   MTQDNIFP 9
           + +DNI+P
Sbjct: 629 LCKDNIYP 636
>NP_078880
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           +QD++FP
Sbjct: 481 SQDDLFP 487
>NP_001139547
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           +QD++FP
Sbjct: 447 SQDDLFP 453
>NP_077013
          Length = 173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   QDNIFP 9
           QDN FP
Sbjct: 110 QDNSFP 115
>NP_001188408
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   QDNIFP 9
           QD++FP
Sbjct: 824 QDDVFP 829
>NP_001188401
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   QDNIFP 9
           QD++FP
Sbjct: 806 QDDVFP 811
>NP_001139548
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQDNIFP 9
           +QD++FP
Sbjct: 322 SQDDLFP 328
>NP_001188402
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   QDNIFP 9
           QD++FP
Sbjct: 739 QDDVFP 744
>NP_078811
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   QDNIFP 9
           QD++FP
Sbjct: 824 QDDVFP 829
>NP_006505
          Length = 1956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   MTQDNIFP 9
           +T D +FP
Sbjct: 520 VTDDGVFP 527
>NP_001257820
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   QDNIFP 9
           QDN FP
Sbjct: 96  QDNSFP 101
>XP_005265428
          Length = 1959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   MTQDNIFP 9
           +T D +FP
Sbjct: 523 VTDDGVFP 530
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,914
Number of extensions: 882
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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