Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_937816                                                              17    3301
NP_067003                                                              17    3301
NP_001181939                                                           17    3301
NP_937817                                                              17    3301
NP_001231293                                                           17    4312
NP_001073948                                                           17    4312
NP_001171164                                                           17    4312
XP_005248625                                                           17    4312
XP_006714732                                                           17    4312
NP_892006                                                              16    5631
NP_149062                                                              16    5631
NP_059116                                                              16    5631
NP_036564                                                              16    5631
XP_005267816                                                           16    5631
XP_006715488                                                           16    5631
XP_006715487                                                           16    5631
XP_006715486                                                           16    5631
XP_006715485                                                           16    5631
XP_006715484                                                           16    5631
XP_006715483                                                           16    5631
XP_006715482                                                           16    5631
XP_006715481                                                           16    5631
XP_006715480                                                           16    5631
XP_006715479                                                           16    5631
XP_006715478                                                           16    5631
XP_006715477                                                           16    5631
XP_006715476                                                           16    5631
XP_006715475                                                           16    5631
XP_006715474                                                           16    5631
XP_006715473                                                           16    5631
XP_006715472                                                           16    5631
XP_006715471                                                           16    5631
XP_006715470                                                           16    5631
XP_006711735                                                           16    5631
XP_005245698                                                           16    5631
NP_001138887                                                           16    5631
NP_002365                                                              16    7355
NP_079235                                                              16    7355
NP_055872                                                              16    7355
NP_056508                                                              16    7355
XP_006719852                                                           16    7355
XP_005266357                                                           16    7355
XP_006719851                                                           16    7355
XP_006719850                                                           16    7355
XP_006719849                                                           16    7355
XP_006719848                                                           16    7355
XP_005266356                                                           16    7355
XP_006719847                                                           16    7355
XP_006719846                                                           16    7355
XP_006719845                                                           16    7355
XP_006719844                                                           16    7355
XP_006719843                                                           16    7355
XP_006719842                                                           16    7355
XP_006719671                                                           16    7355
XP_005246623                                                           16    7355
XP_005246622                                                           16    7355
XP_005246621                                                           16    7355
XP_005246620                                                           16    7355
XP_005246619                                                           16    7355
XP_005246618                                                           16    7355
XP_005246617                                                           16    7355
XP_005246616                                                           16    7355
XP_006712596                                                           16    7355
XP_005246615                                                           16    7355
XP_005246614                                                           16    7355
XP_006712595                                                           16    7355
XP_006712594                                                           16    7355
XP_006712593                                                           16    7355
XP_005246613                                                           16    7355
XP_005246612                                                           16    7355
XP_006712592                                                           16    7355
XP_005246611                                                           16    7355
NP_689673                                                              16    7355
NP_001184033                                                           15    9605
XP_006718903                                                           15    9605
XP_006718902                                                           15    9605
>NP_937816
          Length = 602

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSENISGT 9
           ++EN+SGT
Sbjct: 113 LTENVSGT 120
>NP_067003
          Length = 607

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSENISGT 9
           ++EN+SGT
Sbjct: 118 LTENVSGT 125
>NP_001181939
          Length = 556

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MSENISGT 9
          ++EN+SGT
Sbjct: 67 LTENVSGT 74
>NP_937817
          Length = 626

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSENISGT 9
           ++EN+SGT
Sbjct: 113 LTENVSGT 120
>NP_001231293
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           +SEN+ GT
Sbjct: 116 LSENVEGT 123
>NP_001073948
          Length = 1731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           +SEN+ GT
Sbjct: 429 LSENVEGT 436
>NP_001171164
          Length = 1705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           +SEN+ GT
Sbjct: 429 LSENVEGT 436
>XP_005248625
          Length = 1418

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           +SEN+ GT
Sbjct: 116 LSENVEGT 123
>XP_006714732
          Length = 1633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           +SEN+ GT
Sbjct: 331 LSENVEGT 338
>NP_892006
          Length = 8797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2219 QMAENIS 2225
>NP_149062
          Length = 8749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>NP_059116
          Length = 781

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SENISGT 9
           SENISG+
Sbjct: 596 SENISGS 602
>NP_036564
          Length = 1290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MSENISG 8
           +SEN+SG
Sbjct: 511 LSENVSG 517
>XP_005267816
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SENISGT 9
           SENISG+
Sbjct: 588 SENISGS 594
>XP_006715488
          Length = 8721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715487
          Length = 8744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715486
          Length = 8758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715485
          Length = 8793

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2173 QMAENIS 2179
>XP_006715484
          Length = 8794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715483
          Length = 8795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715482
          Length = 8797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2219 QMAENIS 2225
>XP_006715481
          Length = 8799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2179 QMAENIS 2185
>XP_006715480
          Length = 8799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715479
          Length = 8804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715478
          Length = 8809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715477
          Length = 8822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2202 QMAENIS 2208
>XP_006715476
          Length = 8823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715475
          Length = 8827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715474
          Length = 8829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2209 QMAENIS 2215
>XP_006715473
          Length = 8832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715472
          Length = 8839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2219 QMAENIS 2225
>XP_006715471
          Length = 8842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006715470
          Length = 8846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QMSENIS 7
            QM+ENIS
Sbjct: 2226 QMAENIS 2232
>XP_006711735
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MSENISG 8
           +SEN+SG
Sbjct: 512 LSENVSG 518
>XP_005245698
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MSENISG 8
           +SEN+SG
Sbjct: 512 LSENVSG 518
>NP_001138887
          Length = 1291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MSENISG 8
           +SEN+SG
Sbjct: 511 LSENVSG 517
>NP_002365
          Length = 1827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 884 QDSENLSG 891
>NP_079235
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  MSENISGT 9
          M+E +SGT
Sbjct: 20 MAETVSGT 27
>NP_055872
          Length = 4678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>NP_056508
          Length = 942

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSENISGT 9
           M EN++GT
Sbjct: 353 MLENVTGT 360
>XP_006719852
          Length = 4752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_005266357
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719851
          Length = 4689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719850
          Length = 4697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719849
          Length = 4703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719848
          Length = 4737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_005266356
          Length = 4755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719847
          Length = 4761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1611 QSEENISG 1618
>XP_006719846
          Length = 4763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719845
          Length = 4772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719844
          Length = 4789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719843
          Length = 4794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719842
          Length = 4797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QMSENISG 8
            Q  ENISG
Sbjct: 1647 QSEENISG 1654
>XP_006719671
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  MSENISGT 9
          M+E +SGT
Sbjct: 20 MAETVSGT 27
>XP_005246623
          Length = 1757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 726 QDSENLSG 733
>XP_005246622
          Length = 1757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 726 QDSENLSG 733
>XP_005246621
          Length = 1823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 880 QDSENLSG 887
>XP_005246620
          Length = 1827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 884 QDSENLSG 891
>XP_005246619
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 807 QDSENLSG 814
>XP_005246618
          Length = 1911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 880 QDSENLSG 887
>XP_005246617
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 883 QDSENLSG 890
>XP_005246616
          Length = 1915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 884 QDSENLSG 891
>XP_006712596
          Length = 1939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_005246615
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_005246614
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_006712595
          Length = 1996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 965 QDSENLSG 972
>XP_006712594
          Length = 1996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_006712593
          Length = 1996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_005246613
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_005246612
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_006712592
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>XP_005246611
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSENISG 8
           Q SEN+SG
Sbjct: 966 QDSENLSG 973
>NP_689673
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ENISGT 9
           EN+SGT
Sbjct: 135 ENVSGT 140
>NP_001184033
          Length = 3972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ENISGT 9
            EN+SGT
Sbjct: 1600 ENLSGT 1605
>XP_006718903
          Length = 2673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ENISGT 9
           EN+SGT
Sbjct: 301 ENLSGT 306
>XP_006718902
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ENISGT 9
           EN+SGT
Sbjct: 592 ENLSGT 597
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.108    0.258 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,569
Number of extensions: 840
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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