Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           20     509
NP_004561                                                              20     509
NP_001275703                                                           20     509
XP_005253450                                                           20     509
XP_006719151                                                           20     509
NP_000121                                                              15    9605
NP_573572                                                              15    9605
NP_001106962                                                           15    9605
NP_055365                                                              15    9605
NP_001188357                                                           15    9605
NP_056345                                                              15    9605
NP_077299                                                              15    9605
NP_003584                                                              15    9605
XP_006724686                                                           15    9605
XP_005262147                                                           15    9605
XP_005262146                                                           15    9605
XP_005262145                                                           15    9605
XP_005262144                                                           15    9605
XP_005260135                                                           15    9605
XP_006722948                                                           15    9605
XP_005258103                                                           15    9605
XP_006712471                                                           15    9605



>NP_001275701
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMSAINPAK 9
            QMSAI+PAK
Sbjct: 1219 QMSAISPAK 1227





>NP_004561
          Length = 1445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMSAINPAK 9
            QMSAI+PAK
Sbjct: 1178 QMSAISPAK 1186





>NP_001275703
          Length = 1264

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMSAINPAK 9
            QMSAI+PAK
Sbjct: 997  QMSAISPAK 1005





>XP_005253450
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMSAINPAK 9
            QMSAI+PAK
Sbjct: 1219 QMSAISPAK 1227





>XP_006719151
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMSAINPAK 9
            QMSAI+PAK
Sbjct: 1219 QMSAISPAK 1227





>NP_000121
          Length = 2224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    SAINPAK 9
            SA+NP K
Sbjct: 1732 SAVNPEK 1738





>NP_573572
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 369 QLSCMRPAK 377





>NP_001106962
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 778 QLSCMRPAK 786





>NP_055365
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AINPAK 9
          A+NPAK
Sbjct: 41 ALNPAK 46





>NP_001188357
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QMSAINP 7
           Q+S++NP
Sbjct: 167 QLSSVNP 173





>NP_056345
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QMSAINP 7
           Q+S++NP
Sbjct: 235 QLSSVNP 241





>NP_077299
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSAINPA 8
           Q SAI+PA
Sbjct: 362 QASAISPA 369





>NP_003584
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AINPAK 9
           A+NPAK
Sbjct: 347 ALNPAK 352





>XP_006724686
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 369 QLSCMRPAK 377





>XP_005262147
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 369 QLSCMRPAK 377





>XP_005262146
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 778 QLSCMRPAK 786





>XP_005262145
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 778 QLSCMRPAK 786





>XP_005262144
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMSAINPAK 9
           Q+S + PAK
Sbjct: 778 QLSCMRPAK 786





>XP_005260135
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSAINPA 8
           Q SAI+PA
Sbjct: 244 QASAISPA 251





>XP_006722948
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMSAINPA 8
           Q SAI+PA
Sbjct: 362 QASAISPA 369





>XP_005258103
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AINPAK 9
           A+NPAK
Sbjct: 347 ALNPAK 352





>XP_006712471
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   QMSAINP 7
           Q+S++NP
Sbjct: 167 QLSSVNP 173





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.112    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 605,402
Number of extensions: 472
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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