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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           20     509
NP_004561                                                              20     509
NP_001275703                                                           20     509
XP_005253450                                                           20     509
XP_006719151                                                           20     509
NP_060264                                                              18    1935
XP_005251551                                                           18    1935
XP_006716857                                                           18    1935
NP_060959                                                              17    2528
XP_006711515                                                           17    2528
XP_006711514                                                           17    2528
XP_006711513                                                           17    2528
NP_477352                                                              17    4312
XP_005261692                                                           17    4312
XP_005261691                                                           17    4312
NP_001191006                                                           16    5631
NP_004779                                                              16    5631
NP_060392                                                              16    5631
NP_002901                                                              16    7355
NP_001186704                                                           16    7355
NP_001295                                                              16    7355
NP_001004488                                                           16    7355
NP_060546                                                              15    9605
NP_001276949                                                           15    9605
NP_001276950                                                           15    9605
NP_004216                                                              15    9605
NP_068773                                                              15    9605
NP_001274324                                                           15    9605
NP_002051                                                              15    9605
XP_005266410                                                           15    9605
XP_005252542                                                           15    9605
XP_006717518                                                           15    9605
XP_006717517                                                           15    9605
XP_006717516                                                           15    9605
XP_006712547                                                           15    9605
XP_005270807                                                           15    9605
NP_115991                                                              15    9605

>NP_001275701
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMLLNLLEM 9
            Q+LLNLLEM
Sbjct: 1152 QLLLNLLEM 1160



>NP_004561
          Length = 1445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMLLNLLEM 9
            Q+LLNLLEM
Sbjct: 1111 QLLLNLLEM 1119



>NP_001275703
          Length = 1264

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QMLLNLLEM 9
           Q+LLNLLEM
Sbjct: 930 QLLLNLLEM 938



>XP_005253450
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMLLNLLEM 9
            Q+LLNLLEM
Sbjct: 1152 QLLLNLLEM 1160



>XP_006719151
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QMLLNLLEM 9
            Q+LLNLLEM
Sbjct: 1152 QLLLNLLEM 1160



>NP_060264
          Length = 1801

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           Q+ LNLLEM
Sbjct: 379 QLALNLLEM 387



>XP_005251551
          Length = 1801

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           Q+ LNLLEM
Sbjct: 379 QLALNLLEM 387



>XP_006716857
          Length = 1834

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           Q+ LNLLEM
Sbjct: 412 QLALNLLEM 420



>NP_060959
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    QMLLNLLE 8
            Q+LLNLLE
Sbjct: 2921 QILLNLLE 2928



>XP_006711515
          Length = 2904

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    QMLLNLLE 8
            Q+LLNLLE
Sbjct: 2861 QILLNLLE 2868



>XP_006711514
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    QMLLNLLE 8
            Q+LLNLLE
Sbjct: 2921 QILLNLLE 2928



>XP_006711513
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    QMLLNLLE 8
            Q+LLNLLE
Sbjct: 2921 QILLNLLE 2928



>NP_477352
          Length = 2102

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QMLLNLLEM 9
           ++L+NLLE+
Sbjct: 728 ELLMNLLEL 736



>XP_005261692
          Length = 1854

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QMLLNLLEM 9
           ++L+NLLE+
Sbjct: 756 ELLMNLLEL 764



>XP_005261691
          Length = 2099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QMLLNLLEM 9
           ++L+NLLE+
Sbjct: 756 ELLMNLLEL 764



>NP_001191006
          Length = 1066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           QML NLL++
Sbjct: 383 QMLKNLLQL 391



>NP_004779
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           QML NLL++
Sbjct: 390 QMLKNLLQL 398



>NP_060392
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QMLLNLLEM 9
           ++ LNLLEM
Sbjct: 528 KLYLNLLEM 536



>NP_002901
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   MLLNLLE 8
           MLLNL+E
Sbjct: 194 MLLNLVE 200



>NP_001186704
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++LLNL+E
Sbjct: 325 ELLLNLIE 332



>NP_001295
          Length = 1380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++LLNL+E
Sbjct: 572 ELLLNLIE 579



>NP_001004488
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QMLLNLL 7
          QML+NLL
Sbjct: 79 QMLVNLL 85



>NP_060546
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 497 EVLINLLE 504



>NP_001276949
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 497 EVLINLLE 504



>NP_001276950
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QMLLNLLE 8
          ++L+NLLE
Sbjct: 22 EVLINLLE 29



>NP_004216
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QMLLNLLE 8
           Q+LL LLE
Sbjct: 818 QLLLELLE 825



>NP_068773
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MLLNLLEM 9
           +LLN+LE+
Sbjct: 215 LLLNMLEI 222



>NP_001274324
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           Q+LLNL++
Sbjct: 796 QLLLNLVD 803



>NP_002051
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MLLNLLEM 9
           ++LNLLE+
Sbjct: 221 LVLNLLEL 228



>XP_005266410
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MLLNLLEM 9
           +LLN+LE+
Sbjct: 215 LLLNMLEI 222



>XP_005252542
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 189 EVLINLLE 196



>XP_006717518
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 189 EVLINLLE 196



>XP_006717517
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 380 EVLINLLE 387



>XP_006717516
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           ++L+NLLE
Sbjct: 465 EVLINLLE 472



>XP_006712547
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QMLLNLLE 8
           Q+LLNL++
Sbjct: 793 QLLLNLVD 800



>XP_005270807
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MLLNLLEM 9
           ++LNLLE+
Sbjct: 221 LVLNLLEL 228



>NP_115991
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MLLNLLEM 9
           +LLN+LE+
Sbjct: 223 LLLNILEI 230



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.144    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,831
Number of extensions: 745
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)