Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              22     134
XP_006713721                                                           22     134
NP_085135                                                              18    1135
XP_005258413                                                           18    1135
NP_057666                                                              17    2528
NP_219499                                                              17    3301
XP_005250692                                                           17    3301
XP_005250691                                                           17    3301
NP_694967                                                              17    4312
NP_060830                                                              17    4312
NP_001162154                                                           17    4312
XP_005274615                                                           17    4312
XP_005266893                                                           17    4312
NP_056163                                                              16    5631
NP_065879                                                              16    5631
NP_851320                                                              16    5631
NP_003096                                                              16    5631
XP_005263969                                                           16    5631
XP_005263968                                                           16    5631
XP_005263967                                                           16    5631
XP_005263966                                                           16    5631
NP_002539                                                              16    5631
NP_055845                                                              16    7355
NP_665798                                                              16    7355
NP_665799                                                              16    7355
NP_001164163                                                           16    7355
NP_665801                                                              16    7355
NP_055944                                                              16    7355
NP_995586                                                              16    7355
NP_001164164                                                           16    7355
NP_001277251                                                           16    7355
NP_005500                                                              16    7355
NP_001277250                                                           16    7355
NP_001170977                                                           16    7355
NP_001628                                                              16    7355
NP_001257608                                                           16    7355
NP_612366                                                              16    7355
XP_006724813                                                           16    7355
XP_006724812                                                           16    7355
XP_006724811                                                           16    7355
XP_005262457                                                           16    7355
XP_005271969                                                           16    7355
XP_005271967                                                           16    7355
XP_005271966                                                           16    7355
XP_005248148                                                           16    7355
XP_005248147                                                           16    7355
XP_005248146                                                           16    7355
XP_005248145                                                           16    7355
XP_005248144                                                           16    7355
XP_005248143                                                           16    7355
XP_005248142                                                           16    7355
XP_005248141                                                           16    7355
XP_005248140                                                           16    7355
XP_005248139                                                           16    7355
NP_001265045                                                           15    9605
NP_001137435                                                           15    9605
NP_076493                                                              15    9605
NP_000416                                                              15    9605
NP_001025006                                                           15    9605
NP_113631                                                              15    9605
NP_001161407                                                           15    9605
NP_001161406                                                           15    9605
NP_009124                                                              15    9605
NP_003449                                                              15    9605
XP_006715849                                                           15    9605
XP_006715848                                                           15    9605
XP_006714136                                                           15    9605
XP_006713443                                                           15    9605
>NP_006209
          Length = 1068

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QMHNKTVSQ 9
           +MHNKTVSQ
Sbjct: 674 EMHNKTVSQ 682
>XP_006713721
          Length = 1068

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QMHNKTVSQ 9
           +MHNKTVSQ
Sbjct: 674 EMHNKTVSQ 682
>NP_085135
          Length = 2248

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MHNKTVSQ 9
           +HNKT+SQ
Sbjct: 828 LHNKTLSQ 835
>XP_005258413
          Length = 2249

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MHNKTVSQ 9
           +HNKT+SQ
Sbjct: 829 LHNKTLSQ 836
>NP_057666
          Length = 581

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           HN+TVSQ
Sbjct: 438 HNETVSQ 444
>NP_219499
          Length = 1663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    MHNKTVSQ 9
            M NKT+SQ
Sbjct: 1484 MKNKTISQ 1491
>XP_005250692
          Length = 964

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MHNKTVSQ 9
           M NKT+SQ
Sbjct: 785 MKNKTISQ 792
>XP_005250691
          Length = 1645

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    MHNKTVSQ 9
            M NKT+SQ
Sbjct: 1466 MKNKTISQ 1473
>NP_694967
          Length = 684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q HNKT+ +
Sbjct: 222 QRHNKTLKE 230
>NP_060830
          Length = 528

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q HNKT+ +
Sbjct: 216 QRHNKTLKE 224
>NP_001162154
          Length = 396

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMHNKTVSQ 9
          Q HNKT+ +
Sbjct: 84 QRHNKTLKE 92
>XP_005274615
          Length = 440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q HNKT+ +
Sbjct: 216 QRHNKTLKE 224
>XP_005266893
          Length = 684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q HNKT+ +
Sbjct: 222 QRHNKTLKE 230
>NP_056163
          Length = 1883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MHNKTVS 8
           +HN+TVS
Sbjct: 945 VHNRTVS 951
>NP_065879
          Length = 868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           HNKT+S+
Sbjct: 364 HNKTLSK 370
>NP_851320
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   HNKTVSQ 9
           HN TVSQ
Sbjct: 109 HNLTVSQ 115
>NP_003096
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    MHNKTV 7
            +HNKTV
Sbjct: 1892 LHNKTV 1897
>XP_005263969
          Length = 1844

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MHNKTVS 8
           +HN+TVS
Sbjct: 906 VHNRTVS 912
>XP_005263968
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MHNKTVS 8
           +HN+TVS
Sbjct: 923 VHNRTVS 929
>XP_005263967
          Length = 1899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MHNKTVS 8
           +HN+TVS
Sbjct: 962 VHNRTVS 968
>XP_005263966
          Length = 1900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MHNKTVS 8
           +HN+TVS
Sbjct: 962 VHNRTVS 968
>NP_002539
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  QMHNKTVS 8
          Q HNK +S
Sbjct: 86 QSHNKAIS 93
>NP_055845
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 653 QMHNK 657
>NP_665798
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>NP_665799
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>NP_001164163
          Length = 839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q  NK+VSQ
Sbjct: 429 QQKNKSVSQ 437
>NP_665801
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>NP_055944
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>NP_995586
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q  NK+VSQ
Sbjct: 293 QQKNKSVSQ 301
>NP_001164164
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QMHNKTVSQ 9
           Q  NK+VSQ
Sbjct: 429 QQKNKSVSQ 437
>NP_001277251
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2662 QCHNKTAN 2669
>NP_005500
          Length = 3027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2835 QCHNKTAN 2842
>NP_001277250
          Length = 3048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2856 QCHNKTAN 2863
>NP_001170977
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  QMHNKTV 7
          Q+HN TV
Sbjct: 56 QVHNSTV 62
>NP_001628
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  QMHNKTV 7
          Q+HN TV
Sbjct: 56 QVHNSTV 62
>NP_001257608
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMHNKTVSQ 9
          Q H++TV Q
Sbjct: 45 QQHHRTVHQ 53
>NP_612366
          Length = 351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QMHNKTVSQ 9
          Q H++TV Q
Sbjct: 45 QQHHRTVHQ 53
>XP_006724813
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>XP_006724812
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>XP_006724811
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>XP_005262457
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QMHNKTVSQ 9
          Q+ NK+VSQ
Sbjct: 31 QLVNKSVSQ 39
>XP_005271969
          Length = 3020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2828 QCHNKTAN 2835
>XP_005271967
          Length = 3065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2873 QCHNKTAN 2880
>XP_005271966
          Length = 3086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QMHNKTVS 8
            Q HNKT +
Sbjct: 2894 QCHNKTAN 2901
>XP_005248148
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 668 QMHNK 672
>XP_005248147
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 668 QMHNK 672
>XP_005248146
          Length = 3073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 760 QMHNK 764
>XP_005248145
          Length = 3079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 719 QMHNK 723
>XP_005248144
          Length = 3099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 745 QMHNK 749
>XP_005248143
          Length = 3105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 745 QMHNK 749
>XP_005248142
          Length = 3114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 760 QMHNK 764
>XP_005248141
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 760 QMHNK 764
>XP_005248140
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 760 QMHNK 764
>XP_005248139
          Length = 3120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 1   QMHNK 5
           QMHNK
Sbjct: 760 QMHNK 764
>NP_001265045
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QMHNKTV 7
           Q HNKT+
Sbjct: 291 QNHNKTL 297
>NP_001137435
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QMHNKTV 7
           Q HNKT+
Sbjct: 286 QNHNKTL 292
>NP_076493
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QMHNKTV 7
           Q HNKT+
Sbjct: 291 QNHNKTL 297
>NP_000416
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QMHNKTV 7
           Q HNKT+
Sbjct: 291 QNHNKTL 297
>NP_001025006
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 303 HSKTISE 309
>NP_113631
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 282 HSKTISE 288
>NP_001161407
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 191 HSKTISE 197
>NP_001161406
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 224 HSKTISE 230
>NP_009124
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   HNKTV 7
           HNKTV
Sbjct: 266 HNKTV 270
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QMHNKTVSQ 9
           Q HNK  +Q
Sbjct: 192 QCHNKVCNQ 200
>XP_006715849
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 212 HSKTISE 218
>XP_006715848
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   HNKTVSQ 9
           H+KT+S+
Sbjct: 245 HSKTISE 251
>XP_006714136
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   HNKTV 7
           HNKTV
Sbjct: 289 HNKTV 293
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QMHNKTVSQ 9
           Q HNK  +Q
Sbjct: 236 QCHNKVCNQ 244
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.106    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 475,998
Number of extensions: 566
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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