Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_009057                                                              17    4312
NP_001177957                                                           16    5631
NP_036602                                                              16    5631
XP_006715974                                                           16    5631
NP_060656                                                              16    7355
XP_005245376                                                           16    7355
XP_005245374                                                           16    7355
NP_001275743                                                           15    9605
NP_076996                                                              15    9605
NP_115826                                                              15    9605
XP_006716699                                                           15    9605
XP_006716698                                                           15    9605
XP_006716697                                                           15    9605
XP_006716696                                                           15    9605
XP_006716695                                                           15    9605
XP_006716694                                                           15    9605
XP_006716693                                                           15    9605
XP_006716692                                                           15    9605
XP_006716691                                                           15    9605
XP_006716690                                                           15    9605
XP_006716689                                                           15    9605
XP_006714561                                                           15    9605
>NP_009057
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QLVSQLLTI 9
           ++VSQLLT+
Sbjct: 323 RIVSQLLTL 331
>NP_001177957
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QLVSQLL 7
           QLVSQLL
Sbjct: 768 QLVSQLL 774
>NP_036602
          Length = 923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QLVSQLL 7
           QLVSQLL
Sbjct: 832 QLVSQLL 838
>XP_006715974
          Length = 875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   QLVSQLL 7
           QLVSQLL
Sbjct: 784 QLVSQLL 790
>NP_060656
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVSQLLT 8
           L+SQLLT
Sbjct: 313 LISQLLT 319
>XP_005245376
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVSQLLT 8
           L+SQLLT
Sbjct: 178 LISQLLT 184
>XP_005245374
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVSQLLT 8
           L+SQLLT
Sbjct: 371 LISQLLT 377
>NP_001275743
          Length = 1632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1041 QLISLLLTM 1049
>NP_076996
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLVSQLLT 8
           +L+SQ+LT
Sbjct: 294 KLISQMLT 301
>NP_115826
          Length = 1641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006716699
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1041 QLISLLLTM 1049
>XP_006716698
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006716697
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006716696
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLVSQLLTI 9
           QL+S LLT+
Sbjct: 982 QLISLLLTM 990
>XP_006716695
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLVSQLLTI 9
           QL+S LLT+
Sbjct: 982 QLISLLLTM 990
>XP_006716694
          Length = 1632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1041 QLISLLLTM 1049
>XP_006716693
          Length = 1644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1041 QLISLLLTM 1049
>XP_006716692
          Length = 1644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1041 QLISLLLTM 1049
>XP_006716691
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006716690
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006716689
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QLVSQLLTI 9
            QL+S LLT+
Sbjct: 1050 QLISLLLTM 1058
>XP_006714561
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLVSQLLT 8
           +L+SQ+LT
Sbjct: 294 KLISQMLT 301
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.138    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 273,794
Number of extensions: 262
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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