Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001269356                                                           18    1135
NP_001269355                                                           18    1135
NP_002640                                                              18    1135
NP_001275701                                                           18    1135
NP_004561                                                              18    1135
NP_001275703                                                           18    1135
XP_005253450                                                           18    1135
XP_006719151                                                           18    1135
XP_006716090                                                           18    1135
XP_005250500                                                           18    1135
NP_056076                                                              15    9605
>NP_001269356
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 662 QLVQAVKFE 670
>NP_001269355
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 662 QLVQAVKFE 670
>NP_002640
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 662 QLVQAVKFE 670
>NP_001275701
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 800 QLVQAVKFE 808
>NP_004561
          Length = 1445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 759 QLVQAVKFE 767
>NP_001275703
          Length = 1264

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 578 QLVQAVKFE 586
>XP_005253450
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 800 QLVQAVKFE 808
>XP_006719151
          Length = 1486

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 800 QLVQAVKFE 808
>XP_006716090
          Length = 878

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 662 QLVQAVKFE 670
>XP_005250500
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLVQAVMFE 9
           QLVQAV FE
Sbjct: 662 QLVQAVKFE 670
>NP_056076
          Length = 1498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVQAVMFE 9
           LVQ +MF+
Sbjct: 444 LVQEIMFD 451
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.137    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 180,085
Number of extensions: 148
Number of successful extensions: 11
Number of sequences better than 10000.0: 11
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 11
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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