Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005276293                                                           18    1135
XP_005264833                                                           18    1135
XP_005276006                                                           18    1135
NP_056022                                                              17    2528
XP_005245850                                                           17    2528
XP_006710544                                                           17    2528
XP_005245849                                                           17    2528
NP_001243115                                                           17    4312
NP_001243117                                                           17    4312
XP_006724705                                                           17    4312
NP_997199                                                              17    4312
NP_694960                                                              16    5631
NP_001243114                                                           16    5631
NP_001122085                                                           16    5631
NP_003786                                                              16    5631
NP_055954                                                              16    5631
NP_001258760                                                           16    5631
NP_037478                                                              16    5631
NP_001243116                                                           16    5631
NP_005015                                                              16    5631
XP_006726449                                                           16    5631
XP_006724706                                                           16    5631
XP_006721791                                                           16    5631
XP_005267249                                                           16    5631
XP_006712222                                                           16    5631
XP_006710542                                                           16    5631
XP_006710541                                                           16    5631
NP_001026855                                                           16    7355
NP_005417                                                              16    7355
NP_056034                                                              16    7355
NP_001269242                                                           16    7355
NP_001013861                                                           16    7355
NP_001138771                                                           16    7355
NP_001138770                                                           16    7355
NP_001138769                                                           16    7355
XP_006721852                                                           16    7355
XP_006721851                                                           16    7355
XP_006721850                                                           16    7355
XP_006721849                                                           16    7355
XP_005273303                                                           16    7355
NP_001034585                                                           16    7355
NP_758860                                                              15    9605
NP_689898                                                              15    9605
NP_005838                                                              15    9605
NP_115811                                                              15    9605
NP_001192222                                                           15    9605
NP_001192223                                                           15    9605
NP_000712                                                              15    9605
NP_055893                                                              15    9605
NP_061819                                                              15    9605
NP_055833                                                              15    9605
NP_001186871                                                           15    9605
NP_004740                                                              15    9605
NP_001248763                                                           15    9605
XP_006715463                                                           15    9605
XP_006715462                                                           15    9605
XP_006715461                                                           15    9605
XP_006715460                                                           15    9605
XP_006715459                                                           15    9605
XP_006715458                                                           15    9605
XP_006715457                                                           15    9605
XP_006715456                                                           15    9605
XP_006714806                                                           15    9605
XP_006714805                                                           15    9605
XP_006714804                                                           15    9605
XP_005272206                                                           15    9605
XP_005272205                                                           15    9605
>XP_005276293
          Length = 695

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   NLPLFQL 9
           NLPLFQL
Sbjct: 314 NLPLFQL 320
>XP_005264833
          Length = 441

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   NLPLFQL 9
           NLPLFQL
Sbjct: 314 NLPLFQL 320
>XP_005276006
          Length = 695

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   NLPLFQL 9
           NLPLFQL
Sbjct: 314 NLPLFQL 320
>NP_056022
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           QLN PL+Q+
Sbjct: 154 QLNAPLWQI 162
>XP_005245850
          Length = 384

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           QLN PL+Q+
Sbjct: 229 QLNAPLWQI 237
>XP_006710544
          Length = 415

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           QLN PL+Q+
Sbjct: 229 QLNAPLWQI 237
>XP_005245849
          Length = 465

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           QLN PL+Q+
Sbjct: 229 QLNAPLWQI 237
>NP_001243115
          Length = 92

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QLNLPLFQL 9
          + NLP+F+L
Sbjct: 51 ETNLPIFKL 59
>NP_001243117
          Length = 158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QLNLPLFQL 9
          + NLP+F+L
Sbjct: 51 ETNLPIFKL 59
>XP_006724705
          Length = 117

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QLNLPLFQL 9
          + NLP+F+L
Sbjct: 10 ETNLPIFKL 18
>NP_997199
          Length = 146

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  LNLPLFQL 9
          L LPLFQL
Sbjct: 19 LCLPLFQL 26
>NP_694960
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QLNLPLFQ 8
           Q+N+PL Q
Sbjct: 693 QINIPLHQ 700
>NP_001243114
          Length = 162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NLPLFQL 9
          NLP+F+L
Sbjct: 57 NLPIFKL 63
>NP_001122085
          Length = 270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLNLPLFQL 9
           Q+NLPL  L
Sbjct: 160 QVNLPLLTL 168
>NP_003786
          Length = 162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NLPLFQL 9
          NLP+F+L
Sbjct: 56 NLPIFKL 62
>NP_055954
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLNLPLF 7
           +LNLP+F
Sbjct: 129 KLNLPMF 135
>NP_001258760
          Length = 270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLNLPLFQL 9
           Q+NLPL  L
Sbjct: 160 QVNLPLLTL 168
>NP_037478
          Length = 162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NLPLFQL 9
          NLP+F+L
Sbjct: 57 NLPIFKL 63
>NP_001243116
          Length = 96

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NLPLFQL 9
          NLP+F+L
Sbjct: 57 NLPIFKL 63
>NP_005015
          Length = 397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           QL+LP F+L
Sbjct: 288 QLHLPKFKL 296
>XP_006726449
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LPLFQL 9
           LPLFQL
Sbjct: 207 LPLFQL 212
>XP_006724706
          Length = 108

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3 NLPLFQL 9
         NLP+F+L
Sbjct: 3 NLPIFKL 9
>XP_006721791
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QLNLPLFQ 8
           Q+N+PL Q
Sbjct: 622 QINIPLHQ 629
>XP_005267249
          Length = 140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NLPLFQL 9
          NLP+F+L
Sbjct: 34 NLPIFKL 40
>XP_006712222
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LPLFQL 9
           LPLFQL
Sbjct: 207 LPLFQL 212
>XP_006710542
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLNLPLF 7
           +LNLP+F
Sbjct: 129 KLNLPMF 135
>XP_006710541
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLNLPLF 7
           +LNLP+F
Sbjct: 129 KLNLPMF 135
>NP_001026855
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QLNLPLF 7
           Q+NLP F
Sbjct: 514 QINLPYF 520
>NP_005417
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QLNLPLF 7
           Q+NLP F
Sbjct: 385 QINLPYF 391
>NP_056034
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 552 NLPVFQ 557
>NP_001269242
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 555 NLPVFQ 560
>NP_001013861
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 583 NLPVFQ 588
>NP_001138771
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 606 NLPVFQ 611
>NP_001138770
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 575 NLPVFQ 580
>NP_001138769
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 634 NLPVFQ 639
>XP_006721852
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 565 NLPVFQ 570
>XP_006721851
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 588 NLPVFQ 593
>XP_006721850
          Length = 697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 596 NLPVFQ 601
>XP_006721849
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLP+FQ
Sbjct: 619 NLPVFQ 624
>XP_005273303
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QLNLPLF 7
           Q+NLP F
Sbjct: 505 QINLPYF 511
>NP_001034585
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QLNLPLFQL 9
          QLN+PL ++
Sbjct: 40 QLNMPLSEV 48
>NP_758860
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           +LN+PL +L
Sbjct: 330 ELNMPLTRL 338
>NP_689898
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 102 IRLPLFQ 108
>NP_005838
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 102 IRLPLFQ 108
>NP_115811
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           +LN+ +FQL
Sbjct: 478 ELNILIFQL 486
>NP_001192222
          Length = 2313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QLNLPLFQ 8
            Q N P+FQ
Sbjct: 1893 QKNAPMFQ 1900
>NP_001192223
          Length = 2251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QLNLPLFQ 8
            Q N P+FQ
Sbjct: 1874 QKNAPMFQ 1881
>NP_000712
          Length = 2270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    QLNLPLFQ 8
            Q N P+FQ
Sbjct: 1893 QKNAPMFQ 1900
>NP_055893
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLPLFQ 8
           NLPLF+
Sbjct: 745 NLPLFK 750
>NP_061819
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QLNLPLFQL 9
           +LN+P F++
Sbjct: 124 ELNVPFFKV 132
>NP_055833
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2315 NLPQFQM 2321
>NP_001186871
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2306 NLPQFQM 2312
>NP_004740
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNLPLFQ 8
           L+LPLF+
Sbjct: 345 LSLPLFE 351
>NP_001248763
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNLPLFQ 8
           L+LPLF+
Sbjct: 356 LSLPLFE 362
>XP_006715463
          Length = 2434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2264 NLPQFQM 2270
>XP_006715462
          Length = 2452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2282 NLPQFQM 2288
>XP_006715461
          Length = 2456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2306 NLPQFQM 2312
>XP_006715460
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2315 NLPQFQM 2321
>XP_006715459
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2305 NLPQFQM 2311
>XP_006715458
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2306 NLPQFQM 2312
>XP_006715457
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2315 NLPQFQM 2321
>XP_006715456
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NLPLFQL 9
            NLP FQ+
Sbjct: 2315 NLPQFQM 2321
>XP_006714806
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 237 IRLPLFQ 243
>XP_006714805
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 237 IRLPLFQ 243
>XP_006714804
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 237 IRLPLFQ 243
>XP_005272206
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 237 IRLPLFQ 243
>XP_005272205
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LNLPLFQ 8
           + LPLFQ
Sbjct: 237 IRLPLFQ 243
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.153    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 614,451
Number of extensions: 766
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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