Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              17    2528
NP_066124                                                              17    2528
XP_006717999                                                           17    2528
NP_001010893                                                           17    4312
NP_056369                                                              16    5631
XP_005254355                                                           16    5631
NP_002411                                                              16    7355
NP_001238953                                                           16    7355
NP_001238949                                                           16    7355
NP_061819                                                              16    7355
NP_079247                                                              16    7355
NP_001007472                                                           16    7355
NP_066003                                                              16    7355
NP_996830                                                              16    7355
NP_996829                                                              16    7355
NP_996828                                                              16    7355
NP_996827                                                              16    7355
XP_005252275                                                           16    7355
NP_060764                                                              15    9605
NP_001161814                                                           15    9605
NP_001161811                                                           15    9605
NP_001239542                                                           15    9605
NP_689787                                                              15    9605
NP_001161813                                                           15    9605
NP_001161812                                                           15    9605
NP_001239541                                                           15    9605
NP_001014972                                                           15    9605
NP_055312                                                              15    9605
XP_006712053                                                           15    9605
XP_005264320                                                           15    9605
XP_006712052                                                           15    9605
XP_005264319                                                           15    9605
XP_005264318                                                           15    9605
NP_001092691                                                           15    9605
>NP_065681
          Length = 1072

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLLVTVEES 9
           QLLVTVE S
Sbjct: 499 QLLVTVEGS 507
>NP_066124
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLLVTVEES 9
           QLLVTVE S
Sbjct: 499 QLLVTVEGS 507
>XP_006717999
          Length = 1207

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLLVTVEES 9
           QLLVTVE S
Sbjct: 592 QLLVTVEGS 600
>NP_001010893
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LLVTVEES 9
          LLVT+EE+
Sbjct: 12 LLVTIEEA 19
>NP_056369
          Length = 617

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLLVTVEES 9
           QLL T++ES
Sbjct: 587 QLLSTIDES 595
>XP_005254355
          Length = 617

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLLVTVEES 9
           QLL T++ES
Sbjct: 587 QLLSTIDES 595
>NP_002411
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 309 QLLVTIQKT 317
>NP_001238953
          Length = 1625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 331 QLLVTIQKT 339
>NP_001238949
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 348 QLLVTIQKT 356
>NP_061819
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLVTVEE 8
           ++LVTVEE
Sbjct: 334 KVLVTVEE 341
>NP_079247
          Length = 1566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 239 QLLVTIQKT 247
>NP_001007472
          Length = 1707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 392 QLLVTIQKT 400
>NP_066003
          Length = 1554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 239 QLLVTIQKT 247
>NP_996830
          Length = 1569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 264 QLLVTIQKT 272
>NP_996829
          Length = 1579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 264 QLLVTIQKT 272
>NP_996828
          Length = 1556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 239 QLLVTIQKT 247
>NP_996827
          Length = 1544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 239 QLLVTIQKT 247
>XP_005252275
          Length = 1734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QLLVTVEES 9
           QLLVT++++
Sbjct: 419 QLLVTIQKT 427
>NP_060764
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLVTVEES 9
           Q+L  VEES
Sbjct: 278 QILAPVEES 286
>NP_001161814
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLVTVEES 9
           LLVTVE++
Sbjct: 395 LLVTVEKA 402
>NP_001161811
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLVTVEES 9
           LLVTVE++
Sbjct: 558 LLVTVEKA 565
>NP_001239542
          Length = 1957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1616 QALVTVDE 1623
>NP_689787
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLVTVEES 9
           LLVTVE++
Sbjct: 560 LLVTVEKA 567
>NP_001161813
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLVTVEES 9
           LLVTVE++
Sbjct: 491 LLVTVEKA 498
>NP_001161812
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLVTVEES 9
           LLVTVE++
Sbjct: 547 LLVTVEKA 554
>NP_001239541
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1616 QALVTVDE 1623
>NP_001014972
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1616 QALVTVDE 1623
>NP_055312
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1616 QALVTVDE 1623
>XP_006712053
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1105 QALVTVDE 1112
>XP_005264320
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1105 QALVTVDE 1112
>XP_006712052
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1105 QALVTVDE 1112
>XP_005264319
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1722 QALVTVDE 1729
>XP_005264318
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLVTVEE 8
            Q LVTV+E
Sbjct: 1722 QALVTVDE 1729
>NP_001092691
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLVTVEE 8
           Q+LV VEE
Sbjct: 111 QMLVRVEE 118
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.121    0.265 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 463,013
Number of extensions: 920
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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