Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     509
NP_848552                                                              18    1482
XP_005260332                                                           18    1482
XP_005260331                                                           18    1482
XP_005260330                                                           18    1482
XP_006723761                                                           18    1482
XP_005260329                                                           18    1482
NP_000095                                                              17    2528
NP_001013725                                                           17    2528
NP_653081                                                              17    2528
NP_055650                                                              17    2528
NP_060500                                                              17    2528
NP_001229437                                                           17    2528
NP_542164                                                              17    2528
NP_001265578                                                           17    2528
XP_006722445                                                           17    2528
XP_006722443                                                           17    2528
XP_005254450                                                           17    2528
XP_005254449                                                           17    2528
NP_001265853                                                           17    3301
NP_001258631                                                           17    3301
NP_002052                                                              16    5631
NP_001164638                                                           16    5631
NP_776173                                                              16    5631
XP_006719419                                                           16    5631
XP_006719417                                                           16    5631
XP_006719416                                                           16    5631
XP_006719415                                                           16    5631
XP_006719414                                                           16    5631
XP_006719413                                                           16    5631
XP_006719412                                                           16    5631
XP_006719411                                                           16    5631
XP_005270811                                                           16    5631
NP_055670                                                              16    7355
NP_001138424                                                           16    7355
NP_001177369                                                           15    9605
NP_006302                                                              15    9605
NP_207646                                                              15    9605
NP_001490                                                              15    9605
NP_001003722                                                           15    9605
NP_114147                                                              15    9605
NP_001139187                                                           15    9605
XP_006726591                                                           15    9605
XP_005260150                                                           15    9605
XP_005256932                                                           15    9605
XP_006721667                                                           15    9605
XP_005256931                                                           15    9605
XP_005256930                                                           15    9605
XP_006721666                                                           15    9605
XP_005256929                                                           15    9605
XP_005256928                                                           15    9605
XP_006721665                                                           15    9605
XP_005256925                                                           15    9605
XP_005256924                                                           15    9605
XP_006721664                                                           15    9605
XP_005256923                                                           15    9605
XP_005268191                                                           15    9605
XP_006718462                                                           15    9605
XP_006717124                                                           15    9605
XP_006717123                                                           15    9605
XP_005251982                                                           15    9605
XP_006717122                                                           15    9605
XP_006717121                                                           15    9605
XP_006716050                                                           15    9605
XP_006710008                                                           15    9605
NP_115881                                                              15    9605
>NP_004295
          Length = 1620

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           QLL HNEAA
Sbjct: 364 QLLPHNEAA 372
>NP_848552
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>XP_005260332
          Length = 1256

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>XP_005260331
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>XP_005260330
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>XP_006723761
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>XP_005260329
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLLSHNEA 8
           QL+SHN+A
Sbjct: 410 QLISHNQA 417
>NP_000095
          Length = 543

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QLLSHNE 7
           +LLSHNE
Sbjct: 223 ELLSHNE 229
>NP_001013725
          Length = 1649

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QLLSHNEAA 9
            Q+  HNEAA
Sbjct: 1094 QIYEHNEAA 1102
>NP_653081
          Length = 480

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 222 ELLKHNEA 229
>NP_055650
          Length = 468

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 210 ELLKHNEA 217
>NP_060500
          Length = 437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 182 ELLEHNEA 189
>NP_001229437
          Length = 568

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 313 ELLEHNEA 320
>NP_542164
          Length = 950

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 695 ELLEHNEA 702
>NP_001265578
          Length = 370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 130 ELLKHNEA 137
>XP_006722445
          Length = 905

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 650 ELLEHNEA 657
>XP_006722443
          Length = 925

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLLSHNEA 8
           +LL HNEA
Sbjct: 670 ELLEHNEA 677
>XP_005254450
          Length = 1505

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QLLSHNEAA 9
            Q+  HNEAA
Sbjct: 1094 QIYEHNEAA 1102
>XP_005254449
          Length = 1626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QLLSHNEAA 9
            Q+  HNEAA
Sbjct: 1094 QIYEHNEAA 1102
>NP_001265853
          Length = 276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QLLSHNEAA 9
          QLLSH  AA
Sbjct: 42 QLLSHQAAA 50
>NP_001258631
          Length = 365

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QLLSHNEAA 9
          QLLSH  AA
Sbjct: 42 QLLSHQAAA 50
>NP_002052
          Length = 274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLLSHNE 7
           QLL+HN+
Sbjct: 210 QLLTHND 216
>NP_001164638
          Length = 1241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLLSHNEA 8
            +LLSH EA
Sbjct: 1180 KLLSHQEA 1187
>NP_776173
          Length = 758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 529 QLLEHSELA 537
>XP_006719419
          Length = 443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 214 QLLEHSELA 222
>XP_006719417
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 529 QLLEHSELA 537
>XP_006719416
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 386 QLLEHSELA 394
>XP_006719415
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 386 QLLEHSELA 394
>XP_006719414
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 479 QLLEHSELA 487
>XP_006719413
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 529 QLLEHSELA 537
>XP_006719412
          Length = 724

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 529 QLLEHSELA 537
>XP_006719411
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           QLL H+E A
Sbjct: 509 QLLEHSELA 517
>XP_005270811
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLLSHNE 7
           QLL+HN+
Sbjct: 188 QLLTHND 194
>NP_055670
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSHNEAA 9
           LSH EAA
Sbjct: 375 LSHGEAA 381
>NP_001138424
          Length = 2172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLSHNEAA 9
           Q +SH EAA
Sbjct: 122 QSVSHGEAA 130
>NP_001177369
          Length = 2337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1082 LTSHNQAS 1089
>NP_006302
          Length = 2440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1066 LTSHNQAS 1073
>NP_207646
          Length = 2572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           Q+LSH+ +A
Sbjct: 186 QILSHDTSA 194
>NP_001490
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 491 EVASHHEAA 499
>NP_001003722
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 491 EVASHHEAA 499
>NP_114147
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LSHNEA 8
           LSHN+A
Sbjct: 231 LSHNQA 236
>NP_001139187
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QLLSHNE 7
           QLL HN+
Sbjct: 332 QLLQHNK 338
>XP_006726591
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QLLSHN 6
           +LLSHN
Sbjct: 158 ELLSHN 163
>XP_005260150
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LSHNEA 8
           LSHN+A
Sbjct: 231 LSHNQA 236
>XP_005256932
          Length = 2448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1150 LTSHNQAS 1157
>XP_006721667
          Length = 2456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1082 LTSHNQAS 1089
>XP_005256931
          Length = 2466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1092 LTSHNQAS 1099
>XP_005256930
          Length = 2508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1134 LTSHNQAS 1141
>XP_006721666
          Length = 2511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1150 LTSHNQAS 1157
>XP_005256929
          Length = 2514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1140 LTSHNQAS 1147
>XP_005256928
          Length = 2515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1141 LTSHNQAS 1148
>XP_006721665
          Length = 2523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1149 LTSHNQAS 1156
>XP_005256925
          Length = 2523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1149 LTSHNQAS 1156
>XP_005256924
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1150 LTSHNQAS 1157
>XP_006721664
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1150 LTSHNQAS 1157
>XP_005256923
          Length = 2524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LLSHNEAA 9
            L SHN+A+
Sbjct: 1150 LTSHNQAS 1157
>XP_005268191
          Length = 2572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           Q+LSH+ +A
Sbjct: 186 QILSHDTSA 194
>XP_006718462
          Length = 4966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QLLSHN 6
           +LLSHN
Sbjct: 222 ELLSHN 227
>XP_006717124
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 252 EVASHHEAA 260
>XP_006717123
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 494 EVASHHEAA 502
>XP_005251982
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 502 EVASHHEAA 510
>XP_006717122
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 503 EVASHHEAA 511
>XP_006717121
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLLSHNEAA 9
           ++ SH+EAA
Sbjct: 505 EVASHHEAA 513
>XP_006716050
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QLLSHNE 7
           QLL HN+
Sbjct: 332 QLLQHNK 338
>XP_006710008
          Length = 2014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QLLSHN 6
           +LLSHN
Sbjct: 222 ELLSHN 227
>NP_115881
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QLLSHNEAA 9
          +LLSH++ A
Sbjct: 61 RLLSHDQVA 69
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.113    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 537,389
Number of extensions: 620
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package