Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001095139                                                           16    7355
NP_003857                                                              16    7355
XP_005263382                                                           16    7355
XP_005263381                                                           16    7355
XP_006714466                                                           16    7355
XP_005263380                                                           16    7355
XP_006714465                                                           16    7355
XP_005263379                                                           16    7355
XP_006714464                                                           16    7355
XP_006714463                                                           16    7355
NP_114115                                                              16    7355
NP_001265491                                                           15    9605
NP_997221                                                              15    9605
XP_006720493                                                           15    9605
>NP_001095139
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 616 QCLMLTLRR 624
>NP_003857
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 616 QCLMLTLRR 624
>XP_005263382
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 431 QCLMLTLRR 439
>XP_005263381
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 440 QCLMLTLRR 448
>XP_006714466
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 440 QCLMLTLRR 448
>XP_005263380
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 487 QCLMLTLRR 495
>XP_006714465
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 616 QCLMLTLRR 624
>XP_005263379
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 625 QCLMLTLRR 633
>XP_006714464
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 616 QCLMLTLRR 624
>XP_006714463
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLLMLAIRR 9
           Q LML +RR
Sbjct: 625 QCLMLTLRR 633
>NP_114115
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLLMLAIRR 9
           Q +MLA+RR
Sbjct: 272 QSVMLALRR 280
>NP_001265491
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMLAIRR 9
           LLML +RR
Sbjct: 385 LLMLLLRR 392
>NP_997221
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMLAIRR 9
           LLML +RR
Sbjct: 558 LLMLLLRR 565
>XP_006720493
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMLAIRR 9
           LLML +RR
Sbjct: 558 LLMLLLRR 565
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.356    0.157    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 222,938
Number of extensions: 194
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)

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