Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              20     509
NP_001276866                                                           18    1482
NP_004439                                                              18    1482
NP_001276865                                                           18    1482
NP_001005862                                                           18    1482
XP_005257197                                                           18    1482
XP_006721828                                                           18    1482
NP_001036064                                                           17    3301
NP_005226                                                              17    3301
XP_005246434                                                           17    3301
XP_005246433                                                           17    3301
XP_005246432                                                           17    3301
XP_006712427                                                           17    3301
NP_112235                                                              17    4312
NP_001269346                                                           17    4312
NP_001035915                                                           17    4312
NP_689564                                                              17    4312
NP_001257577                                                           17    4312
XP_005259057                                                           17    4312
XP_005259056                                                           17    4312
XP_006723307                                                           17    4312
XP_005259055                                                           17    4312
XP_006721514                                                           17    4312
XP_006721513                                                           17    4312
XP_005256514                                                           17    4312
NP_059128                                                              17    4312
NP_001192209                                                           16    5631
NP_002449                                                              16    7355
NP_060124                                                              16    7355
NP_001180236                                                           16    7355
NP_055928                                                              15    9605
NP_000664                                                              15    9605
NP_077808                                                              15    9605
NP_001159976                                                           15    9605
NP_001128653                                                           15    9605
NP_001011547                                                           15    9605
NP_006573                                                              15    9605
NP_940933                                                              15    9605
XP_006722513                                                           15    9605
XP_006722512                                                           15    9605
XP_005266752                                                           15    9605
XP_005266751                                                           15    9605
XP_006722511                                                           15    9605
XP_006722510                                                           15    9605
XP_005266750                                                           15    9605
XP_005266749                                                           15    9605
XP_005266748                                                           15    9605
XP_005266747                                                           15    9605
XP_005256619                                                           15    9605
XP_006721549                                                           15    9605
XP_006721548                                                           15    9605
XP_005256618                                                           15    9605
XP_005256617                                                           15    9605
XP_006718527                                                           15    9605
>NP_005219
          Length = 1210

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QLI QLMPF
Sbjct: 787 QLITQLMPF 795
>NP_001276866
          Length = 1055

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 795 QLVTQLMPY 803
>NP_004439
          Length = 1255

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 795 QLVTQLMPY 803
>NP_001276865
          Length = 1240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 780 QLVTQLMPY 788
>NP_001005862
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 765 QLVTQLMPY 773
>XP_005257197
          Length = 1225

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 765 QLVTQLMPY 773
>XP_006721828
          Length = 1336

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLIMQLMPF 9
           QL+ QLMP+
Sbjct: 876 QLVTQLMPY 884
>NP_001036064
          Length = 1292

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 793 QLVTQLMP 800
>NP_005226
          Length = 1308

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 793 QLVTQLMP 800
>XP_005246434
          Length = 1282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 783 QLVTQLMP 790
>XP_005246433
          Length = 1298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 783 QLVTQLMP 790
>XP_005246432
          Length = 1307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 808 QLVTQLMP 815
>XP_006712427
          Length = 1323

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL+ QLMP
Sbjct: 808 QLVTQLMP 815
>NP_112235
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 447 KLIMQLIP 454
>NP_001269346
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 288 KLVMELMP 295
>NP_001035915
          Length = 596

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 355 KLVMELMP 362
>NP_689564
          Length = 612

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 371 KLVMELMP 378
>NP_001257577
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 328 KLVMELMP 335
>XP_005259057
          Length = 416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 139 KLIMQLIP 146
>XP_005259056
          Length = 416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 139 KLIMQLIP 146
>XP_006723307
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 154 KLIMQLIP 161
>XP_005259055
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 154 KLIMQLIP 161
>XP_006721514
          Length = 596

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 355 KLVMELMP 362
>XP_006721513
          Length = 598

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 320 KLVMELMP 327
>XP_005256514
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +L+M+LMP
Sbjct: 355 KLVMELMP 362
>NP_059128
          Length = 416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           +LIMQL+P
Sbjct: 139 KLIMQLIP 146
>NP_001192209
          Length = 192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LIMQLMP 8
          L++QLMP
Sbjct: 41 LVLQLMP 47
>NP_002449
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           QL++QL+P
Sbjct: 535 QLLVQLVP 542
>NP_060124
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IMQLMPF 9
            I+QL+PF
Sbjct: 1210 ILQLIPF 1216
>NP_001180236
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IMQLMPF 9
            I+QL+PF
Sbjct: 1210 ILQLIPF 1216
>NP_055928
          Length = 2961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QLIMQLMP 8
            QLI++L+P
Sbjct: 2142 QLIIRLLP 2149
>NP_000664
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLIMQLMPF 9
           QLI  ++PF
Sbjct: 356 QLITHVLPF 364
>NP_077808
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QLIMQLMP 8
          Q+I+QL P
Sbjct: 32 QVILQLQP 39
>NP_001159976
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLIMQLMPF 9
           QLI  ++PF
Sbjct: 364 QLITHVLPF 372
>NP_001128653
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           +L+M LMP
Sbjct: 397 KLVMALMP 404
>NP_001011547
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           +L+M LMP
Sbjct: 372 KLVMALMP 379
>NP_006573
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QLIMQLMP 8
          Q+I+QL P
Sbjct: 32 QVILQLQP 39
>NP_940933
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722513
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 267 ILQLFPF 273
>XP_006722512
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 321 ILQLFPF 327
>XP_005266752
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266751
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722511
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_006722510
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266750
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266749
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266748
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005266747
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMQLMPF 9
           I+QL PF
Sbjct: 627 ILQLFPF 633
>XP_005256619
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           QLI++L+P
Sbjct: 758 QLIIRLLP 765
>XP_006721549
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLIMQLMP 8
           QLI++L+P
Sbjct: 758 QLIIRLLP 765
>XP_006721548
          Length = 1886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QLIMQLMP 8
            QLI++L+P
Sbjct: 1063 QLIIRLLP 1070
>XP_005256618
          Length = 2962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QLIMQLMP 8
            QLI++L+P
Sbjct: 2143 QLIIRLLP 2150
>XP_005256617
          Length = 2966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QLIMQLMP 8
            QLI++L+P
Sbjct: 2143 QLIIRLLP 2150
>XP_006718527
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QLIMQLMP 8
           QL++QL P
Sbjct: 235 QLLLQLRP 242
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.153    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 385,081
Number of extensions: 642
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package