Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              20     299
NP_056377                                                              18    1935
NP_000278                                                              17    2528
NP_005087                                                              17    2528
NP_001164634                                                           17    2528
NP_001164633                                                           17    2528
NP_963893                                                              17    2528
XP_005262367                                                           17    2528
XP_006724778                                                           17    2528
XP_005262366                                                           17    2528
XP_005249237                                                           17    2528
NP_001123230                                                           17    4312
NP_071752                                                              17    4312
NP_000042                                                              16    5631
NP_004841                                                              16    5631
XP_006718907                                                           16    5631
XP_006718906                                                           16    5631
XP_005271619                                                           16    5631
XP_005271618                                                           16    5631
XP_005246247                                                           16    5631
NP_005643                                                              16    7355
NP_001073953                                                           16    7355
NP_055872                                                              16    7355
NP_060105                                                              16    7355
XP_005256181                                                           16    7355
XP_005256180                                                           16    7355
XP_005256179                                                           16    7355
XP_005256178                                                           16    7355
XP_006719852                                                           16    7355
XP_005266357                                                           16    7355
XP_006719851                                                           16    7355
XP_006719850                                                           16    7355
XP_006719849                                                           16    7355
XP_006719848                                                           16    7355
XP_005266356                                                           16    7355
XP_006719847                                                           16    7355
XP_006719846                                                           16    7355
XP_006719845                                                           16    7355
XP_006719844                                                           16    7355
XP_006719843                                                           16    7355
XP_006719842                                                           16    7355
XP_005274094                                                           16    7355
XP_006718644                                                           16    7355
XP_005274093                                                           16    7355
XP_005274092                                                           16    7355
XP_006711061                                                           16    7355
XP_006711060                                                           16    7355
XP_005244868                                                           16    7355
NP_001139784                                                           15    9605
NP_705832                                                              15    9605
NP_001171989                                                           15    9605
NP_001171991                                                           15    9605
NP_001171990                                                           15    9605
NP_932766                                                              15    9605
NP_000287                                                              15    9605
NP_001009944                                                           15    9605
NP_004280                                                              15    9605
NP_001159506                                                           15    9605
NP_940940                                                              15    9605
NP_001159507                                                           15    9605
NP_003449                                                              15    9605
NP_004696                                                              15    9605
XP_006721791                                                           15    9605
XP_005256921                                                           15    9605
XP_005256920                                                           15    9605
XP_005255427                                                           15    9605
XP_006720956                                                           15    9605
XP_006720955                                                           15    9605
XP_006720954                                                           15    9605
XP_006720953                                                           15    9605
XP_006720952                                                           15    9605
XP_006713443                                                           15    9605
>NP_003290
          Length = 803

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  QLDGLNSSQ 9
          QLDGLN+SQ
Sbjct: 57 QLDGLNASQ 65
>NP_056377
          Length = 489

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QLDGLNSS 8
           QLDGL+SS
Sbjct: 263 QLDGLSSS 270
>NP_000278
          Length = 980

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S+Q
Sbjct: 832 ELDGLHSTQ 840
>NP_005087
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_001164634
          Length = 495

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_001164633
          Length = 1358

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>NP_963893
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_005262367
          Length = 1358

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_006724778
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_005262366
          Length = 1370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSSQ
Sbjct: 201 DGINSSQ 207
>XP_005249237
          Length = 892

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S+Q
Sbjct: 744 ELDGLHSTQ 752
>NP_001123230
          Length = 512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           +GLNSSQ
Sbjct: 206 EGLNSSQ 212
>NP_071752
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           +GLNSSQ
Sbjct: 206 EGLNSSQ 212
>NP_000042
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QLDGLNS 7
           Q DGLNS
Sbjct: 201 QTDGLNS 207
>NP_004841
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LDGLNS 7
          LDGLNS
Sbjct: 47 LDGLNS 52
>XP_006718907
          Length = 3050

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QLDGLNS 7
           Q DGLNS
Sbjct: 201 QTDGLNS 207
>XP_006718906
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QLDGLNS 7
           Q DGLNS
Sbjct: 201 QTDGLNS 207
>XP_005271619
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QLDGLNS 7
           Q DGLNS
Sbjct: 201 QTDGLNS 207
>XP_005271618
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QLDGLNS 7
           Q DGLNS
Sbjct: 201 QTDGLNS 207
>XP_005246247
          Length = 1417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LDGLNS 7
          LDGLNS
Sbjct: 47 LDGLNS 52
>NP_005643
          Length = 542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GLNSSQ 9
           GLNSSQ
Sbjct: 418 GLNSSQ 423
>NP_001073953
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLDGLNSSQ 9
           QL+G  SSQ
Sbjct: 695 QLEGTESSQ 703
>NP_055872
          Length = 4678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>NP_060105
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSS+
Sbjct: 736 DGMNSSK 742
>XP_005256181
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GLNSSQ 9
           GLNSSQ
Sbjct: 340 GLNSSQ 345
>XP_005256180
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GLNSSQ 9
           GLNSSQ
Sbjct: 418 GLNSSQ 423
>XP_005256179
          Length = 544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GLNSSQ 9
           GLNSSQ
Sbjct: 421 GLNSSQ 426
>XP_005256178
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GLNSSQ 9
           GLNSSQ
Sbjct: 421 GLNSSQ 426
>XP_006719852
          Length = 4752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_005266357
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719851
          Length = 4689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719850
          Length = 4697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719849
          Length = 4703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719848
          Length = 4737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_005266356
          Length = 4755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719847
          Length = 4761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1675 EVDGLNS 1681
>XP_006719846
          Length = 4763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719845
          Length = 4772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719844
          Length = 4789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719843
          Length = 4794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_006719842
          Length = 4797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QLDGLNS 7
            ++DGLNS
Sbjct: 1711 EVDGLNS 1717
>XP_005274094
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSS+
Sbjct: 564 DGMNSSK 570
>XP_006718644
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSS+
Sbjct: 713 DGMNSSK 719
>XP_005274093
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSS+
Sbjct: 713 DGMNSSK 719
>XP_005274092
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG+NSS+
Sbjct: 736 DGMNSSK 742
>XP_006711061
          Length = 1553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLDGLNSSQ 9
           QL+G  SSQ
Sbjct: 609 QLEGTESSQ 617
>XP_006711060
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLDGLNSSQ 9
           QL+G  SSQ
Sbjct: 651 QLEGTESSQ 659
>XP_005244868
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QLDGLNSSQ 9
           QL+G  SSQ
Sbjct: 695 QLEGTESSQ 703
>NP_001139784
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S +
Sbjct: 509 ELDGLDSEK 517
>NP_705832
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S +
Sbjct: 509 ELDGLDSEK 517
>NP_001171989
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DGLNSSQ 9
          DG+NS Q
Sbjct: 48 DGVNSGQ 54
>NP_001171991
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DGLNSSQ 9
          DG+NS Q
Sbjct: 16 DGVNSGQ 22
>NP_001171990
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DGLNSSQ 9
          DG+NS Q
Sbjct: 80 DGVNSGQ 86
>NP_932766
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DGLNSSQ 9
           DG+NS Q
Sbjct: 131 DGVNSGQ 137
>NP_000287
          Length = 4302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4192 QLDGLSVS 4199
>NP_001009944
          Length = 4303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4193 QLDGLSVS 4200
>NP_004280
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DGLNSS 8
           DG+NSS
Sbjct: 293 DGMNSS 298
>NP_001159506
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  LDGLNS 7
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_940940
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  LDGLNS 7
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_001159507
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  LDGLNS 7
          LDG+NS
Sbjct: 51 LDGINS 56
>NP_003449
          Length = 3926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG++SSQ
Sbjct: 688 DGISSSQ 694
>NP_004696
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LDGLNS 7
           LDG+NS
Sbjct: 448 LDGINS 453
>XP_006721791
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLDGLNSSQ 9
           +LD LN+ Q
Sbjct: 707 ELDSLNTQQ 715
>XP_005256921
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S +
Sbjct: 430 ELDGLDSEK 438
>XP_005256920
          Length = 943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLDGLNSSQ 9
           +LDGL+S +
Sbjct: 509 ELDGLDSEK 517
>XP_005255427
          Length = 3288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 3178 QLDGLSVS 3185
>XP_006720956
          Length = 3895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 3785 QLDGLSVS 3792
>XP_006720955
          Length = 4279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4169 QLDGLSVS 4176
>XP_006720954
          Length = 4334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4224 QLDGLSVS 4231
>XP_006720953
          Length = 4339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4229 QLDGLSVS 4236
>XP_006720952
          Length = 4340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QLDGLNSS 8
            QLDGL+ S
Sbjct: 4230 QLDGLSVS 4237
>XP_006713443
          Length = 3970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DGLNSSQ 9
           DG++SSQ
Sbjct: 732 DGISSSQ 738
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.119    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,235
Number of extensions: 704
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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