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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     509
NP_001120972                                                           20     509
XP_006716052                                                           20     509
XP_006716051                                                           20     509
NP_060681                                                              17    3301
XP_006710801                                                           17    3301
NP_055714                                                              17    3301
NP_001002913                                                           16    5631
XP_006717018                                                           16    5631
NP_659489                                                              16    7355
NP_001136197                                                           16    7355
NP_542394                                                              16    7355
NP_112190                                                              15    9605
NP_006539                                                              15    9605
NP_001007226                                                           15    9605
NP_001186681                                                           15    9605
NP_001129524                                                           15    9605
NP_689572                                                              15    9605
NP_001186682                                                           15    9605
NP_066192                                                              15    9605
NP_057715                                                              15    9605
NP_037461                                                              15    9605
NP_079467                                                              15    9605
XP_006724130                                                           15    9605
XP_006724129                                                           15    9605
XP_006723072                                                           15    9605
XP_005258564                                                           15    9605
XP_005258563                                                           15    9605
XP_005258562                                                           15    9605
XP_006713541                                                           15    9605
XP_006713540                                                           15    9605
XP_005245556                                                           15    9605

>NP_000236
          Length = 1390

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLARQLGAS 9
           QLARQ+GAS
Sbjct: 328 QLARQIGAS 336



>NP_001120972
          Length = 1408

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLARQLGAS 9
           QLARQ+GAS
Sbjct: 328 QLARQIGAS 336



>XP_006716052
          Length = 1409

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLARQLGAS 9
           QLARQ+GAS
Sbjct: 347 QLARQIGAS 355



>XP_006716051
          Length = 1427

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLARQLGAS 9
           QLARQ+GAS
Sbjct: 347 QLARQIGAS 355



>NP_060681
          Length = 678

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L RQLGAS
Sbjct: 204 LGRQLGAS 211



>XP_006710801
          Length = 647

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L RQLGAS
Sbjct: 160 LGRQLGAS 167



>NP_055714
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QLARQLGAS 9
           QLA++LGA+
Sbjct: 163 QLAKELGAT 171



>NP_001002913
          Length = 214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QLARQLGAS 9
          QLAR+LG +
Sbjct: 55 QLARRLGVA 63



>XP_006717018
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QLARQLGAS 9
          QLAR+LG +
Sbjct: 68 QLARRLGVA 76



>NP_659489
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QLARQLGA 8
           +L+RQ+GA
Sbjct: 101 ELSRQIGA 108



>NP_001136197
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QLARQLG 7
          +LARQLG
Sbjct: 5  RLARQLG 11



>NP_542394
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QLARQLG 7
          +LARQLG
Sbjct: 5  RLARQLG 11



>NP_112190
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QLARQLGA 8
           Q AR+LGA
Sbjct: 128 QRARELGA 135



>NP_006539
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QLARQLGAS 9
           QLAR  GAS
Sbjct: 452 QLARFAGAS 460



>NP_001007226
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QLARQLGAS 9
           QLAR  GAS
Sbjct: 409 QLARFAGAS 417



>NP_001186681
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 787 LSRQTGAS 794



>NP_001129524
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 776 LSRQTGAS 783



>NP_689572
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 787 LSRQTGAS 794



>NP_001186682
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 787 LSRQTGAS 794



>NP_066192
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L R+LGAS
Sbjct: 156 LKRELGAS 163



>NP_057715
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+AR+LG
Sbjct: 233 QMARELG 239



>NP_037461
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+AR+LG
Sbjct: 233 QMARELG 239



>NP_079467
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+A+QLG
Sbjct: 181 QMAKQLG 187



>XP_006724130
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+AR+LG
Sbjct: 233 QMARELG 239



>XP_006724129
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+AR+LG
Sbjct: 233 QMARELG 239



>XP_006723072
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 658 LSRQTGAS 665



>XP_005258564
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 736 LSRQTGAS 743



>XP_005258563
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 787 LSRQTGAS 794



>XP_005258562
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LARQLGAS 9
           L+RQ GAS
Sbjct: 787 LSRQTGAS 794



>XP_006713541
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QLARQLGAS 9
           QLAR  GAS
Sbjct: 153 QLARFAGAS 161



>XP_006713540
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QLARQLGAS 9
           QLAR  GAS
Sbjct: 196 QLARFAGAS 204



>XP_005245556
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QLARQLG 7
           Q+A+QLG
Sbjct: 181 QMAKQLG 187



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.124    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,576
Number of extensions: 487
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)