Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     299
NP_001185763                                                           20     299
NP_055459                                                              20     299
NP_001002811                                                           20     299
NP_001002812                                                           20     299
XP_006726410                                                           20     299
XP_006711719                                                           20     299
XP_006711717                                                           20     299
XP_006711716                                                           20     299
XP_006711715                                                           20     299
XP_006711714                                                           20     299
XP_006711713                                                           20     299
XP_006711712                                                           20     299
XP_006711711                                                           20     299
XP_006711710                                                           20     299
XP_006711709                                                           20     299
XP_005277503                                                           20     299
XP_005273038                                                           20     299
XP_006711708                                                           20     299
XP_005277500                                                           20     299
XP_006711707                                                           20     299
XP_005277499                                                           20     299
XP_006711706                                                           20     299
XP_006711705                                                           20     299
XP_006711164                                                           20     299
XP_006710144                                                           20     299
NP_001092094                                                           20     509
NP_000372                                                              20     509
NP_150632                                                              20     509
NP_001180206                                                           20     509
NP_001180209                                                           20     509
NP_001180207                                                           20     509
NP_150631                                                              20     509
NP_001180208                                                           20     509
XP_005274595                                                           20     509
XP_006724556                                                           20     509
XP_005274594                                                           20     509
XP_005274593                                                           20     509
XP_006724555                                                           20     509
NP_438112                                                              17    2528
NP_036348                                                              17    2528
NP_001157934                                                           17    2528
XP_005262119                                                           17    2528
NP_001269880                                                           17    4312
NP_001025226                                                           16    5631
NP_001164                                                              16    5631
NP_005483                                                              16    5631
NP_001268659                                                           16    5631
XP_005260696                                                           16    5631
XP_005267693                                                           16    5631
XP_005267692                                                           16    5631
NP_003622                                                              16    7355
NP_001157941                                                           16    7355
NP_001157940                                                           16    7355
NP_861974                                                              16    7355
NP_001258867                                                           16    7355
NP_001401                                                              16    7355
XP_005254320                                                           16    7355
NP_031390                                                              16    7355
NP_002202                                                              15    9605
NP_596867                                                              15    9605
NP_391988                                                              15    9605
NP_115627                                                              15    9605
NP_976048                                                              15    9605
NP_055704                                                              15    9605
NP_001229236                                                           15    9605
NP_001229238                                                           15    9605
NP_065796                                                              15    9605
XP_006718583                                                           15    9605
XP_006718582                                                           15    9605
XP_005252505                                                           15    9605
XP_006717425                                                           15    9605
XP_005252402                                                           15    9605
XP_005249302                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>NP_001185763
          Length = 2362

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 368 QLADAKQCV 376
>NP_055459
          Length = 2346

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 368 QLADAKQCV 376
>NP_001002811
          Length = 1132

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>NP_001002812
          Length = 969

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 368 QLADAKQCV 376
>XP_006726410
          Length = 2087

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 443 QLADAKQCV 451
>XP_006711719
          Length = 2302

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>XP_006711717
          Length = 2385

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>XP_006711716
          Length = 2411

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>XP_006711715
          Length = 2428

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 368 QLADAKQCV 376
>XP_006711714
          Length = 2429

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 368 QLADAKQCV 376
>XP_006711713
          Length = 2432

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 371 QLADAKQCV 379
>XP_006711712
          Length = 2473

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711711
          Length = 2482

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711710
          Length = 2494

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>XP_006711709
          Length = 2495

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 434 QLADAKQCV 442
>XP_005277503
          Length = 2498

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_005273038
          Length = 2509

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711708
          Length = 2512

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_005277500
          Length = 2525

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711707
          Length = 2553

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_005277499
          Length = 2561

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711706
          Length = 2591

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711705
          Length = 2592

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>XP_006711164
          Length = 2087

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 443 QLADAKQCV 451
>XP_006710144
          Length = 564

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           QLA+AKQCV
Sbjct: 531 QLADAKQCV 539
>NP_001092094
          Length = 667

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 298 QIANCKQCI 306
>NP_000372
          Length = 667

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 298 QIANCKQCI 306
>NP_150632
          Length = 667

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 298 QIANCKQCI 306
>NP_001180206
          Length = 667

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 298 QIANCKQCI 306
>NP_001180209
          Length = 451

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 260 QIANCKQCI 268
>NP_001180207
          Length = 540

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 349 QIANCKQCI 357
>NP_150631
          Length = 629

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 260 QIANCKQCI 268
>NP_001180208
          Length = 489

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 298 QIANCKQCI 306
>XP_005274595
          Length = 540

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 349 QIANCKQCI 357
>XP_006724556
          Length = 680

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 311 QIANCKQCI 319
>XP_005274594
          Length = 718

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 349 QIANCKQCI 357
>XP_005274593
          Length = 718

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 349 QIANCKQCI 357
>XP_006724555
          Length = 718

 Score = 19.6 bits (39), Expect =   509
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN KQC+
Sbjct: 349 QIANCKQCI 357
>NP_438112
          Length = 705

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN +QC+
Sbjct: 318 QVANCRQCL 326
>NP_036348
          Length = 735

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN +QC+
Sbjct: 318 QVANCRQCL 326
>NP_001157934
          Length = 5335

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QLANAKQCV 9
            Q+ N KQCV
Sbjct: 4992 QIWNGKQCV 5000
>XP_005262119
          Length = 715

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QLANAKQCV 9
           Q+AN +QC+
Sbjct: 298 QVANCRQCL 306
>NP_001269880
          Length = 209

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  QLANAKQCV 9
          +LAN ++C+
Sbjct: 48 ELANVQECI 56
>NP_001025226
          Length = 1502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QLANAKQC 8
           QLAN  QC
Sbjct: 720 QLANKLQC 727
>NP_001164
          Length = 1501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QLANAKQC 8
           QLAN  QC
Sbjct: 720 QLANKLQC 727
>NP_005483
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ANAKQCV 9
          AN KQC+
Sbjct: 43 ANVKQCL 49
>NP_001268659
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ANAKQCV 9
          AN KQC+
Sbjct: 43 ANVKQCL 49
>XP_005260696
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ANAKQCV 9
          AN KQC+
Sbjct: 43 ANVKQCL 49
>XP_005267693
          Length = 1502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QLANAKQC 8
           QLAN  QC
Sbjct: 720 QLANKLQC 727
>XP_005267692
          Length = 1502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QLANAKQC 8
           QLAN  QC
Sbjct: 720 QLANKLQC 727
>NP_003622
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QLANAKQ 7
           +LANAKQ
Sbjct: 215 KLANAKQ 221
>NP_001157941
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4  NAKQC 8
          NAKQC
Sbjct: 44 NAKQC 48
>NP_001157940
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4  NAKQC 8
          NAKQC
Sbjct: 44 NAKQC 48
>NP_861974
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4  NAKQC 8
          NAKQC
Sbjct: 44 NAKQC 48
>NP_001258867
          Length = 2845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LANAKQC 8
           LAN+ QC
Sbjct: 960 LANSSQC 966
>NP_001401
          Length = 2778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LANAKQC 8
           LAN+ QC
Sbjct: 893 LANSSQC 899
>XP_005254320
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4  NAKQC 8
          NAKQC
Sbjct: 36 NAKQC 40
>NP_031390
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4  NAKQC 8
          NAKQC
Sbjct: 36 NAKQC 40
>NP_002202
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3  ANAKQC 8
          ANAK C
Sbjct: 30 ANAKSC 35
>NP_596867
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3  ANAKQC 8
          ANAK C
Sbjct: 30 ANAKSC 35
>NP_391988
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3  ANAKQC 8
          ANAK C
Sbjct: 30 ANAKSC 35
>NP_115627
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QLANAK 6
           QLANAK
Sbjct: 259 QLANAK 264
>NP_976048
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  NAKQCV 9
          NAK CV
Sbjct: 56 NAKNCV 61
>NP_055704
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLANAKQCV 9
           QLA  +QC+
Sbjct: 470 QLAKFRQCL 478
>NP_001229236
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLANAKQCV 9
           QLA  +QC+
Sbjct: 470 QLAKFRQCL 478
>NP_001229238
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLANAKQCV 9
           QLA  +QC+
Sbjct: 438 QLAKFRQCL 446
>NP_065796
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           ++AN+++CV
Sbjct: 101 RVANSQKCV 109
>XP_006718583
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QLANAK 6
           QLANAK
Sbjct: 181 QLANAK 186
>XP_006718582
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QLANAK 6
           QLANAK
Sbjct: 259 QLANAK 264
>XP_005252505
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3  ANAKQC 8
          ANAK C
Sbjct: 30 ANAKSC 35
>XP_006717425
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLANAKQCV 9
           QLA  +QC+
Sbjct: 470 QLAKFRQCL 478
>XP_005252402
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QLANAKQCV 9
           QLA  +QC+
Sbjct: 470 QLAKFRQCL 478
>XP_005249302
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QLANAKQCV 9
           ++AN+++CV
Sbjct: 101 RVANSQKCV 109
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.120    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 456,441
Number of extensions: 555
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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