Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060427                                                              19     869
NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726410                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_006710143                                                           18    1482
XP_006710142                                                           18    1482
XP_006710141                                                           18    1482
XP_005258887                                                           18    1935
XP_005258886                                                           18    1935
XP_006723240                                                           18    1935
XP_006723239                                                           18    1935
NP_001123544                                                           18    1935
NP_001018865                                                           17    3301
NP_001018864                                                           17    3301
XP_006721539                                                           17    3301
XP_005256596                                                           17    3301
XP_006721538                                                           17    3301
XP_005247970                                                           17    3301
XP_005247969                                                           17    3301
XP_005247968                                                           17    3301
NP_683723                                                              17    3301
NP_055779                                                              17    3301
NP_079245                                                              16    7355
NP_001165644                                                           16    7355
NP_001123543                                                           16    7355
NP_110436                                                              16    7355
XP_006723241                                                           16    7355
XP_006719685                                                           16    7355
XP_006719684                                                           16    7355
XP_005246922                                                           16    7355
NP_037465                                                              16    7355
NP_000115                                                              15    9605
NP_001248395                                                           15    9605
>NP_060427
          Length = 632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QLALRLSRE 9
           QLALRLSR+
Sbjct: 242 QLALRLSRQ 250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 215 QLALAMSRE 223
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1521 LALRLSRE 1528
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1565 LALRLSRE 1572
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1565 LALRLSRE 1572
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1368 LALRLSRE 1375
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1521 LALRLSRE 1528
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LALRLSRE 9
           LALRLSRE
Sbjct: 572 LALRLSRE 579
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1521 LALRLSRE 1528
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1630 LALRLSRE 1637
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1564 LALRLSRE 1571
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1565 LALRLSRE 1572
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1568 LALRLSRE 1575
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1618 LALRLSRE 1625
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1630 LALRLSRE 1637
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1631 LALRLSRE 1638
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1727 LALRLSRE 1734
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1728 LALRLSRE 1735
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LALRLSRE 9
            LALRLSRE
Sbjct: 1368 LALRLSRE 1375
>XP_006710143
          Length = 562

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LALRLSRE 9
           LALRLSRE
Sbjct: 407 LALRLSRE 414
>XP_006710142
          Length = 671

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LALRLSRE 9
           LALRLSRE
Sbjct: 516 LALRLSRE 523
>XP_006710141
          Length = 672

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LALRLSRE 9
           LALRLSRE
Sbjct: 517 LALRLSRE 524
>XP_005258887
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL LSRE
Sbjct: 214 QLALSLSRE 222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 189 QLALAMSKE 197
>XP_005258886
          Length = 576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL LSRE
Sbjct: 214 QLALSLSRE 222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 189 QLALAMSKE 197
>XP_006723240
          Length = 635

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL LSRE
Sbjct: 274 QLALSLSRE 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 249 QLALAMSKE 257
>XP_006723239
          Length = 636

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL LSRE
Sbjct: 274 QLALSLSRE 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 249 QLALAMSKE 257
>NP_001123544
          Length = 576

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL LSRE
Sbjct: 214 QLALSLSRE 222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 189 QLALAMSKE 197
>NP_001018865
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           Q A+RLSRE
Sbjct: 224 QRAMRLSRE 232
>NP_001018864
          Length = 598

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           Q A+RLSRE
Sbjct: 357 QRAMRLSRE 365
>XP_006721539
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 224 QLALAMSRE 232
>XP_005256596
          Length = 454

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 94  QLALAMSRE 102
>XP_006721538
          Length = 578

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 224 QLALAMSRE 232
>XP_005247970
          Length = 378

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           Q A+RLSRE
Sbjct: 357 QRAMRLSRE 365
>XP_005247969
          Length = 414

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           Q A+RLSRE
Sbjct: 173 QRAMRLSRE 181
>XP_005247968
          Length = 474

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           Q A+RLSRE
Sbjct: 357 QRAMRLSRE 365
>NP_683723
          Length = 584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 224 QLALAMSRE 232
>NP_055779
          Length = 641

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +SRE
Sbjct: 281 QLALAMSRE 289
>NP_079245
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 204 AIRLSRE 210
>NP_001165644
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 204 AIRLSRE 210
>NP_001123543
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 300 QLALAMSKE 308
>NP_110436
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 205 AIRLSRE 211
>XP_006723241
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 249 QLALAMSKE 257
>XP_006719685
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 205 AIRLSRE 211
>XP_006719684
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 205 AIRLSRE 211
>XP_005246922
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRLSRE 9
           A+RLSRE
Sbjct: 236 AIRLSRE 242
>NP_037465
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QLALRLSRE 9
           QLAL +S+E
Sbjct: 189 QLALAMSKE 197
>NP_000115
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALRLSRE 9
            ALRLSR+
Sbjct: 1296 ALRLSRQ 1302
>NP_001248395
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QLALRLSRE 9
          Q+ALR SR+
Sbjct: 36 QVALRSSRQ 44
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.134    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 287,299
Number of extensions: 412
Number of successful extensions: 60
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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