Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     390
NP_001120972                                                           20     390
XP_006716052                                                           20     390
XP_006716051                                                           20     390
NP_001267482                                                           17    4312
NP_001267479                                                           17    4312
NP_001267478                                                           17    4312
NP_001267476                                                           17    4312
NP_057953                                                              17    4312
NP_001267477                                                           17    4312
NP_001267481                                                           17    4312
NP_001267483                                                           17    4312
NP_112569                                                              17    4312
NP_001140099                                                           17    4312
NP_001140062                                                           17    4312
XP_005251538                                                           17    4312
XP_006714353                                                           17    4312
NP_005451                                                              16    5631
XP_006714798                                                           16    5631
XP_006714797                                                           16    5631
XP_005272195                                                           16    5631
XP_005272196                                                           16    5631
NP_777367                                                              16    7355
NP_001182723                                                           16    7355
NP_003981                                                              16    7355
NP_003980                                                              16    7355
NP_000269                                                              16    7355
NP_003978                                                              16    7355
NP_003979                                                              16    7355
NP_443721                                                              16    7355
NP_694955                                                              16    7355
NP_001159698                                                           16    7355
NP_001027559                                                           16    7355
NP_001027558                                                           16    7355
NP_000447                                                              16    7355
NP_071328                                                              16    7355
NP_060688                                                              16    7355
XP_006721357                                                           16    7355
XP_006721356                                                           16    7355
XP_005269169                                                           16    7355
XP_005271571                                                           16    7355
XP_005271958                                                           16    7355
XP_005246148                                                           16    7355
XP_005246145                                                           16    7355
XP_006712675                                                           16    7355
NP_001153685                                                           16    7355
NP_112583                                                              16    7355
NP_859072                                                              16    7355
NP_057123                                                              15    9605
NP_056127                                                              15    9605
NP_055789                                                              15    9605
XP_005252486                                                           15    9605
XP_005252485                                                           15    9605
XP_005252484                                                           15    9605
XP_005252483                                                           15    9605
XP_006714407                                                           15    9605
XP_006714406                                                           15    9605
XP_006714405                                                           15    9605
XP_005263349                                                           15    9605
XP_005263348                                                           15    9605
XP_005263347                                                           15    9605
XP_005263346                                                           15    9605
XP_005263345                                                           15    9605
XP_005263344                                                           15    9605
XP_005263343                                                           15    9605
XP_005263342                                                           15    9605
XP_005263341                                                           15    9605
XP_005263340                                                           15    9605
XP_005263339                                                           15    9605
NP_001138343                                                           15    9605
>NP_000236
          Length = 1390

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QKVAEYKIG 9
          QKVAEYK G
Sbjct: 79 QKVAEYKTG 87
>NP_001120972
          Length = 1408

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QKVAEYKIG 9
          QKVAEYK G
Sbjct: 79 QKVAEYKTG 87
>XP_006716052
          Length = 1409

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QKVAEYKIG 9
           QKVAEYK G
Sbjct: 98  QKVAEYKTG 106
>XP_006716051
          Length = 1427

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QKVAEYKIG 9
           QKVAEYK G
Sbjct: 98  QKVAEYKTG 106
>NP_001267482
          Length = 319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267479
          Length = 295

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267478
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267476
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_057953
          Length = 391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267477
          Length = 362

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267481
          Length = 328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_001267483
          Length = 348

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 97  EKIAEYK 103
>NP_112569
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVAEY  G
Sbjct: 230 QKVAEYVHG 238
>NP_001140099
          Length = 441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVAEY  G
Sbjct: 172 QKVAEYVHG 180
>NP_001140062
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVAEY  G
Sbjct: 224 QKVAEYVHG 232
>XP_005251538
          Length = 390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QKVAEYK 7
           +K+AEYK
Sbjct: 96  EKIAEYK 102
>XP_006714353
          Length = 459

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVAEY  G
Sbjct: 190 QKVAEYVHG 198
>NP_005451
          Length = 919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKV EY+ G
Sbjct: 100 QKVVEYQKG 108
>XP_006714798
          Length = 919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKV EY+ G
Sbjct: 100 QKVVEYQKG 108
>XP_006714797
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKV EY+ G
Sbjct: 100 QKVVEYQKG 108
>XP_005272195
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKV EY+ G
Sbjct: 100 QKVVEYQKG 108
>XP_005272196
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKV EY+ G
Sbjct: 100 QKVVEYQKG 108
>NP_777367
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           +K+A YK G
Sbjct: 166 EKIANYKEG 174
>NP_001182723
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           +K+A YK G
Sbjct: 179 EKIANYKEG 187
>NP_003981
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KVAEYK 7
           K+AEYK
Sbjct: 98  KIAEYK 103
>NP_003980
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KVAEYK 7
           K+AEYK
Sbjct: 98  KIAEYK 103
>NP_000269
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KVAEYK 7
           K+AEYK
Sbjct: 98  KIAEYK 103
>NP_003978
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KVAEYK 7
           K+AEYK
Sbjct: 98  KIAEYK 103
>NP_003979
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KVAEYK 7
           K+AEYK
Sbjct: 98  KIAEYK 103
>NP_443721
          Length = 120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QKVAEYKIG 9
          +K+A YK G
Sbjct: 90 EKIANYKEG 98
>NP_694955
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QKVAEYKI 8
           +KVAEY I
Sbjct: 700 KKVAEYTI 707
>NP_001159698
          Length = 960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QKVAEYKI 8
           +KVAEY I
Sbjct: 674 KKVAEYTI 681
>NP_001027559
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VAEYKIG 9
           +A+YKIG
Sbjct: 152 LAQYKIG 158
>NP_001027558
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VAEYKIG 9
           +A+YKIG
Sbjct: 152 LAQYKIG 158
>NP_000447
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VAEYKIG 9
           +A+YKIG
Sbjct: 152 LAQYKIG 158
>NP_071328
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QKVAEY 6
           QK+AEY
Sbjct: 213 QKIAEY 218
>NP_060688
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKVAEYKIG 9
            Q + EYK+G
Sbjct: 1052 QPLREYKLG 1060
>XP_006721357
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVA  K+G
Sbjct: 897 QKVANEKLG 905
>XP_006721356
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVA  K+G
Sbjct: 897 QKVANEKLG 905
>XP_005269169
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VAEYKIG 9
           +A+YKIG
Sbjct: 159 LAQYKIG 165
>XP_005271571
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QKVAEYKI 8
          QK+A YK+
Sbjct: 19 QKLARYKL 26
>XP_005271958
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QKVAEYKI 8
           +KVAEY I
Sbjct: 655 KKVAEYTI 662
>XP_005246148
          Length = 1108

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           Q + EYK+G
Sbjct: 913 QPLREYKLG 921
>XP_005246145
          Length = 1236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKVAEYKIG 9
            Q + EYK+G
Sbjct: 1041 QPLREYKLG 1049
>XP_006712675
          Length = 1248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKVAEYKIG 9
            Q + EYK+G
Sbjct: 1053 QPLREYKLG 1061
>NP_001153685
          Length = 882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVA  K+G
Sbjct: 752 QKVANEKLG 760
>NP_112583
          Length = 1007

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QKVAEYKIG 9
           QKVA  K+G
Sbjct: 897 QKVANEKLG 905
>NP_859072
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QKVAEYKI 8
          QK+A YK+
Sbjct: 19 QKLARYKL 26
>NP_057123
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  QKVAEYKI 8
          QK+  YKI
Sbjct: 35 QKIRHYKI 42
>NP_056127
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>NP_055789
          Length = 1556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QKVAEYK 7
           QKV +YK
Sbjct: 579 QKVCQYK 585
>XP_005252486
          Length = 1407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QKVAEYK 7
           QKV +YK
Sbjct: 420 QKVCQYK 426
>XP_005252485
          Length = 1622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QKVAEYK 7
           QKV +YK
Sbjct: 635 QKVCQYK 641
>XP_005252484
          Length = 1566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QKVAEYK 7
           QKV +YK
Sbjct: 579 QKVCQYK 585
>XP_005252483
          Length = 1612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   QKVAEYK 7
           QKV +YK
Sbjct: 635 QKVCQYK 641
>XP_006714407
          Length = 5004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2998 AEYKMG 3003
>XP_006714406
          Length = 3680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_006714405
          Length = 4103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2076 AEYKMG 2081
>XP_005263349
          Length = 4410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2383 AEYKMG 2388
>XP_005263348
          Length = 4443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2416 AEYKMG 2421
>XP_005263347
          Length = 4640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_005263346
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2956 AEYKMG 2961
>XP_005263345
          Length = 4991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_005263344
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_005263343
          Length = 5009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2982 AEYKMG 2987
>XP_005263342
          Length = 5025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2998 AEYKMG 3003
>XP_005263341
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_005263340
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>XP_005263339
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    AEYKIG 9
            AEYK+G
Sbjct: 2999 AEYKMG 3004
>NP_001138343
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QKVAEYKIG 9
          QK+ E+K G
Sbjct: 76 QKIVEWKPG 84
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.132    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,690
Number of extensions: 641
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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