Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              22      79
NP_006452                                                              17    3301
XP_006715715                                                           17    3301
NP_064623                                                              17    4312
NP_057336                                                              17    4312
NP_001035784                                                           17    4312
XP_006718596                                                           17    4312
XP_006712120                                                           17    4312
XP_005264512                                                           17    4312
XP_005264511                                                           17    4312
XP_006712119                                                           17    4312
XP_005264510                                                           17    4312
XP_006712118                                                           17    4312
XP_005264509                                                           17    4312
XP_005264508                                                           17    4312
XP_006712117                                                           17    4312
XP_005264507                                                           17    4312
XP_005264506                                                           17    4312
NP_001087195                                                           16    5631
NP_001078955                                                           16    5631
NP_005401                                                              16    5631
NP_001004471                                                           16    5631
NP_056197                                                              16    7355
NP_001155000                                                           16    7355
NP_075463                                                              16    7355
XP_005261542                                                           16    7355
XP_005267560                                                           16    7355
XP_005267559                                                           16    7355
XP_006719812                                                           16    7355
NP_777592                                                              16    7355
NP_001271230                                                           15    9605
NP_001271231                                                           15    9605
NP_940966                                                              15    9605
NP_061155                                                              15    9605
NP_848599                                                              15    9605
NP_056083                                                              15    9605
NP_001245243                                                           15    9605
XP_006715810                                                           15    9605
XP_006715809                                                           15    9605
XP_005247302                                                           15    9605
XP_006713081                                                           15    9605
XP_006712935                                                           15    9605
XP_006712934                                                           15    9605
XP_006712933                                                           15    9605
XP_005246694                                                           15    9605
NP_852118                                                              15    9605
>NP_000312
          Length = 928

 Score = 22.3 bits (46), Expect =    79
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QKINQMLCN 9
           QKINQM+CN
Sbjct: 846 QKINQMVCN 854
>NP_006452
          Length = 1193

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QKINQMLC 8
            +K+NQ LC
Sbjct: 1028 EKLNQALC 1035
>XP_006715715
          Length = 2023

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QKINQMLC 8
            +K+NQ LC
Sbjct: 2009 RKVNQSLC 2016
>NP_064623
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QKINQMLCN 9
          QK+ + LCN
Sbjct: 17 QKLMEFLCN 25
>NP_057336
          Length = 4857

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>NP_001035784
          Length = 918

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QKINQMLCN 9
          QK+ + LCN
Sbjct: 17 QKLMEFLCN 25
>XP_006718596
          Length = 922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QKINQMLCN 9
          QK+ + LCN
Sbjct: 17 QKLMEFLCN 25
>XP_006712120
          Length = 4812

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264512
          Length = 4840

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264511
          Length = 4847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_006712119
          Length = 4851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264510
          Length = 4861

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_006712118
          Length = 4864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264509
          Length = 4870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264508
          Length = 4875

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_006712117
          Length = 4878

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264507
          Length = 4880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>XP_005264506
          Length = 4884

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           K+N  LCN
Sbjct: 771 KLNSALCN 778
>NP_001087195
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INQMLC 8
           INQ+LC
Sbjct: 312 INQLLC 317
>NP_001078955
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INQMLC 8
           INQ+LC
Sbjct: 282 INQLLC 287
>NP_005401
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INQMLC 8
           INQ+LC
Sbjct: 282 INQLLC 287
>NP_001004471
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QKINQMLCN 9
           Q+IN  LC+
Sbjct: 177 QEINHFLCD 185
>NP_056197
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKINQMLCN 9
            QK+ Q+ CN
Sbjct: 1848 QKLLQLSCN 1856
>NP_001155000
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QKINQMLCN 9
           QKI+  +CN
Sbjct: 592 QKISSDICN 600
>NP_075463
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    INQMLCN 9
            INQ++C+
Sbjct: 2688 INQLMCD 2694
>XP_005261542
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  QKINQMLC 8
          + +N+MLC
Sbjct: 7  KNLNEMLC 14
>XP_005267560
          Length = 2563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKINQMLCN 9
            QK+ Q+ CN
Sbjct: 1801 QKLLQLSCN 1809
>XP_005267559
          Length = 2610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QKINQMLCN 9
            QK+ Q+ CN
Sbjct: 1848 QKLLQLSCN 1856
>XP_006719812
          Length = 3019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    INQMLCN 9
            INQ++C+
Sbjct: 2688 INQLMCD 2694
>NP_777592
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   QKINQMLC 8
           + +N+MLC
Sbjct: 193 KNLNEMLC 200
>NP_001271230
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKINQML 7
            QK+NQ+L
Sbjct: 1063 QKLNQVL 1069
>NP_001271231
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKINQML 7
            QK+NQ+L
Sbjct: 1062 QKLNQVL 1068
>NP_940966
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QKINQML 7
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_061155
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKINQML 7
            QK+NQ+L
Sbjct: 1100 QKLNQVL 1106
>NP_848599
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QKINQML 7
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_056083
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1    QKINQMLC 8
            +++N++LC
Sbjct: 2174 EQVNEILC 2181
>NP_001245243
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  QKINQMLC 8
          +KIN++ C
Sbjct: 3  KKINKLFC 10
>XP_006715810
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKINQML 7
            QK+NQ+L
Sbjct: 1081 QKLNQVL 1087
>XP_006715809
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QKINQML 7
            QK+NQ+L
Sbjct: 1118 QKLNQVL 1124
>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1    QKINQMLC 8
            +++N++LC
Sbjct: 2179 EQVNEILC 2186
>XP_006713081
          Length = 3964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QKINQML 7
          QKINQ++
Sbjct: 51 QKINQLV 57
>XP_006712935
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           KIN+  CN
Sbjct: 795 KINEEKCN 802
>XP_006712934
          Length = 1583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           KIN+  CN
Sbjct: 691 KINEEKCN 698
>XP_006712933
          Length = 1687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           KIN+  CN
Sbjct: 795 KINEEKCN 802
>XP_005246694
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  QKINQMLC 8
          +KIN++ C
Sbjct: 3  KKINKLFC 10
>NP_852118
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KINQMLCN 9
           KIN+  CN
Sbjct: 792 KINEEKCN 799
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.130    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 514,321
Number of extensions: 840
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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