Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1135
NP_001171146                                                           18    1135
NP_620169                                                              18    1135
XP_005261433                                                           18    1135
XP_005271621                                                           18    1135
XP_006718907                                                           18    1135
XP_006718906                                                           18    1135
XP_005271619                                                           18    1135
XP_005271618                                                           18    1135
NP_060037                                                              18    1482
XP_006712108                                                           18    1482
XP_005264472                                                           18    1482
XP_005264470                                                           18    1482
XP_005264469                                                           18    1482
NP_001020130                                                           17    4312
NP_005709                                                              17    4312
NP_001020131                                                           17    4312
NP_001185709                                                           17    4312
NP_001185722                                                           17    4312
NP_056360                                                              16    5631
NP_001185808                                                           16    5631
NP_036237                                                              16    5631
NP_620477                                                              16    5631
NP_620476                                                              16    5631
XP_006713805                                                           16    5631
XP_005269415                                                           16    5631
XP_005269414                                                           16    5631
NP_055690                                                              16    7355
NP_037444                                                              16    7355
NP_001093646                                                           16    7355
NP_997281                                                              16    7355
XP_005259935                                                           16    7355
XP_005259934                                                           16    7355
XP_005259933                                                           16    7355
XP_005259931                                                           16    7355
XP_005259930                                                           16    7355
XP_006710739                                                           16    7355
XP_005270979                                                           16    7355
NP_056972                                                              16    7355
NP_055730                                                              15    9605
NP_006720                                                              15    9605
NP_001242982                                                           15    9605
NP_009293                                                              15    9605
NP_057525                                                              15    9605
NP_055510                                                              15    9605
NP_573444                                                              15    9605
NP_078802                                                              15    9605
NP_620641                                                              15    9605
XP_005256934                                                           15    9605
XP_006721670                                                           15    9605
XP_006717494                                                           15    9605
XP_006717493                                                           15    9605
XP_006717492                                                           15    9605
XP_006717491                                                           15    9605
XP_006717490                                                           15    9605
XP_006717489                                                           15    9605
XP_006717488                                                           15    9605
XP_006717487                                                           15    9605
XP_006717486                                                           15    9605
XP_005273659                                                           15    9605
XP_006716448                                                           15    9605
XP_006716447                                                           15    9605
XP_006716446                                                           15    9605
XP_006716445                                                           15    9605
XP_006716444                                                           15    9605
XP_005247998                                                           15    9605
XP_005264415                                                           15    9605
XP_005264414                                                           15    9605
XP_006710957                                                           15    9605
NP_073586                                                              15    9605
>NP_000042
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 499 QIQAENFGL 507
>NP_001171146
          Length = 315

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           QI  ENFFL
Sbjct: 101 QISTENFFL 109
>NP_620169
          Length = 429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           QI  ENFFL
Sbjct: 215 QISTENFFL 223
>XP_005261433
          Length = 289

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  QIQAENFFL 9
          QI  ENFFL
Sbjct: 75 QISTENFFL 83
>XP_005271621
          Length = 2708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 151 QIQAENFGL 159
>XP_006718907
          Length = 3050

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 499 QIQAENFGL 507
>XP_006718906
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 499 QIQAENFGL 507
>XP_005271619
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 499 QIQAENFGL 507
>XP_005271618
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           QIQAENF L
Sbjct: 499 QIQAENFGL 507
>NP_060037
          Length = 390

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QIQAENFF 8
           +IQA+NFF
Sbjct: 338 EIQAQNFF 345
>XP_006712108
          Length = 196

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QIQAENFF 8
           +IQA+NFF
Sbjct: 144 EIQAQNFF 151
>XP_005264472
          Length = 293

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QIQAENFF 8
           +IQA+NFF
Sbjct: 241 EIQAQNFF 248
>XP_005264470
          Length = 293

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QIQAENFF 8
           +IQA+NFF
Sbjct: 241 EIQAQNFF 248
>XP_005264469
          Length = 293

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QIQAENFF 8
           +IQA+NFF
Sbjct: 241 EIQAQNFF 248
>NP_001020130
          Length = 78

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IQAENFFL 9
          ++AENFF+
Sbjct: 6  MRAENFFI 13
>NP_005709
          Length = 168

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IQAENFFL 9
           ++AENFF+
Sbjct: 96  MRAENFFI 103
>NP_001020131
          Length = 78

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IQAENFFL 9
          ++AENFF+
Sbjct: 6  MRAENFFI 13
>NP_001185709
          Length = 187

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IQAENFFL 9
           ++AENFF+
Sbjct: 115 MRAENFFI 122
>NP_001185722
          Length = 625

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IQAENFFL 9
           ++AENFF+
Sbjct: 96  MRAENFFI 103
>NP_056360
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           Q+QA+NF L
Sbjct: 237 QLQAKNFEL 245
>NP_001185808
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QIQAENFFL 9
           Q+QA+NF L
Sbjct: 286 QLQAKNFEL 294
>NP_036237
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAENFFL 9
           ++ENFFL
Sbjct: 182 ESENFFL 188
>NP_620477
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAENFFL 9
           ++ENFFL
Sbjct: 182 ESENFFL 188
>NP_620476
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAENFFL 9
           ++ENFFL
Sbjct: 182 ESENFFL 188
>XP_006713805
          Length = 1074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   IQAENFFL 9
           I  ENFFL
Sbjct: 976 ITVENFFL 983
>XP_005269415
          Length = 1229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    IQAENFFL 9
            I  ENFFL
Sbjct: 1131 ITVENFFL 1138
>XP_005269414
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    IQAENFFL 9
            I  ENFFL
Sbjct: 1158 ITVENFFL 1165
>NP_055690
          Length = 1648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    QIQAENF 7
            Q+Q ENF
Sbjct: 1482 QVQEENF 1488
>NP_037444
          Length = 719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 247 QLQEENFRL 255
>NP_001093646
          Length = 717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 247 QLQEENFRL 255
>NP_997281
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QIQAENF 7
           Q+Q+ENF
Sbjct: 262 QMQSENF 268
>XP_005259935
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 174 QLQEENFRL 182
>XP_005259934
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 174 QLQEENFRL 182
>XP_005259933
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 174 QLQEENFRL 182
>XP_005259931
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 247 QLQEENFRL 255
>XP_005259930
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 247 QLQEENFRL 255
>XP_006710739
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 256 QLQEENFRL 264
>XP_005270979
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 256 QLQEENFRL 264
>NP_056972
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QIQAENFFL 9
           Q+Q ENF L
Sbjct: 256 QLQEENFRL 264
>NP_055730
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1138 QLQSENMLL 1146
>NP_006720
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AEN+FL
Sbjct: 421 AENYFL 426
>NP_001242982
          Length = 1709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1137 QLQSENMLL 1145
>NP_009293
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AEN+FL
Sbjct: 421 AENYFL 426
>NP_057525
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    IQAENFF 8
            +QA+NF+
Sbjct: 1027 LQADNFY 1033
>NP_055510
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1044 QLQSENMLL 1052
>NP_573444
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IQAENF 7
           +QAENF
Sbjct: 538 LQAENF 543
>NP_078802
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IQAENF 7
           +QAENF
Sbjct: 508 LQAENF 513
>NP_620641
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IQAENF 7
           +QAENF
Sbjct: 539 LQAENF 544
>XP_005256934
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1044 QLQSENMLL 1052
>XP_006721670
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1044 QLQSENMLL 1052
>XP_006717494
          Length = 1571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 999  QLQSENMLL 1007
>XP_006717493
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1038 QLQSENMLL 1046
>XP_006717492
          Length = 1635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1500 QLQSENMLL 1508
>XP_006717491
          Length = 1677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1105 QLQSENMLL 1113
>XP_006717490
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1219 QLQSENMLL 1227
>XP_006717489
          Length = 1945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1500 QLQSENMLL 1508
>XP_006717488
          Length = 2031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1500 QLQSENMLL 1508
>XP_006717487
          Length = 2071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1499 QLQSENMLL 1507
>XP_006717486
          Length = 2072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QIQAENFFL 9
            Q+Q+EN  L
Sbjct: 1500 QLQSENMLL 1508
>XP_005273659
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 369 AENFFV 374
>XP_006716448
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 266 AENFFV 271
>XP_006716447
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 266 AENFFV 271
>XP_006716446
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 311 AENFFV 316
>XP_006716445
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 311 AENFFV 316
>XP_006716444
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 369 AENFFV 374
>XP_005247998
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IQAENFFL 9
           +QAE+F L
Sbjct: 671 VQAESFLL 678
>XP_005264415
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   IQAENFF 8
           +QA+NF+
Sbjct: 962 LQADNFY 968
>XP_005264414
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   IQAENFF 8
           +QA+NF+
Sbjct: 969 LQADNFY 975
>XP_006710957
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IQAENF 7
           +QAENF
Sbjct: 509 LQAENF 514
>NP_073586
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AENFFL 9
           AENFF+
Sbjct: 369 AENFFV 374
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.144    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 475,657
Number of extensions: 448
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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