Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_003290                                                              16    7355
NP_000851                                                              15    9605
NP_001139288                                                           15    9605
NP_001243234                                                           15    9605
NP_060087                                                              15    9605
NP_000426                                                              15    9605
NP_057329                                                              15    9605
NP_056325                                                              15    9605
NP_115925                                                              15    9605
NP_065880                                                              15    9605
NP_001129392                                                           15    9605
NP_001193486                                                           15    9605
NP_620140                                                              15    9605
XP_005259981                                                           15    9605
XP_005256653                                                           15    9605
XP_005256652                                                           15    9605
XP_006717367                                                           15    9605
XP_005251580                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QILVKNAG 8
            QILVKNAG
Sbjct: 2796 QILVKNAG 2803
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QILVKNAG 8
            QILVKNAG
Sbjct: 2788 QILVKNAG 2795
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QILVKNAG 8
            QILVKNAG
Sbjct: 2749 QILVKNAG 2756
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QILVKNAG 8
            QILVKNAG
Sbjct: 2828 QILVKNAG 2835
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QILVKNAG 8
            QILVKNAG
Sbjct: 2841 QILVKNAG 2848
>NP_003290
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LVKNAGT 9
           LVKN GT
Sbjct: 159 LVKNLGT 165
>NP_000851
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ILVKNAG 8
          ILV NAG
Sbjct: 87 ILVNNAG 93
>NP_001139288
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ILVKNAG 8
          ILV NAG
Sbjct: 87 ILVNNAG 93
>NP_001243234
          Length = 143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ILVKNAG 8
          ILV NAG
Sbjct: 87 ILVNNAG 93
>NP_060087
          Length = 2555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QILVKNAGT 9
            QIL++N  T
Sbjct: 1978 QILIRNRAT 1986
>NP_000426
          Length = 2321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QILVKNAGT 9
            QIL++N  T
Sbjct: 1889 QILIRNRST 1897
>NP_057329
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ILVKNAG 8
           ILV NAG
Sbjct: 116 ILVNNAG 122
>NP_056325
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ILVKNAG 8
           ILV NAG
Sbjct: 138 ILVNNAG 144
>NP_115925
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QILVKNAGT 9
           Q+L +N GT
Sbjct: 460 QLLCQNGGT 468
>NP_065880
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QILVKNAG 8
           Q+LV+N G
Sbjct: 834 QLLVRNLG 841
>NP_001129392
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QILVKNAG 8
           Q+LV+N G
Sbjct: 834 QLLVRNLG 841
>NP_001193486
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QILVKNAG 8
           Q+LV+N G
Sbjct: 797 QLLVRNLG 804
>NP_620140
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ILVKNAG 8
           ILVKN G
Sbjct: 154 ILVKNRG 160
>XP_005259981
          Length = 2269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    QILVKNAGT 9
            QIL++N  T
Sbjct: 1837 QILIRNRST 1845
>XP_005256653
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ILVKNAG 8
           ILV NAG
Sbjct: 123 ILVNNAG 129
>XP_005256652
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ILVKNAG 8
           ILV NAG
Sbjct: 185 ILVNNAG 191
>XP_006717367
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QILVKNAGT 9
           Q+L +N GT
Sbjct: 494 QLLCQNGGT 502
>XP_005251580
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QILVKNAG 8
           Q+LV+N G
Sbjct: 833 QLLVRNLG 840
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.130    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 435,779
Number of extensions: 763
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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