Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002871                                                              18    1482
XP_005265416                                                           18    1482
XP_005265415                                                           18    1482
XP_005265414                                                           18    1482
XP_005265412                                                           18    1482
NP_004324                                                              18    1935
XP_005250102                                                           18    1935
NP_001243125                                                           17    4312
NP_001645                                                              17    4312
XP_006724592                                                           17    4312
NP_075266                                                              16    7355
NP_004449                                                              16    7355
XP_006724698                                                           16    7355
XP_005262167                                                           16    7355
XP_005262166                                                           16    7355
XP_005262165                                                           16    7355
XP_006723933                                                           16    7355
XP_005260589                                                           16    7355
NP_056093                                                              15    9605
XP_005266932                                                           15    9605
XP_006715469                                                           15    9605
XP_005266931                                                           15    9605



>NP_002871
          Length = 648

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QILTSIELL 9
           QIL+SIELL
Sbjct: 601 QILSSIELL 609





>XP_005265416
          Length = 534

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QILTSIELL 9
           QIL+SIELL
Sbjct: 487 QILSSIELL 495





>XP_005265415
          Length = 567

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QILTSIELL 9
           QIL+SIELL
Sbjct: 520 QILSSIELL 528





>XP_005265414
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QILTSIELL 9
           QIL+SIELL
Sbjct: 568 QILSSIELL 576





>XP_005265412
          Length = 648

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QILTSIELL 9
           QIL+SIELL
Sbjct: 601 QILSSIELL 609





>NP_004324
          Length = 766

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QILTSIELL 9
           QIL SIELL
Sbjct: 709 QILASIELL 717





>XP_005250102
          Length = 767

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QILTSIELL 9
           QIL SIELL
Sbjct: 709 QILASIELL 717





>NP_001243125
          Length = 609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QILTSIELL 9
           QIL +IELL
Sbjct: 565 QILATIELL 573





>NP_001645
          Length = 606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QILTSIELL 9
           QIL +IELL
Sbjct: 562 QILATIELL 570





>XP_006724592
          Length = 611

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QILTSIELL 9
           QIL +IELL
Sbjct: 567 QILATIELL 575





>NP_075266
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 201 LITSVELL 208





>NP_004449
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 160 LITSVELL 167





>XP_006724698
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 160 LITSVELL 167





>XP_005262167
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 160 LITSVELL 167





>XP_005262166
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 201 LITSVELL 208





>XP_005262165
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           ++TS+ELL
Sbjct: 201 LITSVELL 208





>XP_006723933
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  ILTSIELL 9
          ILTS ELL
Sbjct: 8  ILTSCELL 15





>XP_005260589
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  ILTSIELL 9
          ILTS ELL
Sbjct: 8  ILTSCELL 15





>NP_056093
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           +LT++ELL
Sbjct: 687 LLTAVELL 694





>XP_005266932
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           +LT++ELL
Sbjct: 448 LLTAVELL 455





>XP_006715469
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           +LT++ELL
Sbjct: 675 LLTAVELL 682





>XP_005266931
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILTSIELL 9
           +LT++ELL
Sbjct: 723 LLTAVELL 730





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.143    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,364
Number of extensions: 628
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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