Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1482
XP_005262424                                                           18    1482
NP_003882                                                              17    3301
NP_001243063                                                           17    3301
NP_006527                                                              17    3301
NP_001106849                                                           17    4312
NP_060663                                                              17    4312
NP_001103132                                                           17    4312
NP_055861                                                              16    5631
XP_005272230                                                           16    5631
XP_005272229                                                           16    5631
XP_005272228                                                           16    5631
NP_002277                                                              16    5631
NP_002153                                                              16    7355
NP_006176                                                              16    7355
NP_932348                                                              16    7355
NP_001273490                                                           16    7355
XP_005256402                                                           16    7355
XP_006722342                                                           16    7355
XP_006718633                                                           16    7355
XP_006718632                                                           16    7355
XP_006718631                                                           16    7355
XP_006718630                                                           16    7355
XP_006718629                                                           16    7355
XP_006718628                                                           16    7355
XP_006718627                                                           16    7355
XP_006718626                                                           16    7355
XP_006718625                                                           16    7355
NP_003288                                                              15    9605
XP_006719648                                                           15    9605
XP_006719647                                                           15    9605
XP_005269190                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QILNATVTR 9
           Q LNATVTR
Sbjct: 833 QRLNATVTR 841
>XP_005262424
          Length = 2875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QILNATVTR 9
           Q LNATVTR
Sbjct: 628 QRLNATVTR 636
>NP_003882
          Length = 400

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QILNATVT 8
           Q+LN TVT
Sbjct: 329 QVLNVTVT 336
>NP_001243063
          Length = 422

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QILNATVT 8
           Q+LN TVT
Sbjct: 351 QVLNVTVT 358
>NP_006527
          Length = 943

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILNATVT 8
           ILNATVT
Sbjct: 635 ILNATVT 641
>NP_001106849
          Length = 1328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QILNATVTR 9
           Q+LN  VTR
Sbjct: 443 QVLNRVVTR 451
>NP_060663
          Length = 1268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QILNATVTR 9
           Q+LN  VTR
Sbjct: 443 QVLNRVVTR 451
>NP_001103132
          Length = 4284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            ++LNATV R
Sbjct: 3857 RVLNATVQR 3865
>NP_055861
          Length = 2677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QILNATVTR 9
            Q LN T+TR
Sbjct: 2406 QRLNVTITR 2414
>XP_005272230
          Length = 2706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QILNATVTR 9
            Q LN T+TR
Sbjct: 2406 QRLNVTITR 2414
>XP_005272229
          Length = 2706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QILNATVTR 9
            Q LN T+TR
Sbjct: 2406 QRLNVTITR 2414
>XP_005272228
          Length = 2706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QILNATVTR 9
            Q LN T+TR
Sbjct: 2406 QRLNVTITR 2414
>NP_002277
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   QILNATVT 8
           Q LNATVT
Sbjct: 340 QQLNATVT 347
>NP_002153
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QILNATV 7
           Q+LNATV
Sbjct: 261 QMLNATV 267
>NP_006176
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>NP_932348
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QILNATVTR 9
           Q+LN  VTR
Sbjct: 668 QLLNLLVTR 676
>NP_001273490
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1799 QIINITMTK 1807
>XP_005256402
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QILNATVTR 9
           Q+LN  VTR
Sbjct: 668 QLLNLLVTR 676
>XP_006722342
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QILNATVTR 9
           Q+LN  VTR
Sbjct: 679 QLLNLLVTR 687
>XP_006718633
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1799 QIINITMTK 1807
>XP_006718632
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718631
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718630
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718629
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718628
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718627
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718626
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>XP_006718625
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QILNATVTR 9
            QI+N T+T+
Sbjct: 1813 QIINITMTK 1821
>NP_003288
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QILNATVT 8
           +++NAT+T
Sbjct: 558 RLMNATIT 565
>XP_006719648
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QILNATVT 8
           +++NAT+T
Sbjct: 381 RLMNATIT 388
>XP_006719647
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QILNATVT 8
           +++NAT+T
Sbjct: 512 RLMNATIT 519
>XP_005269190
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QILNATVT 8
           +++NAT+T
Sbjct: 553 RLMNATIT 560
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.126    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 298,440
Number of extensions: 362
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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