Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              20     299
NP_001262                                                              20     299
XP_005271924                                                           20     299
XP_005271923                                                           20     299
NP_000115                                                              18    1482
NP_624358                                                              17    2528
NP_057404                                                              17    2528
XP_006718305                                                           17    2528
XP_006718304                                                           17    2528
XP_006718303                                                           17    2528
XP_005253007                                                           17    2528
NP_003963                                                              17    4312
XP_005270323                                                           17    4312
XP_005270322                                                           17    4312
NP_078964                                                              16    5631
XP_005252650                                                           16    5631
XP_006717569                                                           16    5631
XP_006717568                                                           16    5631
XP_006717567                                                           16    5631
NP_001128680                                                           16    7355
NP_055772                                                              16    7355
NP_001269804                                                           16    7355
NP_001269803                                                           16    7355
NP_003060                                                              16    7355
XP_006724845                                                           16    7355
XP_005262519                                                           16    7355
XP_005262518                                                           16    7355
XP_006718539                                                           16    7355
XP_005273905                                                           16    7355
XP_005250902                                                           16    7355
XP_005250901                                                           16    7355
XP_005250900                                                           16    7355
XP_005250899                                                           16    7355
XP_005250898                                                           16    7355
XP_005250897                                                           16    7355
XP_005250896                                                           16    7355
XP_005250895                                                           16    7355
NP_004461                                                              16    7355
NP_476433                                                              16    7355
NP_001034782                                                           15    9605
NP_001367                                                              15    9605
NP_006428                                                              15    9605
NP_003244                                                              15    9605
NP_002425                                                              15    9605
NP_077734                                                              15    9605
NP_001015052                                                           15    9605
XP_005261097                                                           15    9605
XP_005261096                                                           15    9605
XP_005261095                                                           15    9605
XP_005261094                                                           15    9605
XP_005260927                                                           15    9605
XP_006723726                                                           15    9605
XP_005260924                                                           15    9605
XP_005260923                                                           15    9605
XP_005245325                                                           15    9605
XP_005245324                                                           15    9605
NP_443097                                                              15    9605
>NP_001261
          Length = 1710

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QIGQKKQVN 9
           +IGQKKQVN
Sbjct: 900 RIGQKKQVN 908
>NP_001262
          Length = 1828

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QIGQKKQVN 9
           +IGQKKQVN
Sbjct: 903 RIGQKKQVN 911
>XP_005271924
          Length = 1710

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QIGQKKQVN 9
           +IGQKKQVN
Sbjct: 900 RIGQKKQVN 908
>XP_005271923
          Length = 1798

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QIGQKKQVN 9
           +IGQKKQVN
Sbjct: 900 RIGQKKQVN 908
>NP_000115
          Length = 1493

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   QIGQKKQV 8
           +IGQKKQV
Sbjct: 950 RIGQKKQV 957
>NP_624358
          Length = 1726

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1392 QLSEKKQIN 1400
>NP_057404
          Length = 1800

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1392 QLSEKKQIN 1400
>XP_006718305
          Length = 1743

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1409 QLSEKKQIN 1417
>XP_006718304
          Length = 1753

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1345 QLSEKKQIN 1353
>XP_006718303
          Length = 1792

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1384 QLSEKKQIN 1392
>XP_005253007
          Length = 1817

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            Q+ +KKQ+N
Sbjct: 1409 QLSEKKQIN 1417
>NP_003963
          Length = 1849

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            +IGQK+ VN
Sbjct: 1742 RIGQKRVVN 1750
>XP_005270323
          Length = 1519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            +IGQK+ VN
Sbjct: 1412 RIGQKRVVN 1420
>XP_005270322
          Length = 1646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QIGQKKQVN 9
            +IGQK+ VN
Sbjct: 1539 RIGQKRVVN 1547
>NP_078964
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QIGQKKQVN 9
           Q+ +KKQ+N
Sbjct: 218 QMQEKKQIN 226
>XP_005252650
          Length = 692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QIGQKKQVN 9
           Q+ +KKQ+N
Sbjct: 218 QMQEKKQIN 226
>XP_006717569
          Length = 1278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QIGQKKQVN 9
           Q+ +KKQ+N
Sbjct: 804 QMQEKKQIN 812
>XP_006717568
          Length = 1314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QIGQKKQVN 9
           Q+ +KKQ+N
Sbjct: 840 QMQEKKQIN 848
>XP_006717567
          Length = 1385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QIGQKKQVN 9
           Q+ +KKQ+N
Sbjct: 911 QMQEKKQIN 919
>NP_001128680
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QIGQKKQVN 9
          QIG KK+V+
Sbjct: 32 QIGVKKRVD 40
>NP_055772
          Length = 1198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 678 VGQEKQID 685
>NP_001269804
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 598 RIGQKKPV 605
>NP_001269803
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 610 RIGQKKPV 617
>NP_003060
          Length = 1054

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 610 RIGQKKPV 617
>XP_006724845
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 598 RIGQKKPV 605
>XP_005262519
          Length = 1048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 610 RIGQKKPV 617
>XP_005262518
          Length = 1054

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QIGQKKQV 8
           +IGQKK V
Sbjct: 610 RIGQKKPV 617
>XP_006718539
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QIGQKKQVN 9
          QIG KK+V+
Sbjct: 32 QIGVKKRVD 40
>XP_005273905
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QIGQKKQVN 9
          QIG KK+V+
Sbjct: 32 QIGVKKRVD 40
>XP_005250902
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 270 VGQEKQID 277
>XP_005250901
          Length = 900

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 362 VGQEKQID 369
>XP_005250900
          Length = 1048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 510 VGQEKQID 517
>XP_005250899
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 680 VGQEKQID 687
>XP_005250898
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 706 VGQEKQID 713
>XP_005250897
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 706 VGQEKQID 713
>XP_005250896
          Length = 1278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 758 VGQEKQID 765
>XP_005250895
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +GQ+KQ++
Sbjct: 758 VGQEKQID 765
>NP_004461
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QIGQKKQVN 9
          QIG KK+V+
Sbjct: 32 QIGVKKRVD 40
>NP_476433
          Length = 142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QIGQKKQVN 9
          QIG KK+V+
Sbjct: 32 QIGVKKRVD 40
>NP_001034782
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QIGQKKQV 8
          Q+G KK+V
Sbjct: 51 QVGGKKEV 58
>NP_001367
          Length = 4646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    GQKKQVN 9
            G+KKQ N
Sbjct: 4440 GKKKQTN 4446
>NP_006428
          Length = 1724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   IGQKKQVN 9
           +G+K++VN
Sbjct: 906 VGEKQKVN 913
>NP_003244
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QIGQKKQV 8
            Q G+KK+V
Sbjct: 1252 QTGEKKEV 1259
>NP_002425
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QIGQKKQ 7
          ++GQKKQ
Sbjct: 17 RMGQKKQ 23
>NP_077734
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QIGQKKQV 8
           ++G+KK+V
Sbjct: 113 KVGEKKEV 120
>NP_001015052
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QIGQKKQ 7
          ++GQKKQ
Sbjct: 12 RMGQKKQ 18
>XP_005261097
          Length = 1452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QIGQKKQV 8
            Q G+KK+V
Sbjct: 1252 QTGEKKEV 1259
>XP_005261096
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QIGQKKQV 8
            Q G+KK+V
Sbjct: 1252 QTGEKKEV 1259
>XP_005261095
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QIGQKKQV 8
            Q G+KK+V
Sbjct: 1252 QTGEKKEV 1259
>XP_005261094
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    QIGQKKQV 8
            Q G+KK+V
Sbjct: 1252 QTGEKKEV 1259
>XP_005260927
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GQKKQVN 9
          G+KK+VN
Sbjct: 36 GRKKKVN 42
>XP_006723726
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GQKKQVN 9
          G+KK+VN
Sbjct: 36 GRKKKVN 42
>XP_005260924
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GQKKQVN 9
          G+KK+VN
Sbjct: 36 GRKKKVN 42
>XP_005260923
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GQKKQVN 9
          G+KK+VN
Sbjct: 36 GRKKKVN 42
>XP_005245325
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   QIGQKKQV 8
           ++G+KK+V
Sbjct: 113 KVGEKKEV 120
>XP_005245324
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  QIGQKKQV 8
          ++G+KK+V
Sbjct: 76 KVGEKKEV 83
>NP_443097
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GQKKQVN 9
          G+KK+VN
Sbjct: 36 GRKKKVN 42
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.124    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 587,213
Number of extensions: 769
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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