Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              17    4312
NP_001263689                                                           17    4312
NP_001119584                                                           17    4312
NP_001119586                                                           17    4312
NP_001263625                                                           17    4312
NP_001119590                                                           17    4312
NP_001263690                                                           17    4312
NP_001119585                                                           17    4312
NP_001263624                                                           17    4312
NP_001119588                                                           17    4312
NP_001119587                                                           17    4312
NP_001119589                                                           17    4312
NP_001263627                                                           17    4312
NP_001263628                                                           17    4312
NP_001263626                                                           17    4312
NP_660213                                                              16    5631
NP_004283                                                              16    5631
NP_065145                                                              16    7355
NP_060487                                                              16    7355
XP_005269994                                                           16    7355
NP_001265853                                                           15    9605
NP_001244073                                                           15    9605
NP_001244074                                                           15    9605
NP_001121646                                                           15    9605
NP_689651                                                              15    9605
NP_085911                                                              15    9605
NP_004390                                                              15    9605
XP_006719115                                                           15    9605
XP_005253390                                                           15    9605
XP_006719114                                                           15    9605
XP_006719113                                                           15    9605
XP_006719112                                                           15    9605
XP_006719111                                                           15    9605
XP_006719110                                                           15    9605
XP_006719109                                                           15    9605
XP_006719108                                                           15    9605
XP_006719107                                                           15    9605
XP_005253388                                                           15    9605
XP_006719106                                                           15    9605
XP_006719105                                                           15    9605
XP_006719104                                                           15    9605
XP_006714366                                                           15    9605
XP_006714365                                                           15    9605
NP_003351                                                              15    9605
>NP_000537
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 192 QHLIRVE 198
>NP_001263689
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 153 QHLIRVE 159
>NP_001119584
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 192 QHLIRVE 198
>NP_001119586
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 192 QHLIRVE 198
>NP_001263625
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 153 QHLIRVE 159
>NP_001119590
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 153 QHLIRVE 159
>NP_001263690
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 153 QHLIRVE 159
>NP_001119585
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 192 QHLIRVE 198
>NP_001263624
          Length = 307

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           QHLIRV+
Sbjct: 153 QHLIRVE 159
>NP_001119588
          Length = 209

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 60 QHLIRVE 66
>NP_001119587
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 60 QHLIRVE 66
>NP_001119589
          Length = 214

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 60 QHLIRVE 66
>NP_001263627
          Length = 182

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 33 QHLIRVE 39
>NP_001263628
          Length = 187

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 33 QHLIRVE 39
>NP_001263626
          Length = 234

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QHLIRVK 7
          QHLIRV+
Sbjct: 33 QHLIRVE 39
>NP_660213
          Length = 161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QHLIRVK 7
           +HLIR+K
Sbjct: 114 KHLIRIK 120
>NP_004283
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QHLIRVKF 8
           QHL+RV +
Sbjct: 625 QHLLRVAY 632
>NP_065145
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QHLIRVKFA 9
          +HL  +KFA
Sbjct: 6  KHLFNLKFA 14
>NP_060487
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   HLIRVKFA 9
           H+I+VK+A
Sbjct: 388 HVIKVKWA 395
>XP_005269994
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   HLIRVKFA 9
           H+I+VK+A
Sbjct: 388 HVIKVKWA 395
>NP_001265853
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   HLIRVK 7
           HL+RVK
Sbjct: 193 HLLRVK 198
>NP_001244073
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>NP_001244074
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 122 QHRVQLKYA 130
>NP_001121646
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLIRVKFA 9
           HL+ VK+A
Sbjct: 149 HLLGVKYA 156
>NP_689651
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>NP_085911
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>NP_004390
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>XP_006719115
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_005253390
          Length = 942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719114
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719113
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719112
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 122 QHRVQLKYA 130
>XP_006719111
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 122 QHRVQLKYA 130
>XP_006719110
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>XP_006719109
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>XP_006719108
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>XP_006719107
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 148 QHRVQLKYA 156
>XP_005253388
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719106
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719105
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006719104
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QHLIRVKFA 9
           QH +++K+A
Sbjct: 184 QHRVQLKYA 192
>XP_006714366
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLIRVKFA 9
           HL+ VK+A
Sbjct: 149 HLLGVKYA 156
>XP_006714365
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLIRVKFA 9
           HL+ VK+A
Sbjct: 149 HLLGVKYA 156
>NP_003351
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLIRVKFA 9
           HL+ VK+A
Sbjct: 149 HLLGVKYA 156
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.148    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 498,822
Number of extensions: 873
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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