Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001092908                                                           17    4312
NP_001092907                                                           17    4312
NP_919306                                                              17    4312
NP_689914                                                              16    5631
NP_001009984                                                           16    5631
NP_115551                                                              16    5631
NP_001271359                                                           16    5631
NP_001271360                                                           16    5631
XP_005260744                                                           16    5631
XP_005260743                                                           16    5631
XP_006723620                                                           16    5631
XP_006723619                                                           16    5631
XP_005260741                                                           16    5631
XP_006715914                                                           16    5631
NP_006097                                                              16    7355
NP_001269028                                                           16    7355
NP_001181973                                                           16    7355
NP_001269030                                                           16    7355
NP_001123617                                                           16    7355
NP_001269026                                                           16    7355
NP_001269029                                                           16    7355
NP_001269027                                                           16    7355
NP_891550                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_596870                                                              16    7355
NP_001243779                                                           16    7355
NP_149985                                                              16    7355
NP_596869                                                              16    7355
NP_659483                                                              16    7355
XP_005271440                                                           16    7355
XP_005271438                                                           16    7355
XP_005271437                                                           16    7355
XP_005271435                                                           16    7355
XP_005265386                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
NP_056471                                                              16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_000375                                                              15    9605
NP_001124463                                                           15    9605
NP_006380                                                              15    9605
NP_009041                                                              15    9605
NP_689612                                                              15    9605
NP_653191                                                              15    9605
NP_006355                                                              15    9605
NP_060899                                                              15    9605
XP_006725524                                                           15    9605
XP_006725523                                                           15    9605
XP_005276828                                                           15    9605
XP_006726279                                                           15    9605
XP_005268084                                                           15    9605
XP_005267319                                                           15    9605
XP_005271451                                                           15    9605
XP_005271450                                                           15    9605
XP_005271449                                                           15    9605
XP_005271447                                                           15    9605
XP_006714722                                                           15    9605
XP_006714721                                                           15    9605
XP_005262797                                                           15    9605
XP_005262794                                                           15    9605
>NP_001092908
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR+SSFL
Sbjct: 354 FRLSSFL 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR++SFL
Sbjct: 578 FRLNSFL 584
>NP_001092907
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR+SSFL
Sbjct: 354 FRLSSFL 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR++SFL
Sbjct: 578 FRLNSFL 584
>NP_919306
          Length = 623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR+SSFL
Sbjct: 353 FRLSSFL 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRISSFL 9
           FR++SFL
Sbjct: 577 FRLNSFL 583
>NP_689914
          Length = 5058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   HFRISSF 8
           HFR+S F
Sbjct: 94  HFRLSRF 100
>NP_001009984
          Length = 1177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 710 QHFAISS 716
>NP_115551
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QHFRISSFL 9
           +HFRIS  L
Sbjct: 369 KHFRISKAL 377
>NP_001271359
          Length = 499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QHFRISSFL 9
           +HFRIS  L
Sbjct: 350 KHFRISKAL 358
>NP_001271360
          Length = 328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QHFRISSFL 9
           +HFRIS  L
Sbjct: 179 KHFRISKAL 187
>XP_005260744
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 125 QHFAISS 131
>XP_005260743
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 710 QHFAISS 716
>XP_006723620
          Length = 874

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 710 QHFAISS 716
>XP_006723619
          Length = 1151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 684 QHFAISS 690
>XP_005260741
          Length = 1176

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QHFRISS 7
           QHF ISS
Sbjct: 709 QHFAISS 715
>XP_006715914
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF +S+FL
Sbjct: 302 HFSLSNFL 309
>NP_006097
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001269028
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001181973
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001269030
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001123617
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001269026
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001269029
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_001269027
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>NP_891550
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   HFRISSF 8
           H+R+S+F
Sbjct: 99  HYRLSAF 105
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1197 QEFHISSF 1204
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1197 QEFHISSF 1204
>NP_596870
          Length = 5604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1243 QEFHISSF 1250
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1243 QEFHISSF 1250
>NP_149985
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           H RI SFL
Sbjct: 521 HSRIGSFL 528
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1243 QEFHISSF 1250
>NP_659483
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  HFRISS 7
          HFR+SS
Sbjct: 48 HFRLSS 53
>XP_005271440
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>XP_005271438
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>XP_005271437
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>XP_005271435
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QHFRISSF 8
           QH R SSF
Sbjct: 158 QHLRQSSF 165
>XP_005265386
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   HFRISSF 8
           H+R+S+F
Sbjct: 99  HYRLSAF 105
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1244 QEFHISSF 1251
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1244 QEFHISSF 1251
>NP_056471
          Length = 1882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   HFRISSF 8
           HFR S+F
Sbjct: 835 HFRCSTF 841
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1243 QEFHISSF 1250
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    QHFRISSF 8
            Q F ISSF
Sbjct: 1197 QEFHISSF 1204
>NP_000375
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    FRISSF 8
            FR+SSF
Sbjct: 1490 FRVSSF 1495
>NP_001124463
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>NP_006380
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>NP_009041
          Length = 2627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    HFRISSFL 9
            +FR SSFL
Sbjct: 1028 YFRDSSFL 1035
>NP_689612
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           HF + SFL
Sbjct: 98  HFLLKSFL 105
>NP_653191
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  HFRISSFL 9
          H RI SFL
Sbjct: 52 HVRIVSFL 59
>NP_006355
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           H R SSFL
Sbjct: 583 HLRRSSFL 590
>NP_060899
          Length = 2624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_006725524
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_006725523
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_005276828
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_006726279
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_005268084
          Length = 2627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    HFRISSFL 9
            +FR SSFL
Sbjct: 1028 YFRDSSFL 1035
>XP_005267319
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           H R SSFL
Sbjct: 607 HLRRSSFL 614
>XP_005271451
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>XP_005271450
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>XP_005271449
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>XP_005271447
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HFRISSFL 9
           HF+ISS L
Sbjct: 135 HFQISSQL 142
>XP_006714722
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_006714721
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    HFRISS 7
            HF+ISS
Sbjct: 1383 HFKISS 1388
>XP_005262797
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           HF + SFL
Sbjct: 98  HFLLKSFL 105
>XP_005262794
          Length = 130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   HFRISSFL 9
           HF + SFL
Sbjct: 98  HFLLKSFL 105
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.146    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 489,546
Number of extensions: 629
Number of successful extensions: 65
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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