Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     509
NP_444254                                                              20     509
NP_444253                                                              20     509
NP_444255                                                              20     509
XP_005247551                                                           20     509
XP_005247550                                                           20     509
XP_006713712                                                           20     509
XP_005247549                                                           20     509
NP_059509                                                              17    2528
NP_116251                                                              17    3301
NP_002197                                                              17    4312
NP_001138468                                                           17    4312
NP_001138469                                                           17    4312
NP_056957                                                              17    4312
XP_005268907                                                           17    4312
XP_005268906                                                           17    4312
XP_005268905                                                           17    4312
XP_005268904                                                           17    4312
XP_005268903                                                           17    4312
XP_005268902                                                           17    4312
XP_005268901                                                           17    4312
XP_005268899                                                           17    4312
XP_005268898                                                           17    4312
XP_005268897                                                           17    4312
XP_005268896                                                           17    4312
XP_005265249                                                           17    4312
XP_006713247                                                           17    4312
XP_006713246                                                           17    4312
XP_005265248                                                           17    4312
NP_828848                                                              17    4312
NP_055626                                                              16    5631
NP_001091995                                                           16    5631
NP_065978                                                              16    5631
NP_060674                                                              16    5631
XP_005266401                                                           16    5631
XP_005266400                                                           16    5631
XP_006717405                                                           16    5631
XP_006717404                                                           16    5631
XP_006717403                                                           16    5631
XP_005263469                                                           16    5631
XP_005263468                                                           16    5631
NP_001273615                                                           16    5631
NP_001257545                                                           16    7355
NP_002754                                                              16    7355
NP_059344                                                              16    7355
NP_006331                                                              16    7355
NP_059345                                                              16    7355
XP_005257005                                                           16    7355
XP_006721701                                                           16    7355
XP_006721700                                                           16    7355
XP_005257002                                                           16    7355
XP_005257001                                                           16    7355
XP_006721699                                                           16    7355
XP_006721698                                                           16    7355
XP_005257000                                                           16    7355
XP_006711518                                                           16    7355
XP_005273252                                                           16    7355
XP_005273253                                                           16    7355
XP_005273251                                                           16    7355
NP_001138360                                                           16    7355
NP_003918                                                              15    9605
NP_001180438                                                           15    9605
NP_001268383                                                           15    9605
NP_001268382                                                           15    9605
NP_060205                                                              15    9605
NP_001171019                                                           15    9605
NP_001171020                                                           15    9605
NP_001236                                                              15    9605
NP_942143                                                              15    9605
XP_005264473                                                           15    9605
>NP_444256
          Length = 1794

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1025 QGTAPAFKQ 1033
>NP_444254
          Length = 1845

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1025 QGTAPAFKQ 1033
>NP_444253
          Length = 1914

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1094 QGTAPAFKQ 1102
>NP_444255
          Length = 1863

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1094 QGTAPAFKQ 1102
>XP_005247551
          Length = 1855

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1035 QGTAPAFKQ 1043
>XP_005247550
          Length = 1856

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1104 QGTAPAFKQ 1112
>XP_006713712
          Length = 1923

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1104 QGTAPAFKQ 1112
>XP_005247549
          Length = 1924

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QGTASAFKQ 9
            QGTA AFKQ
Sbjct: 1104 QGTAPAFKQ 1112
>NP_059509
          Length = 655

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QGTASAFKQ 9
           QGTASA  Q
Sbjct: 361 QGTASALSQ 369
>NP_116251
          Length = 642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QGTASAFKQ 9
           QG  +AFKQ
Sbjct: 419 QGVVAAFKQ 427
>NP_002197
          Length = 1137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138468
          Length = 1141

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>NP_001138469
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 102 QGTAAAF 108
>NP_056957
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QGTASAFKQ 9
          QG A AF+Q
Sbjct: 73 QGAAEAFQQ 81
>XP_005268907
          Length = 979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268906
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268905
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268904
          Length = 1023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 41 QGTAAAF 47
>XP_005268903
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268902
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268901
          Length = 1068

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  QGTASAF 7
          QGTA+AF
Sbjct: 86 QGTAAAF 92
>XP_005268899
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268898
          Length = 1162

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268897
          Length = 1175

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005268896
          Length = 1181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QGTASAF 7
           QGTA+AF
Sbjct: 199 QGTAAAF 205
>XP_005265249
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QGTASAFKQ 9
          QG A AF+Q
Sbjct: 73 QGAAEAFQQ 81
>XP_006713247
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QGTASAFKQ 9
          QG A AF+Q
Sbjct: 73 QGAAEAFQQ 81
>XP_006713246
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QGTASAFKQ 9
          QG A AF+Q
Sbjct: 73 QGAAEAFQQ 81
>XP_005265248
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QGTASAFKQ 9
          QG A AF+Q
Sbjct: 73 QGAAEAFQQ 81
>NP_828848
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GTASAFK 8
           GTASAF+
Sbjct: 202 GTASAFR 208
>NP_055626
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>NP_001091995
          Length = 683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTASAFKQ 9
           GT SAFK+
Sbjct: 611 GTNSAFKE 618
>NP_065978
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTASAFK 8
           GTAS FK
Sbjct: 211 GTASTFK 217
>NP_060674
          Length = 682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTASAFKQ 9
           GT SAFK+
Sbjct: 610 GTNSAFKE 617
>XP_005266401
          Length = 635

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTASAFKQ 9
           GT SAFK+
Sbjct: 563 GTNSAFKE 570
>XP_005266400
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTASAFKQ 9
           GT SAFK+
Sbjct: 605 GTNSAFKE 612
>XP_006717405
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>XP_006717404
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>XP_006717403
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>XP_005263469
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>XP_005263468
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QGTASAFKQ 9
           QGTA  F Q
Sbjct: 914 QGTAGLFSQ 922
>NP_001273615
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTASAFKQ 9
           GT SAFK+
Sbjct: 562 GTNSAFKE 569
>NP_001257545
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>NP_002754
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>NP_059344
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 482 TASGFKQ 488
>NP_006331
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 482 TASGFKQ 488
>NP_059345
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 482 TASGFKQ 488
>XP_005257005
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 483 TASGFKQ 489
>XP_006721701
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 477 TASGFKQ 483
>XP_006721700
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 483 TASGFKQ 489
>XP_005257002
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 515 TASGFKQ 521
>XP_005257001
          Length = 554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 515 TASGFKQ 521
>XP_006721699
          Length = 554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 516 TASGFKQ 522
>XP_006721698
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 516 TASGFKQ 522
>XP_005257000
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 515 TASGFKQ 521
>XP_006711518
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273252
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273253
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>XP_005273251
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GTASAF 7
          GTASAF
Sbjct: 28 GTASAF 33
>NP_001138360
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 482 TASGFKQ 488
>NP_003918
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 248 TASIFKQ 254
>NP_001180438
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QGTASAFKQ 9
           QG+A AF++
Sbjct: 528 QGSAKAFQR 536
>NP_001268383
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TASAFKQ 9
          TAS FKQ
Sbjct: 72 TASIFKQ 78
>NP_001268382
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TASAFKQ 9
           TAS FKQ
Sbjct: 104 TASIFKQ 110
>NP_060205
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QGTASAFKQ 9
           QG+A AF++
Sbjct: 578 QGSAKAFQR 586
>NP_001171019
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGTASAFK 8
           QG ++AFK
Sbjct: 258 QGNSAAFK 265
>NP_001171020
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGTASAFK 8
           QG ++AFK
Sbjct: 236 QGNSAAFK 243
>NP_001236
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGTASAFK 8
           QG ++AFK
Sbjct: 247 QGNSAAFK 254
>NP_942143
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QGTASAFK 8
           QG ++AFK
Sbjct: 247 QGNSAAFK 254
>XP_005264473
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QGTASAFKQ 9
           QG+A AF++
Sbjct: 537 QGSAKAFQR 545
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.112    0.286 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 392,711
Number of extensions: 539
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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