Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              19     869
NP_002935                                                              17    3301
XP_006715611                                                           17    3301
NP_848612                                                              16    7355
XP_006725381                                                           16    7355
XP_006725380                                                           16    7355
XP_005257295                                                           16    7355
XP_006721894                                                           16    7355
XP_005251848                                                           16    7355
XP_005251847                                                           16    7355
XP_005251846                                                           16    7355
NP_001926                                                              15    9605
NP_056011                                                              15    9605
NP_001124479                                                           15    9605
NP_001129157                                                           15    9605
NP_996844                                                              15    9605
XP_005254439                                                           15    9605
XP_006720568                                                           15    9605
XP_005254438                                                           15    9605
XP_005262928                                                           15    9605
XP_005262927                                                           15    9605
XP_005262926                                                           15    9605
XP_005246428                                                           15    9605
NP_002335                                                              15    9605
>NP_004295
          Length = 1620

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QFILLELMA 9
            +FILLELMA
Sbjct: 1192 RFILLELMA 1200
>NP_002935
          Length = 2347

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    QFILLELM 8
            Q+I+LELM
Sbjct: 2022 QYIILELM 2029
>XP_006715611
          Length = 2342

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    QFILLELM 8
            Q+I+LELM
Sbjct: 2017 QYIILELM 2024
>NP_848612
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006725381
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006725380
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_005257295
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006721894
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_005251848
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QFILLELMA 9
          QF+ LEL A
Sbjct: 53 QFLYLELQA 61
>XP_005251847
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QFILLELMA 9
          QF+ LEL A
Sbjct: 53 QFLYLELQA 61
>XP_005251846
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QFILLELMA 9
          QF+ LEL A
Sbjct: 53 QFLYLELQA 61
>NP_001926
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QFILLE 6
           QFILLE
Sbjct: 112 QFILLE 117
>NP_056011
          Length = 1609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QFILLELM 8
           Q+IL+E M
Sbjct: 894 QYILMEFM 901
>NP_001124479
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QFILLELM 8
           Q+IL+E M
Sbjct: 895 QYILMEFM 902
>NP_001129157
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 456 RLILLELMS 464
>NP_996844
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 525 RLILLELMS 533
>XP_005254439
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 197 RLILLELMS 205
>XP_006720568
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 493 RLILLELMS 501
>XP_005254438
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 541 RLILLELMS 549
>XP_005262928
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QFILLELM 8
           Q+IL+E M
Sbjct: 250 QYILMEFM 257
>XP_005262927
          Length = 1526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QFILLELM 8
           Q+IL+E M
Sbjct: 811 QYILMEFM 818
>XP_005262926
          Length = 1609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QFILLELM 8
           Q+IL+E M
Sbjct: 895 QYILMEFM 902
>XP_005246428
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QFILLE 6
           QFILLE
Sbjct: 111 QFILLE 116
>NP_002335
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QFILLELMA 9
           + ILLELM+
Sbjct: 586 RLILLELMS 594
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.156    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,157
Number of extensions: 407
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package