Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
NP_001271226                                                           19     869
NP_001271227                                                           19     869
XP_005254507                                                           19     869
XP_005254506                                                           19     869
XP_005254505                                                           19     869
XP_006720635                                                           19     869
XP_006720634                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_004564                                                              19     869
NP_001271279                                                           18    1135
NP_001025190                                                           18    1135
NP_689995                                                              18    1135
NP_079029                                                              17    2528
XP_006713366                                                           17    2528
XP_006712824                                                           17    2528
NP_055661                                                              17    4312
XP_005251177                                                           17    4312
NP_689823                                                              16    5631
NP_038476                                                              16    7355
NP_872589                                                              16    7355
XP_005264276                                                           16    7355
XP_005264275                                                           16    7355
NP_055962                                                              16    7355
NP_000490                                                              15    9605
NP_997192                                                              15    9605
NP_056040                                                              15    9605
NP_001229715                                                           15    9605
NP_001229716                                                           15    9605
NP_001229718                                                           15    9605
NP_001229717                                                           15    9605
NP_663718                                                              15    9605
NP_001510                                                              15    9605
NP_060009                                                              15    9605
NP_001193926                                                           15    9605
NP_689983                                                              15    9605
XP_006721125                                                           15    9605
XP_005254242                                                           15    9605
XP_006720186                                                           15    9605
XP_005267620                                                           15    9605
XP_006720185                                                           15    9605
XP_005267618                                                           15    9605
XP_006717380                                                           15    9605
XP_005251811                                                           15    9605
XP_005251810                                                           15    9605
XP_005251809                                                           15    9605
XP_005251808                                                           15    9605
XP_005251807                                                           15    9605
XP_005251805                                                           15    9605
XP_005251803                                                           15    9605
XP_006717050                                                           15    9605
XP_005251802                                                           15    9605
XP_006717049                                                           15    9605
XP_006717048                                                           15    9605
XP_006717047                                                           15    9605
XP_006717046                                                           15    9605
XP_006717045                                                           15    9605
XP_006714232                                                           15    9605
XP_005262940                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QEISSLV Y
Sbjct: 95  QEISSLVKY 103
>NP_001271226
          Length = 1181

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 540 EEMSSLVNY 548
>NP_001271227
          Length = 1170

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_005254507
          Length = 1070

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_005254506
          Length = 1123

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_005254505
          Length = 1124

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_006720635
          Length = 1125

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_006720634
          Length = 1184

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QEISSLV Y
Sbjct: 95  QEISSLVKY 103
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QEISSLV Y
Sbjct: 95  QEISSLVKY 103
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QEISSLV Y
Sbjct: 95  QEISSLVKY 103
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QEISSLV Y
Sbjct: 95  QEISSLVKY 103
>NP_004564
          Length = 1185

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+SSLVNY
Sbjct: 544 EEMSSLVNY 552
>NP_001271279
          Length = 345

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+S+LVNY
Sbjct: 152 EEVSNLVNY 160
>NP_001025190
          Length = 357

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+S+LVNY
Sbjct: 164 EEVSNLVNY 172
>NP_689995
          Length = 357

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QEISSLVNY 9
           +E+S+LVNY
Sbjct: 164 EEVSNLVNY 172
>NP_079029
          Length = 1316

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QEISSLVNY 9
          QE+ +L+NY
Sbjct: 4  QELKTLINY 12
>XP_006713366
          Length = 517

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           QE+S L+NY
Sbjct: 468 QELSCLLNY 476
>XP_006712824
          Length = 1056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QEISSLVNY 9
          QE+ +L+NY
Sbjct: 4  QELKTLINY 12
>NP_055661
          Length = 1159

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           +E+S ++NY
Sbjct: 772 EEVSRIINY 780
>XP_005251177
          Length = 1011

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           +E+S ++NY
Sbjct: 624 EEVSRIINY 632
>NP_689823
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSLVNY 9
           +SSL+NY
Sbjct: 424 LSSLINY 430
>NP_038476
          Length = 1556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QEISSLVNY 9
            Q +SS+V+Y
Sbjct: 1071 QSVSSVVHY 1079
>NP_872589
          Length = 1524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QEISSLVNY 9
            Q +SS+V+Y
Sbjct: 1039 QSVSSVVHY 1047
>XP_005264276
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EISSLVNY 9
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>XP_005264275
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EISSLVNY 9
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>NP_055962
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EISSLVNY 9
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>NP_000490
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QEISSLVN 8
           QE+ SLVN
Sbjct: 212 QELLSLVN 219
>NP_997192
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EISSLVNY 9
           EIS LV+Y
Sbjct: 467 EISPLVSY 474
>NP_056040
          Length = 3088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>NP_001229715
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 439 KKISSKINY 447
>NP_001229716
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 417 KKISSKINY 425
>NP_001229718
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 294 KKISSKINY 302
>NP_001229717
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 505 KKISSKINY 513
>NP_663718
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 328 KKISSKINY 336
>NP_001510
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 532 KKISSKINY 540
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEISSLVNY 9
           Q+IS +V Y
Sbjct: 958 QQISEIVGY 966
>NP_001193926
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEISSLVNY 9
           QEIS  ++Y
Sbjct: 141 QEISGYIDY 149
>NP_689983
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEISSLVNY 9
           QEIS  ++Y
Sbjct: 124 QEISGYIDY 132
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEISSLVNY 9
           Q+IS +V Y
Sbjct: 912 QQISEIVGY 920
>XP_005254242
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QEISSLVN 8
           QE+ SLVN
Sbjct: 212 QELLSLVN 219
>XP_006720186
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 311 KKISSKINY 319
>XP_005267620
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 328 KKISSKINY 336
>XP_006720185
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 368 KKISSKINY 376
>XP_005267618
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QEISSLVNY 9
           ++ISS +NY
Sbjct: 531 KKISSKINY 539
>XP_006717380
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EISSLVNY 9
           EIS LV+Y
Sbjct: 467 EISPLVSY 474
>XP_005251811
          Length = 3060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251810
          Length = 3062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251809
          Length = 3063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251808
          Length = 3075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251807
          Length = 3088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251805
          Length = 3090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251803
          Length = 3091

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717050
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251802
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717049
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717048
          Length = 3101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717047
          Length = 3101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717046
          Length = 3103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717045
          Length = 3104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    QEISSLV 7
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006714232
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  QEISSLVNY 9
          QEIS  ++Y
Sbjct: 14 QEISGYIDY 22
>XP_005262940
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QEISSLVNY 9
           QEIS  ++Y
Sbjct: 124 QEISGYIDY 132
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.122    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,698
Number of extensions: 980
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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