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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001073890                                                           18    1935
XP_006722755                                                           18    1935
NP_055146                                                              17    2528
NP_000880                                                              17    2528
XP_006719439                                                           17    2528
XP_005268909                                                           17    2528
XP_005268908                                                           17    2528
XP_005262932                                                           17    2528
NP_055646                                                              17    3301
NP_004723                                                              17    3301
XP_005256906                                                           17    3301
XP_006713495                                                           17    3301
NP_055782                                                              17    4312
XP_006725604                                                           17    4312
XP_006725603                                                           17    4312
XP_006725602                                                           17    4312
XP_006725601                                                           17    4312
XP_006725600                                                           17    4312
XP_005254293                                                           17    4312
XP_005254289                                                           17    4312
XP_005254292                                                           17    4312
XP_005254291                                                           17    4312
XP_005254290                                                           17    4312
NP_006124                                                              16    5631
NP_079058                                                              16    5631
XP_005274287                                                           16    5631
NP_001277046                                                           16    7355
NP_001277047                                                           16    7355
NP_001074011                                                           16    7355
NP_060170                                                              15    9605
NP_001229658                                                           15    9605
NP_071434                                                              15    9605
XP_006723595                                                           15    9605

>NP_001073890
          Length = 1703

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCSVAELAI 9
            QC+V ELA+
Sbjct: 1458 QCAVVELAL 1466



>XP_006722755
          Length = 1722

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QCSVAELAI 9
            QC+V ELA+
Sbjct: 1458 QCAVVELAL 1466



>NP_055146
          Length = 501

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCSVAELAI 9
           QC + ELAI
Sbjct: 157 QCEIPELAI 165



>NP_000880
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QCSVAELA 8
           +CSVAEL+
Sbjct: 512 ECSVAELS 519



>XP_006719439
          Length = 782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QCSVAELA 8
           +CSVAEL+
Sbjct: 512 ECSVAELS 519



>XP_005268909
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QCSVAELA 8
           +CSVAEL+
Sbjct: 512 ECSVAELS 519



>XP_005268908
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QCSVAELA 8
           +CSVAEL+
Sbjct: 512 ECSVAELS 519



>XP_005262932
          Length = 342

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QCSVAELAI 9
           QC + ELAI
Sbjct: 157 QCEIPELAI 165



>NP_055646
          Length = 2925

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    CSVAELAI 9
            CSV++LAI
Sbjct: 1514 CSVSDLAI 1521



>NP_004723
          Length = 404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   CSVAELAI 9
           C+VA+LAI
Sbjct: 342 CTVAQLAI 349



>XP_005256906
          Length = 375

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   CSVAELAI 9
           C+VA+LAI
Sbjct: 313 CTVAQLAI 320



>XP_006713495
          Length = 2969

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    CSVAELAI 9
            CSV++LAI
Sbjct: 1558 CSVSDLAI 1565



>NP_055782
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_006725604
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_006725603
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_006725602
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_006725601
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_006725600
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_005254293
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_005254289
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_005254292
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_005254291
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>XP_005254290
          Length = 1017

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSVAELAI 9
           CSV ELA+
Sbjct: 812 CSVEELAL 819



>NP_006124
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  CSVAELAI 9
          C +AE+AI
Sbjct: 69 CMIAEMAI 76



>NP_079058
          Length = 299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QCSVAELA 8
           QC V ELA
Sbjct: 147 QCQVRELA 154



>XP_005274287
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  CSVAELAI 9
          C +AE+AI
Sbjct: 69 CMIAEMAI 76



>NP_001277046
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QCSVAELAI 9
           +C+V+E+A+
Sbjct: 169 KCTVSEMAL 177



>NP_001277047
          Length = 140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QCSVAELAI 9
           +C+V+E+A+
Sbjct: 121 KCTVSEMAL 129



>NP_001074011
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QCSVAEL 7
           QCS AEL
Sbjct: 572 QCSPAEL 578



>NP_060170
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  QCSVAE 6
          +CSVAE
Sbjct: 73 ECSVAE 78



>NP_001229658
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  QCSVAE 6
          +CSVAE
Sbjct: 73 ECSVAE 78



>NP_071434
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  CSVAEL 7
          CSVAE+
Sbjct: 30 CSVAEI 35



>XP_006723595
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSVAELAI 9
           CSVAE  I
Sbjct: 208 CSVAETEI 215



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.126    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 482,294
Number of extensions: 550
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)