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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056046                                                              17    2528
XP_006718233                                                           17    2528
NP_001269308                                                           17    4312
NP_004477                                                              17    4312
NP_079334                                                              17    4312
NP_001243529                                                           17    4312
NP_001269307                                                           17    4312
NP_001243528                                                           17    4312
NP_001243530                                                           17    4312
XP_005274513                                                           17    4312
XP_005251989                                                           17    4312
XP_005251988                                                           17    4312
XP_005251987                                                           17    4312
NP_060606                                                              16    5631
NP_001193775                                                           16    5631
NP_116207                                                              16    5631
NP_056127                                                              16    5631
NP_057340                                                              16    5631
XP_005272458                                                           16    5631
XP_006716327                                                           16    5631
XP_006714407                                                           16    5631
XP_006714405                                                           16    5631
XP_005263349                                                           16    5631
XP_005263348                                                           16    5631
XP_005263347                                                           16    5631
XP_005263346                                                           16    5631
XP_005263345                                                           16    5631
XP_005263344                                                           16    5631
XP_005263343                                                           16    5631
XP_005263342                                                           16    5631
XP_005263341                                                           16    5631
XP_005263340                                                           16    5631
XP_005263339                                                           16    5631
NP_699163                                                              16    5631
NP_060318                                                              15    9605
NP_004924                                                              15    9605
NP_036415                                                              15    9605

>NP_056046
          Length = 1436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QCSLSRVR 8
            +CSL+R+R
Sbjct: 1186 ECSLARIR 1193



>XP_006718233
          Length = 782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QCSLSRVR 8
           +CSL+R+R
Sbjct: 532 ECSLARIR 539



>NP_001269308
          Length = 551

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 246 CQLCRVRR 253



>NP_004477
          Length = 1002

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QCSLSRVR 8
           +CS+SRV+
Sbjct: 426 ECSMSRVQ 433



>NP_079334
          Length = 759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 246 CQLCRVRR 253



>NP_001243529
          Length = 717

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 233 CQLCRVRR 240



>NP_001269307
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 120 CQLCRVRR 127



>NP_001243528
          Length = 736

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 223 CQLCRVRR 230



>NP_001243530
          Length = 746

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CSLSRVRR 9
           C L RVRR
Sbjct: 233 CQLCRVRR 240



>XP_005274513
          Length = 226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CSLSRVRR 9
           CSLSR +R
Sbjct: 130 CSLSRQKR 137



>XP_005251989
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QCSLSRVR 8
           +CS+SRV+
Sbjct: 399 ECSMSRVQ 406



>XP_005251988
          Length = 1002

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QCSLSRVR 8
           +CS+SRV+
Sbjct: 426 ECSMSRVQ 433



>XP_005251987
          Length = 1029

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QCSLSRVR 8
           +CS+SRV+
Sbjct: 453 ECSMSRVQ 460



>NP_060606
          Length = 3477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QCSLSRVRR 9
           +C L+R+RR
Sbjct: 759 RCRLNRLRR 767



>NP_001193775
          Length = 1892

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QCSLSRVRR 9
           +C L+R+RR
Sbjct: 759 RCRLNRLRR 767



>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QCSLSRV 7
           QC LSRV
Sbjct: 282 QCHLSRV 288



>NP_056127
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4211 SLSRIRR 4217



>NP_057340
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   CSLSRVRR 9
           CS+SRV++
Sbjct: 421 CSVSRVKQ 428



>XP_005272458
          Length = 271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCSLSRVR 8
           QC LSR++
Sbjct: 164 QCQLSRLK 171



>XP_006716327
          Length = 349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCSLSRVR 8
           QC LSR++
Sbjct: 242 QCQLSRLK 249



>XP_006714407
          Length = 5004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4210 SLSRIRR 4216



>XP_006714405
          Length = 4103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 3309 SLSRIRR 3315



>XP_005263349
          Length = 4410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 3616 SLSRIRR 3622



>XP_005263348
          Length = 4443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 3649 SLSRIRR 3655



>XP_005263347
          Length = 4640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4232 SLSRIRR 4238



>XP_005263346
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4189 SLSRIRR 4195



>XP_005263345
          Length = 4991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4197 SLSRIRR 4203



>XP_005263344
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4211 SLSRIRR 4217



>XP_005263343
          Length = 5009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4215 SLSRIRR 4221



>XP_005263342
          Length = 5025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4231 SLSRIRR 4237



>XP_005263341
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4232 SLSRIRR 4238



>XP_005263340
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4232 SLSRIRR 4238



>XP_005263339
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SLSRVRR 9
            SLSR+RR
Sbjct: 4232 SLSRIRR 4238



>NP_699163
          Length = 349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QCSLSRVR 8
           QC LSR++
Sbjct: 242 QCQLSRLK 249



>NP_060318
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    QCSLSR 6
            QC+LSR
Sbjct: 1055 QCALSR 1060



>NP_004924
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLSRVRR 9
          +LSRVRR
Sbjct: 39 ALSRVRR 45



>NP_036415
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QCSLSRVRR 9
           +C L R+RR
Sbjct: 117 RCCLRRLRR 125



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.131    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 556,929
Number of extensions: 787
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)