Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000205                                                              18    1482
NP_001273028                                                           17    2528
NP_005275                                                              17    2528
NP_955381                                                              17    3301
XP_006713444                                                           17    3301
NP_001124149                                                           17    4312
NP_002218                                                              17    4312
NP_061842                                                              17    4312
NP_114088                                                              17    4312
NP_061721                                                              17    4312
XP_005270898                                                           17    4312
XP_006710687                                                           17    4312
NP_001005186                                                           17    4312
NP_114072                                                              16    5631
NP_599025                                                              16    5631
NP_001035544                                                           16    5631
NP_001268662                                                           16    5631
NP_075062                                                              16    5631
NP_003459                                                              16    5631
NP_001185741                                                           16    5631
NP_001268661                                                           16    5631
XP_006718052                                                           16    5631
XP_006718051                                                           16    5631
NP_003683                                                              16    5631
NP_112174                                                              16    5631
NP_602298                                                              16    5631
NP_061178                                                              16    5631
NP_000264                                                              16    7355
NP_001140168                                                           16    7355
NP_001140167                                                           16    7355
NP_055876                                                              16    7355
NP_001140166                                                           16    7355
XP_003960323                                                           16    7355
XP_005274599                                                           16    7355
XP_005274598                                                           16    7355
XP_006716804                                                           16    7355
XP_003959962                                                           16    7355
NP_079162                                                              16    7355
NP_005621                                                              15    9605
NP_055830                                                              15    9605
NP_039249                                                              15    9605
NP_008983                                                              15    9605
NP_663314                                                              15    9605
NP_055271                                                              15    9605
NP_001186421                                                           15    9605
NP_078858                                                              15    9605
NP_001278232                                                           15    9605
NP_001278214                                                           15    9605
NP_036419                                                              15    9605
NP_001171655                                                           15    9605
NP_000346                                                              15    9605
NP_004708                                                              15    9605
NP_055052                                                              15    9605
XP_005276508                                                           15    9605
XP_005276920                                                           15    9605
XP_005259579                                                           15    9605
XP_005259578                                                           15    9605
XP_005268314                                                           15    9605
XP_006717830                                                           15    9605
XP_005269759                                                           15    9605
XP_005252506                                                           15    9605
XP_006716237                                                           15    9605
XP_006716236                                                           15    9605
XP_006716235                                                           15    9605
XP_006713621                                                           15    9605
XP_006713620                                                           15    9605
XP_005264465                                                           15    9605
XP_005264464                                                           15    9605
XP_005264309                                                           15    9605
XP_005264308                                                           15    9605
XP_006712048                                                           15    9605
XP_006710702                                                           15    9605
XP_006710154                                                           15    9605
XP_005275803                                                           15    9605
NP_001030014                                                           15    9605
NP_787118                                                              15    9605
NP_001019851                                                           15    9605
>NP_000205
          Length = 1218

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           QCL  R AC
Sbjct: 884 QCLNGRIAC 892
>NP_001273028
          Length = 377

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL  RAAC
Sbjct: 224 CLAERAAC 231
>NP_005275
          Length = 362

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL  RAAC
Sbjct: 209 CLAERAAC 216
>NP_955381
          Length = 814

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CLR+R  C
Sbjct: 217 CLRSRVRC 224
>XP_006713444
          Length = 216

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CLRARAAC 9
          C R+R AC
Sbjct: 5  CARSRGAC 12
>NP_001124149
          Length = 379

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  CLRARAAC 9
          CLRA A C
Sbjct: 39 CLRALAFC 46
>NP_002218
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CLRARAAC 9
          C+RA  AC
Sbjct: 61 CIRAAQAC 68
>NP_061842
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           +CLR  A C
Sbjct: 349 KCLRTHAPC 357
>NP_114088
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QCLRARAAC 9
          Q  RA+AAC
Sbjct: 85 QLCRAKAAC 93
>NP_061721
          Length = 963

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QCLRARAAC 9
          Q  RA+AAC
Sbjct: 85 QLCRAKAAC 93
>XP_005270898
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CLRARAAC 9
          C+RA  AC
Sbjct: 61 CIRAAQAC 68
>XP_006710687
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  CLRARAAC 9
          C+RA  AC
Sbjct: 61 CIRAAQAC 68
>NP_001005186
          Length = 317

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  AAC
Sbjct: 145 CIRLAAAC 152
>NP_114072
          Length = 694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C RA+A C
Sbjct: 111 CERAKAGC 118
>NP_599025
          Length = 758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 61 QCSRARA 67
>NP_001035544
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 40 QCSRARA 46
>NP_001268662
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 61 QCSRARA 67
>NP_075062
          Length = 759

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 61 QCSRARA 67
>NP_003459
          Length = 585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C RA+A C
Sbjct: 109 CERAKAGC 116
>NP_001185741
          Length = 454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           +C   RAAC
Sbjct: 195 ECFLRRAAC 203
>NP_001268661
          Length = 723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 61 QCSRARA 67
>XP_006718052
          Length = 330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           CLR  A C
Sbjct: 107 CLRCEAPC 114
>XP_006718051
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           CLR  A C
Sbjct: 107 CLRCEAPC 114
>NP_003683
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           +C   RAAC
Sbjct: 121 ECFLRRAAC 129
>NP_112174
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           CLR  A C
Sbjct: 107 CLRCEAPC 114
>NP_602298
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  QCLRARA 7
          QC RARA
Sbjct: 61 QCSRARA 67
>NP_061178
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QCLRARA 7
           QCL ARA
Sbjct: 640 QCLAARA 646
>NP_000264
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LRARAAC 9
          LRA AAC
Sbjct: 71 LRAAAAC 77
>NP_001140168
          Length = 835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  A+C
Sbjct: 744 CVRVHASC 751
>NP_001140167
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  A+C
Sbjct: 722 CVRVHASC 729
>NP_055876
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  A+C
Sbjct: 722 CVRVHASC 729
>NP_001140166
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  A+C
Sbjct: 722 CVRVHASC 729
>XP_003960323
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 215 CYRPRARC 222
>XP_005274599
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LRARAAC 9
          LRA AAC
Sbjct: 71 LRAAAAC 77
>XP_005274598
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LRARAAC 9
          LRA AAC
Sbjct: 71 LRAAAAC 77
>XP_006716804
          Length = 1089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           C+R  A+C
Sbjct: 722 CVRVHASC 729
>XP_003959962
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 215 CYRPRARC 222
>NP_079162
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R R AC
Sbjct: 213 CCRRRRAC 220
>NP_005621
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           CL  R AC
Sbjct: 587 CLGRRGAC 594
>NP_055830
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL+  A+C
Sbjct: 764 CLQVHASC 771
>NP_039249
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C RA A C
Sbjct: 52 CARASALC 59
>NP_008983
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C RA A C
Sbjct: 52 CARASALC 59
>NP_663314
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CLRARAA 8
           C++ARAA
Sbjct: 277 CVQARAA 283
>NP_055271
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CLRARAA 8
           C++ARAA
Sbjct: 288 CVQARAA 294
>NP_001186421
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CLRARAA 8
           C++ARAA
Sbjct: 274 CVQARAA 280
>NP_078858
          Length = 4981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1    QCLRARAAC 9
            QC R   AC
Sbjct: 4158 QCPRLEGAC 4166
>NP_001278232
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1    QCLRARAAC 9
            QC R   AC
Sbjct: 4160 QCPRLEGAC 4168
>NP_001278214
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1    QCLRARAAC 9
            QC R   AC
Sbjct: 4160 QCPRLEGAC 4168
>NP_036419
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           QC+   A+C
Sbjct: 406 QCIPGNASC 414
>NP_001171655
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLRARAA 8
           CL+AR A
Sbjct: 240 CLKARVA 246
>NP_000346
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CLRARAA 8
           CL+AR A
Sbjct: 267 CLKARVA 273
>NP_004708
          Length = 1065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2    CLRARAAC 9
            C R RA C
Sbjct: 1004 CQRNRAVC 1011
>NP_055052
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   QCLRARAAC 9
           QC   RA C
Sbjct: 334 QCFCLRATC 342
>XP_005276508
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C RA A C
Sbjct: 47 CARAGAGC 54
>XP_005276920
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 255 CARYRALC 262
>XP_005259579
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL+  A+C
Sbjct: 433 CLQVHASC 440
>XP_005259578
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL+  A+C
Sbjct: 798 CLQVHASC 805
>XP_005268314
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C RA A C
Sbjct: 47 CARAGAGC 54
>XP_006717830
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CLRARAA 8
           C++ARAA
Sbjct: 102 CVQARAA 108
>XP_005269759
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CLRARAA 8
           C++ARAA
Sbjct: 102 CVQARAA 108
>XP_005252506
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 255 CARYRALC 262
>XP_006716237
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 435 CQRNRAVC 442
>XP_006716236
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 961 CQRNRAVC 968
>XP_006716235
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2    CLRARAAC 9
            C R RA C
Sbjct: 996  CQRNRAVC 1003
>XP_006713621
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           QC+   A+C
Sbjct: 413 QCIPGNASC 421
>XP_006713620
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QCLRARAAC 9
           QC+   A+C
Sbjct: 413 QCIPGNASC 421
>XP_005264465
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C+  RA C
Sbjct: 80 CMTVRAVC 87
>XP_005264464
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C+  RA C
Sbjct: 80 CMTVRAVC 87
>XP_005264309
          Length = 1324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL A A+C
Sbjct: 990 CLSAPASC 997
>XP_005264308
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL A A+C
Sbjct: 884 CLSAPASC 891
>XP_006712048
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CLRARAAC 9
           CL A A+C
Sbjct: 915 CLSAPASC 922
>XP_006710702
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  QCLRAR 6
          +CLRAR
Sbjct: 61 RCLRAR 66
>XP_006710154
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LRARAAC 9
          LRA AAC
Sbjct: 32 LRAPAAC 38
>XP_005275803
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C RA A C
Sbjct: 47 CARAGAGC 54
>NP_001030014
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   CLRARAAC 9
           C R RA C
Sbjct: 255 CARYRALC 262
>NP_787118
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   CLRARAA 8
           CL ARAA
Sbjct: 178 CLPARAA 184
>NP_001019851
          Length = 155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 5/8 (62%)

Query: 2  CLRARAAC 9
          C+  RA C
Sbjct: 80 CMTVRAVC 87
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.131    0.497 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 534,981
Number of extensions: 1167
Number of successful extensions: 77
Number of sequences better than 10000.0: 77
Number of HSP's gapped: 77
Number of HSP's successfully gapped: 77
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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