Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_001275707                                                           16    7355
NP_004415                                                              16    7355
XP_006720921                                                           16    7355
XP_006720920                                                           16    7355
XP_005255213                                                           16    7355
XP_005255212                                                           16    7355
XP_005268846                                                           16    7355
XP_005268845                                                           16    7355
>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QAVSESTV 8
            QAVSESTV
Sbjct: 1373 QAVSESTV 1380
>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QAVSESTV 8
            QAVSESTV
Sbjct: 1373 QAVSESTV 1380
>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QAVSESTV 8
            QAVSESTV
Sbjct: 1373 QAVSESTV 1380
>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QAVSESTV 8
            QAVSESTV
Sbjct: 1373 QAVSESTV 1380
>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    QAVSESTV 8
            QAVSESTV
Sbjct: 1373 QAVSESTV 1380
>NP_001275707
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 553 AISEGTVL 560
>NP_004415
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 730 AISEGTVL 737
>XP_006720921
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 729 AISEGTVL 736
>XP_006720920
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 731 AISEGTVL 738
>XP_005255213
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 782 AISEGTVL 789
>XP_005255212
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVSESTVL 9
           A+SE TVL
Sbjct: 783 AISEGTVL 790
>XP_005268846
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QAVSESTV 8
          QAVS STV
Sbjct: 3  QAVSPSTV 10
>XP_005268845
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  QAVSESTV 8
          QAVS STV
Sbjct: 3  QAVSPSTV 10
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.105    0.221 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 210,776
Number of extensions: 250
Number of successful extensions: 13
Number of sequences better than 10000.0: 13
Number of HSP's gapped: 13
Number of HSP's successfully gapped: 13
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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